Gram-negative bacteria

The antimicrobial activity of the products was evaluated and the results revealed that compounds 8f and 15f showed strong activity against gram-positive bacteria while compound 15d showed the highest activity against gramnegative bacteria. Moreover, compounds 15b, 8d, 8e, 8c, 8l, and 8j exhibited significant antifungal activity. In addition, the antitumoral activity of the synthesized products against different cancer cell lines was determined and the results revealed that compound 12c was the most active against MCF-7, HepG-2, HCT-116, and HeLa with IC50 values of 0.51, 0.72, 0.95, and 0.

22p langthannam 29-12-2021 14 0   Download

TetR-family transcriptional regulators (TFTRs) are DNA binding factors that regulate gene expression in bacteria. Well-studied TFTRs, such as AcrR, which regulates efflux pump expression, are usually encoded alongside target operons. Recently, it has emerged that there are many TFTRs which act as global multi-target regulators.

12p visilicon2711 20-08-2021 7 1   Download

The polynucleotide phosphorylase (PNPase) is conserved among both Gram-positive and Gramnegative bacteria. As a core part of the Escherichia coli degradosome, PNPase is involved in maintaining proper RNA levels within the bacterial cell.

15p vilichoo2711 25-06-2021 9 1   Download

The aim of the present work to purify and characterize β-lactamase from two clinical isolates: Gram-positive S. sciuri and Gramnegative K. pneumoniae.

15p trinhthamhodang1215 23-09-2020 9 1   Download

Optimal therapy for colorectal carcinoma (CRC), a frequently diagnosed malignancy, does not exist. Some of colicins and microcins, ribosomally synthesized peptides by gramnegative bacteria, have shown significant biological activity specifically against different cancer cells in vitro and in vivo conditions.

7p vikuala271 13-06-2020 12 0   Download

PAL is a peptidoglycan-associated lipoprotein found in the cell membranes of many Gramnegative bacteria. The presence of PAL has been demonstrated in Escherichia coli and many bacteria. In this paper, we show the presence of a gene coding for a PAL-like protein in C. vinosum, a photosynthetic bacteria and the partial sequence of the PAL gene.

7p vitamix 19-02-2019 24 0   Download

HACEK organisms are a group of fastidious, slow-growing, gram-negative bacteria whose growth requires an atmosphere of carbon dioxide. Species belonging to this group include several Haemophilus species, Actinobacillus actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens, and Kingella kingae. HACEK bacteria normally reside in the oral cavity and have been associated with local infections in the mouth. They are also known to cause severe systemic infections— most often bacterial endocarditis, which can develop on either native or prosthetic valves (Chap. 118).

7p ozon_ozon 26-04-2012 46 2   Download

Pathogenesis of Fever Pyrogens The term pyrogen is used to describe any substance that causes fever. Exogenous pyrogens are derived from outside the patient; most are microbial products, microbial toxins, or whole microorganisms. The classic example of an exogenous pyrogen is the lipopolysaccharide (endotoxin) produced by all gramnegative bacteria. Pyrogenic products of gram-positive organisms include the enterotoxins of Staphylococcus aureus and the group A and B streptococcal toxins, also called superantigens.

5p ongxaemnumber1 29-11-2010 68 2   Download