HER2 status

To evaluate the concordance between HER2 status in matched endoscopic biopsy and gastrectomy specimens of gastric adenocarcinoma patients. Patients and Methods: Fifty-five gastric adenocarcinoma patients were diagnosed by upper GI endoscopic biopsy and treated with gastrectomy. HER2 status was assessed by immunohistochemistry (IHC) and fluorescence in situ hybridisation (FISH) on both endoscopic biopsy and gastrectomy specimens.

7p vinatisu 29-08-2024 3 1   Download

Table 86-3 Suggested Approaches to Adjuvant Therapy Age Group h Lymp Endocr Tum tion Recommenda Node ine Receptor or (ER) Status Statusa Premenopa usal ve Positi Any Any Multidrug chemotherapy tamoxifen positive if + ER+ trastuzumab in HER- 2/neu tumors positive Premenopa usal ive Negat Any 2 Multidrug + ER+ cm, or 1–2 chemotherapy cm with tamoxifen if other poor positive prognostic trastuzumab in HERvariables 2/neu tumors positive Postmenopa usal ve Positi e Negativ Any Multidrug chemotherapy + trastuzumab in HER2/neu tumors positive Postmenopa usal ve Pos...

5p konheokonmummim 03-12-2010 311 3   Download