History of discovery

This history of antimicrobials is marked with impressive discoveries, the majority of which have their origin in natural products. However in this work, the antimicrobial activity of β- nitrostyrenes and related compounds of synthetic origin is reviewed and investigated with a particular focus on the influence of fluorine functionality. Various fluorinated β-methyl-β-nitrostyrene compounds were prepared, their minimum inhibition concentration in cultures of Gram positive, Gram negative and a fungus and their lipophilicity was determined.

133p runthenight05 01-03-2023 6 3   Download

Thebandccrystallins are evolutionarily related families of proteins that make up a large part of the refractive structure of the vertebrate eye lens. Each family has a distinctive gene structure that reflects a history of succes-sive gene duplications. A survey ofc-crystallins expressed in mammal, rep-tile, bird and fish species (particularly in the zebrafish, Danio rerio) has led to the discovery of cN-crystallin, an evolutionary bridge between theband cfamilies.

16p awards 06-04-2013 39 2   Download