HBV infection

Underlying liver disease is correlated with hepatocellular carcinoma (HCC) development in patients with hepatitis B virus (HBV) infection. However, the impact of hepatic inflammation and fibrosis on the patients’ prognoses remains unclear.

9p vishanshan 27-06-2024 1 1   Download

HBV infection is the leading risk factor for HCC. HBV infection has been confirmed to be associated with the exhaustion status of CD8+ T cells and immunotherapeutic efficacy in HCC. In this study, we aimed to investigate the prognostic value of the CD8+ T-cell exhaustion signature and immunotherapy response in patients with HBV-related HCC.

15p vishanshan 27-06-2024 1 1   Download

Hepatitis B virus (HBV) infections is an important public health problem worldwide and closely affect extrahepatic cancer. Several recent studies have investigated the relationship between HBV infection and head and neck cancer (HNC), but their findings were inconsistent.In order to address the limitations of small sample sizes, we conducted a meta-analysis to assess the association between HBV and HNC.

10p vikoch 27-06-2024 2 1   Download

Ebook "Genetic diversity and variability of hepatitis B virus (HBV)" provides readers with contents including: Chapter 1 - Introduction; Chapter 2 - HBV epidemiology in Latin America and the Caribbean (LAC) region; Chapter 3 - HBV variants and mutants and its Impact on the LAC region; Chapter 4 - Conclusions;...

124p dongmelo 27-05-2024 4 3   Download

Worldwide, over 350 million people are chronically infected with the hepatitis B virus (HBV) and are at increased risk of developing progressive liver diseases. The confinement of HBV replication to the liver, which also acts as the central hub for metabolic and nutritional regulation, emphasizes the interlinked nature of host metabolism and the disease.

13p vioraclene 31-03-2024 6 2   Download

PD-1 is an immunoinhibitory receptor which plays vital role in pathogenesis of hepatitis B virus (HBV) infection. The aim of this study was to understand the relationship between PD-1.1 polymorphism in HBV infection and liver disease progression.

6p vilarry 12-03-2024 4 2   Download

Ebook "Hepatitis B virus: Methods and protocols" details protocols and techniques ranging from cell culture studies to in vivo and clinical immunology. The chapters in this book discuss treatments of in vitro infection systems, analysis and quantification of cccDNA and its mutations; in vitro polymerase activity assays; cellular trafficking of core proteins; intracellular calcium metabolism; detection, cloning, and sequencing of HBV markers; and new strategies aimed at exploiting new mechanisms for drug discovery.

301p lucchinguyen 28-12-2023 5 2   Download

Opportunistic viral infections such as Cytomegalovirus (CMV), Hepatitis B (HBV) and C (HCV) are often prevalent in HIV patients undergoing antiretroviral therapy (ART) thereby shortening the life span of infected patients. The co-infection of CMV, HBV and HCV among HIV positive patients attending ART clinics across hospitals in Ekiti State, Nigeria, were studied.

11p vikissinger 21-12-2023 4 1   Download

The immunosuppressive PD-1/PD-L1 (programmed cell death-1/ programmed cell death ligand-1) signaling pathway is considered to play an important role in the pathogenesis of HBV infection.

7p vispacex 13-11-2023 8 2   Download

This case-control study aimed to determine the association between PD-1.9 polymorphism and the risk of HCC in the cohort of chronic HBV-infected patients. Subject and method: Genotyping of PD-1.9 polymorphism was performed by direct sanger sequencing in 499 HBV-infected patients.

7p vishekhar 01-11-2023 0 0   Download

Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death, worldwide. The predominant causative factor for HCC is hepatitis B virus (HBV) infection. We conducted a meta-analysis to estimate the efficacy and safety of PD-1/PD-L1 inhibitors combined with anti-angiogenic therapy for the first-line treatment of the unresectable HCC and to evaluate the benefits of different geographic regions and etiology stratifications.

11p visharma 20-10-2023 8 3   Download

The results obtained in this work demonstrate a high prevalence of CHB/OBI in the region and indicate the need for further large-scale studies of HBV in order to improve strategies for disease control and prevention in the Vietnam.

8p vineville 08-02-2023 4 1   Download

Persons who experience homelessness remain at increased risk for three viral blood-borne infections: human immunodefciency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV). We assessed the yield of testing and linkage to care programs targeting this population for these infections in the United States (US).

16p viferrari 28-11-2022 6 2   Download

Burden disease related to chronic HBV infection is increasing worldwide. In this line of thought, this study aims to analyze national and regional epidemiology of Hepatitis B and it’s temporal trends based on Brazilian reported cases.

10p viferrari 29-10-2022 8 2   Download

Interferon-stimulated gene 20 (ISG20) plays an important role in viral infection and cancers. This study investigated the association between ISG20 rs4566136 polymorphism with HBV-related hepatocellular carcinoma.

10p viangelamerkel 18-07-2022 4 2   Download

Previous studies have observed a close association between hepatitis B virus (HBV) infection and hepatocellular carcinoma (HCC) as well as extrahepatic cancers. However, research concerning the effect of HBV infection on the risk of colorectal cancer (CRC) is rare and inconsistent. This study aims to determine the relationship between HBV infection and new-onset CRC.

10p vimahuateng 26-11-2021 11 2   Download

Transarterial chemoembolization (TACE) is an effective treatment for patients with hepatocellular carcinoma (HCC). However, the impact of hepatitis B viral (HBV) infection and body mass index (BMI) on TACE is controversial. The present study aimed to compare the influence of HBV and high BMI on TACE outcomes in advanced HCC.

17p vimahuateng 26-11-2021 4 1   Download

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths in Africa. In Africa, the major causes of HCC include chronic infection with hepatitis B virus (HBV) and/or hepatitis C virus (HCV). Knowledge of the changes in the incidence of viral hepatitis-associated HCC over time and the factors responsible for such changes is key in informing policies for the prevention of viral hepatitis-associated HCC in Africa.

13p vimahuateng 26-11-2021 8 0   Download

Hepatitis B Virus (HBV) contributes to liver carcinogenesis via various epigenetic mechanisms. The newly defined epigenetics, epitranscriptomics regulation, has been reported to involve in multiple cancers including Hepatocellular Carcinoma (HCC). Our previous study found that HBx, HBV encodes X protein, mediated H3K4me3 modification in WDR5-dependent manner to involve in HBV infection and contribute to oncogene expression.

11p vimahuateng 26-11-2021 6 1   Download

Thalassemia is one of commonest hereditary disease worldwide, prevalent in humid climates and affects all races. The Transfusion Dependent Thalassemias require regular blood transfusion to survive. The thalassemia patients require lifelong blood transfusion on regular basis- usually administered every 2 to 5 weeks. Due to regular blood transfusion, transfusion transmitted disease e.g. Hepatitis B Virus (HBV), Hepatitis C virus (HCV) and Human Immunodeficiency Virus (HIV) infections can occur.

8p trinhthamhodang11 27-04-2021 9 1   Download