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Heterogeneous network
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Ccancer genomes accumulate a large number of passenger somatic mutations resulting from various endogenous and exogenous causes, including normal DNA damage and repair processes or cancer-related aberrations of DNA maintenance machinery as well as mutations triggered by carcinogenic exposures.
12p
vibransone
28-03-2024
3
2
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Systemic sclerosis (SSc) is a multi-organ autoimmune disease characterized by skin fibrosis. Internal organ involvement is heterogeneous. It is unknown whether disease mechanisms are common across all involved affected tissues or if each manifestation has a distinct underlying pathology.
24p
vioraclene
31-03-2024
6
2
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Synovial fibroblasts (SFs) are specialized cells of the synovium that provide nutrients and lubricants for the proper function of diarthrodial joints. Recent evidence appreciates the contribution of SF heterogeneity in arthritic pathologies. However, the normal SF profiles and the molecular networks that govern the transition from homeostatic to arthritic SF heterogeneity remain poorly defined.
25p
viellison
28-03-2024
7
2
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Novel immunotherapy combination therapies have improved outcomes for patients with hepatocellular carcinoma (HCC), but responses are limited to a subset of patients. Little is known about the inter- and intra-tumor heterogeneity in cellular signaling networks within the HCC tumor microenvironment (TME) that underlie responses to modern systemic therapy.
14p
vicwell
29-02-2024
6
2
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Type 2 diabetes (T2D) is a heterogeneous and polygenic disease. Previous studies have leveraged the highly polygenic and pleiotropic nature of T2D variants to partition the heterogeneity of T2D, in order to stratify patient risk and gain mechanistic insight. We expanded on these approaches by performing colocalization across GWAS traits while assessing the causality and directionality of genetic associations.
15p
vicwell
29-02-2024
3
1
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Ebook Network programming with windows sockets: Part 2 includes content: Chapter 9 design goals, chapter 10 CWinSock, chapter 11 CDatagramSocket, chapter 12 CStreamSocket, chapter 13 bringing it all together, chapter 14 sample applications using the class library, chapter 15 practical client/server database application, chapter 16 finger application in a heterogeneous UNIX Environment.
139p
longtimenosee03
22-02-2024
3
1
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The third generation (3G) of mobile networks introduces wide spectrum and high data rates as well as variety of circuit-switched and packet-based services. It provides IP connectivity besides the circuit switching. Future generation mobile systems are expected to include heterogeneous access technologies, such as wireless LAN and 3G, as well as end-to-end IP connectivity (i.e., an all-IP network). The diversity of traffic services and access technologies creates new possibilities for both operators and users. On the other hand, it raises new traffic and design issues.
385p
longtimenosee03
22-02-2024
6
2
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Ebook "Cancer systems biology: Methods and protocols" comprises protocols describing systems biology methodologies and computational tools, offering a variety of ways to analyze different types of high-throughput cancer data. Chapters give an overview over data types available in large-scale data repositories and state-of-the-art methods used in the field of cancer systems biology.
397p
lucchinguyen
28-12-2023
7
2
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In this paper, we consider the case where FMO map will be adapted to the MAC layer status to reduce the number of dropped packets. In other words, this work focuses on the generation of an explicit FMO map based on overflow state of queues at MAC layer.
8p
vijeff
01-12-2023
9
3
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Cholangiocarcinoma (CHOL) is the second most common primary hepatic malignant tumor, following hepatocellular carcinoma (HCC). CHOL is highly aggressive and heterogeneous resulting in poor prognosis.
13p
visharma
20-10-2023
7
2
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Nowadays, Software-defined Networking (SDN) is increasingly being deployed in network systems and by network operators due to its benefits, such as automation leading to excellent reliability, more efficient network management, cost-savings, and faster scalability. This paper proposes an LSTM-based link cost prediction for the server and route selection mechanism in a distributed and heterogeneous SDN network.
21p
vimulcahy
18-09-2023
8
4
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For better understanding the influence of heterogeneity of complex networks and quarantine treatment on epidemic spreading, we present a study on a fractional network-based epidemic model with fuzzy transmission.
15p
viberkshire
09-08-2023
8
4
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Facial emotion recognition (FER) is meaningful for human-machine interaction such as clinical practice, playing games, and behavioral description. FER has been an active area of research over the past few decades, and it is still challenging due to the high intra-class variation, the heterogeneity of human faces, and variations in images such as different facial poses and various lighting conditions.
7p
viannee
02-08-2023
7
4
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Scoring laboratory polysomnography (PSG) data remains a manual task of visually annotating 3 primary categories: sleep stages, sleep disordered breathing, and limb movements. Attempts to automate this process have been hampered by the complexity of PSG signals and physiological heterogeneity between patients.
8p
visteverogers
24-06-2023
6
2
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Investigating the molecular mechanisms of symptoms is a vital task in precision medicine to refine disease taxonomy and improve the personalized management of chronic diseases. Although there are abundant experimental studies and computational efforts to obtain the candidate genes of diseases, the identification of symptom genes is rarely addressed.
8p
visteverogers
24-06-2023
8
2
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When studying any specific rare disease, heterogeneity and scarcity of affected individuals has historically hindered investigators from discerning on what to focus to understand and diagnose a disease. New nongenomic methodologies must be developed that identify similarities in seemingly dissimilar conditions.
9p
vighostrider
25-05-2023
2
2
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Hydrogels have a complex, heterogeneous structure and organisation, making them promising candidates for advanced structural and cosmetics applications. Starch is an attractive material for producing hydrogels due to its low cost and biocompatibility, but the structural dynamics of polymer chains within starch hydrogels are not well understood, limiting their development and utilisation.
11p
viginny
30-12-2022
9
2
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This study investigated the impact of heterogeneity of crosslinking on a range of physical and mechanical properties of calcium alginate networks formed via external gelation with 0.25–2% sodium alginate and 2.5 and 5% CaCl2. Crosslinking in films with 1–2% alginate was highly heterogeneous, as indicated by their lower calcium content (35–7 mg Ca⋅g alginate− 1 ) and apparent solubility (5–6%).
8p
viginny
30-12-2022
12
2
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In the development of 5G mobile network, Fog computing becomes an emerging component of the Cloud computing paradigm as the 5G core to assure the diverse computational demands of IoT applications can be satisfied. A cloud-based application requires a combined use of cloud and local resources for its processing.
7p
viharry
15-12-2022
12
4
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Targeted therapies for Primary liver cancer (HCC) is limited to the multi-kinase inhibitors, and not fully effective due to the resistance to these agents because of the heterogeneous molecular nature of HCC developed during chronic liver disease stages and cirrhosis.
17p
viangelamerkel
27-07-2022
1
1
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