Gastric acid reducing agents
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Excessive neutrophil presence and activation is important in a number of acute and chronic inflammatory diseases. The CXCR2 chemokine receptor is important in controlling the extravasation and activation of neutrophils.
12p vienzym2711 03-04-2020 12 1 Download
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The urea cycle enzyme arginase (EC 3.5.3.1) hydrolyzes L-arginine to L-ornithine and urea. Mammalian arginases require manganese, have a highly alkaline pH optimum and are resistant to reducing agents. The gastric human pathogen,Helicobacter pylori, also has a complete urea cycle and contains therocFgene encoding arginase (RocF), which is involved in the pathogenesis ofH. pyloriinfection. Its arginase is specifically involved in acid resistance and inhibits host nitric oxide production.
11p dell39 03-04-2013 46 3 Download