![](images/graphics/blank.gif)
Haplotype analysis
-
Part 2 book "PCR Protocols" includes content: Linking emulsion PCR haplotype analysis, the many faces of MLPA, assessing gene specific methylation using HRM-Based analysis, asynchronous PCR, enhanced solid phase PCR for increased loading of amplicon onto solid support, application of blocking oligonucleotides to improve signal to noise ratio in a PCR,...and other contents.
179p
oursky06
17-10-2023
3
1
Download
-
Seed dormancy is an adaptive trait employed by flowering plants to avoid harsh environmental conditions for the continuity of their next generations. In cereal crops, moderate seed dormancy could help prevent pre-harvest sprouting and improve grain yield and quality.
13p
vinarcissa
21-03-2023
5
1
Download
-
Previously, it was shown that the HFE gene (associated with human hereditary hemochromatosis) has several haplotypes of intronic polymorphisms. Some haplotype frequencies are race specific and hence can be used in phylogenetic analysis.
13p
vinarcissa
21-03-2023
2
1
Download
-
The most economically important Citrus species originated by natural interspecific hybridization between four ancestral taxa (Citrus reticulata, Citrus maxima, Citrus medica, and Citrus micrantha) and from limited subsequent interspecific recombination as a result of apomixis and vegetative propagation.
19p
vinarcissa
21-03-2023
5
1
Download
-
It has been shown that hematological traits are strongly associated with the metabolism and the immune system in domestic pig. However, little is known about the genetic architecture of hematological traits.
9p
vinarcissa
21-03-2023
5
1
Download
-
Traditional single nucleotide polymorphism (SNP) genome-wide association analysis (GWAA) can be inefficient because single SNPs provide limited genetic information about genomic regions. On the other hand, using haplotypes in the statistical analysis may increase the extent of linkage disequilibrium (LD) between haplotypes and causal variants and may also potentially capture epistastic interactions between variants within a haplotyped locus, providing an increase in the power and robustness of the association studies.
12p
vihagrid
30-01-2023
11
4
Download
-
Ticks are a problem for cattle production mainly in tropical and subtropical regions, because they generate great economic losses. Acaricides and vaccines have been used to try to keep tick populations under control. This has been proven difficult given the resistance to acaricides and vaccines observed in ticks.
12p
vihagrid
30-01-2023
7
3
Download
-
G-protein subunit beta 1 like (GNB1L) encodes a G-protein beta-subunit-like polypeptide. Chicken GNB1L is upregulated in the breast muscle of high feed efficiency chickens, and its expression is 1.52-fold that in low feed efficiency chickens. However, no report has described the effects of GNB1L indels on the chicken carcass and growth traits.
7p
vihagrid
30-01-2023
6
3
Download
-
Associations between haplotypes and quantitative traits provide valuable information about the genetic basis of complex human diseases. Haplotypes also provide an effective way to deal with untyped SNPs. Two major challenges arise in haplotype-based association analysis of family data.
11p
vihagrid
30-01-2023
7
3
Download
-
In the past decade, the brown marmorated stink bug (BMSB), Halyomorpha halys (Hemiptera: Pentatomidae) has caused extensive damage to global agriculture. As a high-risk pest for many countries, including New Zealand, it is important to explore its genetic diversity to enhance our knowledge and devise management strategies for BMSB populations.
16p
vihagrid
30-01-2023
7
3
Download
-
Glutinous rice as a special endosperm type is consumed as a staple food in East Asian countries by consumers’ preference. Genetic studies on glutinous rice could be conducive to improve rice quality and understand its development and evolution.
15p
vihagrid
30-01-2023
13
3
Download
-
The genetic origins of Uralic speakers from across a vast territory in the temperate zone of North Eurasia have remained elusive. Previous studies have shown contrasting proportions of Eastern and Western Eurasian ancestry in their mitochondrial and Y chromosomal gene pools.
20p
vigalileogalilei
27-02-2022
13
1
Download
-
Third-generation sequencing technologies have advanced the progress of the biological research by generating reads that are substantially longer than second-generation sequencing technologies. However, their notorious high error rate impedes straightforward data analysis and limits their application. A handful of error correction methods for these error-prone long reads have been developed to date.
17p
vigalileogalilei
27-02-2022
9
1
Download
-
The mapping resolution of genome-wide association studies (GWAS) is limited by historic recombination events and effects are often assigned to haplotype blocks rather than individual SNPs. It is not clear how many of the SNPs in the block, and which ones, are causative.
6p
vialfrednobel
29-01-2022
10
1
Download
-
Allele expression (AE) analysis robustly measures cis-regulatory effects. Here, we present and demonstrate the utility of a vast AE resource generated from the GTEx v8 release, containing 15,253 samples spanning 54 human tissues for a total of 431 million measurements of AE at the SNP level and 153 million measurements at the haplotype level.
12p
viarchimedes
26-01-2022
7
1
Download
-
Resolving genomes at haplotype level is crucial for understanding the evolutionary history of polyploid species and for designing advanced breeding strategies. Polyploid phasing still presents considerable challenges, especially in regions of collapsing haplotypes.
22p
viarchimedes
26-01-2022
9
0
Download
-
Systemic lupus erythematosus (SLE) is a clinically heterogeneous autoimmune disease characterized by the development of anti-nuclear antibodies. Susceptibility to SLE is multifactorial, with a combination of genetic and environmental risk factors contributing to disease development.
26p
viarchimedes
26-01-2022
9
0
Download
-
Admixture occurs when previously isolated populations come together and exchange genetic material. We hypothesize that admixture can enable rapid adaptive evolution in human populations by introducing novel genetic variants (haplotypes) at intermediate frequencies, and we test this hypothesis through the analysis of whole genome sequences sampled from admixed Latin American populations in Colombia, Mexico, Peru, and Puerto Rico.
12p
viarchimedes
26-01-2022
10
0
Download
-
Ablepharus Lichtenstein, 1823, which includes ten species, is distributed in eastern Europe and Asia. Four species are recorded in Turkey: A. kitaibelii, A. chernovi, A. bivittatus, and A. budaki. After molecular and morphological studies in Anatolia, the phylogenetic relationship of the genus is still very complicated. Here, we investigate the taxonomic status of Ablepharus in Anatolia using morphological and molecular methods. The genetic structure of Ablepharus populations in Anatolia was analyzed using both the nuclear (CMOS) and mitochondrial (cyt b and COI) gene regions.
12p
dolomite36
30-12-2021
15
0
Download
-
Populations of common quail (Coturnix coturnix) have recently been declining in Europe. This is the first study of common quail in eastern Europe using molecular markers. The mtDNA D-loop genetic diversity of common quails migrating through Ukraine was analyzed and compared with that of birds migrating via northern Spain in 2017–2018. In samples from 77 birds, 32 polymorphic sites and 30 haplotypes (H1–H30) were identified, only 4 of which were common for birds sampled in both Ukraine and Spain. Phylogenetic analysis indicated 2 well-supported clades.
4p
dolomite36
30-12-2021
10
0
Download
CHỦ ĐỀ BẠN MUỐN TÌM
![](images/graphics/blank.gif)