Hydrophilic characteristic

Natural polymer-based nanofibers with functions of loading and releasing bioactive cues or drugs have recently gained interest for biomedical applications. Nanotopography and large surface area to volume ratio of hydrophilic polymer fibers promote their use as carriers of hydrophilic drugs.

8p viberbers 09-08-2023 7 4   Download

This paper presents the preparation and characterization of carrageenan/chitosan particles loading αmangostin - an active compound extracted from mangosteen fruit peels. The carrageenan/chitosan/α-mangostin particles were prepared by ionic gelation method in the presence of sodium tripolyphosphate as a cross-linking agent and potassium chloride as a gel agent.

13p vidudley 20-02-2023 2 2   Download

Most of hydrophilic and hydrophobic residues are thought to be exposed and buried in proteins, respectively. In contrast to the majority of the existing studies on protein folding characteristics using protein structures, in this study, our aim was to design predictors for estimating relative solvent accessibility (RSA) of amino acid residues to discover protein folding characteristics from sequences.

12p vioklahoma2711 19-11-2020 6 1   Download

Two commercially available microneedle rollers with a needle length of 200 μm and 300 μm were selected to examine the influence of microneedle pretreatment on the percutaneous permeation of four non-steroidal anti-inflammatory drugs (diclofenac, ibuprofen, ketoprofen, paracetamol) with different physicochemical drug characteristics in Franz-type diffusion cells.

7p viorochimaru2711 30-05-2020 23 1   Download

The current study focuses on designing biodegradable transferosomal hydrogel using lignans and bio surfactant for transdermal applications. In the study, the lignans concentrate (LC) was extracted from flaxseeds and used to prepare vesicular transferosomes/transferosomal hydrogel by thin film hydration technique for drug delivery. The resultant formulations were characterized using light microscopy, DLS, Zeta potential, entrapment efficiency (EE %) and stability. In vitro skin permeation studies were also performed. The synthesized transferosomes were spherical in shape.

9p cothumenhmong1 08-12-2019 12 1   Download

Hydrogel products constitute a group of polymeric materials, the hydrophilic structure of which renders them capable of holding large amounts of water in their three-dimensional networks. Extensive employment of these products in a number of industrial and environmental areas of application is considered to be of prime importance. As expected, natural hydrogels were gradually replaced by synthetic types due to their higher water absorption capacity, long service life, and wide varieties of raw chemical resources.

17p trinhthamhodang1 16-11-2019 19 1   Download