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Immunomodulatory potential
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Ebook "Perinatal tissue-derived stem cells: Alternative sources of fetal stem cells" covers several aspects of perinatal tissue-derived stem cells, from theoretical concepts to clinical applications. Topics include functions and different sources, immunomodulatory properties, translational point of view, GMP facility design and manufacturing for clinical translation, therapeutic potentials, and finally ethical considerations.
246p
tracanhphuonghoa1007
22-04-2024
3
2
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The linkage between IDO2 expression and cancer progression is still unclear, particularly in medullary thyroid carcinoma (MTC). Our purpose is to unveil the potential correlations between IDO2 status, clinicalpathological parameters, patients’ prognosis, and the possible immunomodulatory functions in MTC.
15p
vileonardodavinci
23-12-2023
5
3
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RNASET2 has been identified as an oncogene with anti-angiogenic and immunomodulatory effects in a variety of cancers, but its function in clear cell renal cell carcinoma (ccRCC) is still not well understood.
16p
vioracle
29-09-2023
5
2
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Mesenchymal stem cells (MSCs) have become an effective tool for treating immune-related diseases due to their multilineage potential and immunomodulatory capabilities. One of the main factors contributing to their immunomodulatory capabilities is the IDO cascade, which was chosen as the main subject in this research.
5p
vimulcahy
18-09-2023
4
3
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Our previous study demonstrated that plant extract-based diets of E. hirta and P. guajava were effective to stimulate immune responses in striped catfish (P. hypophthalmus). Therefore, in this study, we investigated the chemical investigation as well as the immunomodulatory potential of some isolated compounds from E. hirta and P. guajava.
8p
vidoctorstrange
06-05-2023
3
1
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Banana (Musa acuminata and M. acuminata x M. balbisiana)fruit cell walls are rich inmannans, homogalacturonans and xylogalacturonan, rhamnogalacturonan-I, and arabinogalactans, certain forms of which is considered to have immunomodulatory activity.
11p
vihermione
06-01-2023
6
3
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Adjuvants are substances that increase the immune response to a given antigen. In the development of novel vaccine adjuvants/ systems, saponins are one of the most attractive molecules due to their altered immunomodulatory activities. In this study, we tried to develop PEG (polyethylene glycol)/cholesterol-based lipid nanoparticles (LNPs) to deliver the Astragaloside VII (AST-VII) and potentiate adjuvant properties of AST-VII for the influenza vaccine.
11p
thiencuuchu
27-11-2021
7
1
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The objectives of the thesis: The objectives of this study are to investigate the main chemical compositions of Euphorbia hirta L. to search for chemical constituents in relation to biological activities, contributing to further studies to create products for application in the aquarculture industry in particular and for life in general.
31p
extraenglish
24-05-2021
27
3
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Vitamin D displays immunomodulatory activities and has been proposed as a potential player in the pathogenesis of rheumatoid arthritis (RA). A negative association between serum 25(OH) vitamin D levels and RA activity was demonstrated but longitudinal studies investigating the role of vitamin D levels in predicting RA activity and response to treatment are lacking.
8p
vianttinic2711
20-04-2021
11
1
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Vitamin D is well known for its function in calcium homeostasis and bone mineralisation, but is increasingly studied for its potential immunomodulatory properties. Vitamin D deficiency is a common problem in patients with COPD.
9p
vimontana2711
05-04-2021
10
2
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The objectives of this study are to investigate the main chemical compositions of Euphorbia hirta L. to search for chemical constituents in relation to biological activities, contributing to further studies to create products for application in the aquarculture industry in particular and for life in general.
31p
capheviahe27
23-02-2021
25
3
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The increasing incidence and poor outcome associated with malignant pleural effusion (MPE) requires finding an effective treatment for this disease. Inhibitory B7-H4 is expressed in many different human cancers but its role in malignant pleural tissue has yet to be established.
6p
vimanama2711
30-07-2020
8
2
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Fusaruside is an immunomodulatory fungal sphingolipid which has medical potentials for treating colitis and liver injury, but its poor natural abundance limits its further study.
9p
vihamax2711
21-04-2020
8
0
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Antibiotic-resistant pathogens are an emerging threat in this century. Epinecidin-1 is a multifunctional Antimicrobial Peptide (AMP) produced by Orange-spotted grouper (Epinephelus coioides) has been shown to have extensive potentials as an alternative for current antibiotics.
11p
vimax2711
27-03-2020
8
0
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Cathelicidins are an important family of cationic host defense peptides in vertebrates with both antimicrobial and immunomodulatory activities. Fowlicidin-1 and fowlicidin-2 are two newly identified chicken cathelicidins with potent antibacterial activities. Here we report structural and func-tional characterization of the putatively mature form of the third chicken cathelicidin, fowlicidin-3, for exploration of its therapeutic potential.
11p
inspiron33
23-03-2013
39
2
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Highway spending, however, is not the only area where money is allocated in this fashion. According to the Congressional Research Service, the nation’s 20 busiest ports handle 80 percent of arriving oceangoing ships but account for less than 40 percent of federal Harbor Maintenance Trust Fund expenditures. 20 In the alloca- tion of funds for drinking water projects, millions of dollars are allotted every year just to ensure that every state receives at least 1 percent of the funds available.
56p
enterroi
02-02-2013
48
3
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Pulmonary embolism is a serious, potentially life-threatening cardiopulmonary disease that occurs due to partial or total obstruction of the pulmonary arterial bed. Pulmonary embolism constitutes 5-25% of in-hospital deaths, and mortality is decreased from 30% to 8% with early treatment. Therefore, risk factors should be identified and treatment should be planned to decrease the risk of mortality. Clinical findings, routine laboratory data, electrocardiogram, chest X-ray, and arterial blood gases are not sufficient to diagnose or rule out pulmonary embolus.
246p
wqwqwqwqwq
21-07-2012
92
13
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There is an urgent need to develop new innovative therapies for the control of advanced cancer. The combination of antigen-specific immunotherapy with the employment of immunomodulatory agents has emerged as a potentially plausible approach for the control of advanced cancer. Methods: In the current study, we explored the combination of the DNA vaccine encoding calreticulin (CRT) linked to human papillomavirus type 16 (HPV-16) E7 antigen (CRT/E7) with the TLR7 agonist imiquimod for their ability to generate E7-specific immune responses and antitumor effects in tumor-bearing mice.
9p
toshiba23
18-11-2011
57
4
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This chapter provides a brief overview of the immune response as background for understanding the mechanism of action of immunomodulatory agents. The general principles of pharmacological immunosuppression are discussed in the context of potential targets, major indications, and unwanted side effects.
26p
vanass
01-04-2011
67
8
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