Inducible clindamycin resistance
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The present study was conducted for detection of inducible resistance to Clindamycin in Staphylococcus aureus isolates using D – test at Raichur Institute of Medical Sciences-teaching hospital, RAICHUR, Karnataka, India.
6p gaocaolon9 22-12-2020 22 1 Download
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Staphylococcus aureus is one of the most common organisms causing nosocomial and community acquired infections worldwide. Antibiotic resistance in this organism has become an ever-increasing problem. Present study was undertaken to determine the percentage of Staphylococcus aureus isolates having inducible clindamycin resistance. A total of 270 Staphylococcus aureus isolated from different specimens were subjected to routine antibiotic sensitivity testing by Kirby Bauer disc diffusion method.
8p trinhthamhodang6 09-07-2020 12 1 Download
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Staphylococcus aureus causes skin and soft tissue infections (SSTIs), if not treated with proper antimicrobials can leads to serious form of infection. Multi-drug resistant strains left us very few therapeutic alternatives, in such cases clindamycin can be a good option with true sensitivity. The clinical samples exhibiting skin and soft tissue infection received in the department of microbiology further subjected to isolation of Staphylococcus aureus. Isolated strains further subjected to D-test to detect inducible clindamycin resistant strains as per standard guidelines.
8p nguathienthan5 04-06-2020 14 0 Download
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The increasing resistance to many antimicrobial agents is seen in Staphylococcus aureus in all healthcare facilities. The commonest antibiotic for the treatment of the Methicillin and multi drug resistant Staphylococcal infections is clindamycin. Emergence of these resistances in Staphylococcus aureus has resulted in failure of clindamycin therapy. A total 220 Nasal swabs from healthy persons were collected and processed by standard microbiological procedures.
9p angicungduoc4 26-04-2020 8 0 Download
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Clindamycin is a substitute choice for mild to moderate Staphylococcal infections especially in penicillin-allergic patients. Staphylococcus aureus is one of the most common pathogen with ability to cause wide range of infections in humans. Clindamycin has been used to treat serious infections for more than 30 years in children. It remains effective for many infections caused by community-acquired and hospital acquired methicillin-resistant Staphylococcus aureus (CA-MRSA/ HA- MRSA).
5p trinhthamhodang4 22-03-2020 10 1 Download
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Coagulase-negative Staphylococci (CoNS) have emerged as predominant pathogens in hospital and community acquired infections. Clindamycin is a good therapeutic agent in treatment of skin, soft tissue as well as serious infections caused by both methicillin sensitive and resistant Staphylococci. However, strains with inducible clindamycin resistance often lead to therapeutic failure. Hence, each laboratory should be aware of the local prevalence of this resistance among clinical staphylococcal isolates.
10p cothumenhmong4 25-03-2020 10 0 Download
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The study was done to note the presence of MRSA and Inducible resistance to Clindamycin in various samples of the Staphylococcus aureus from the Hospital.
6p nguaconbaynhay4 22-03-2020 7 1 Download
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To demonstrate inducible clindamycin resistance among the staphylococcal isolates from various clinical samples by D- test. A total of 125 Staphylococcus aureus and Coagulase Negative Staphylococcus (CONS) isolates were collected from clinical samples. All the samples were tested for inducible clindamycin resistance by using the D -test as per CLSI guidelines.
6p chauchaungayxua3 07-02-2020 13 0 Download
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Staphylococcus aureus is a versatile human pathogen causing infections ranging from relatively mild skin and soft tissue infection to life threatening sepsis, pneumonia and toxic shock syndrome. The increasing incidence of a variety of infections and, especially, the expanding role of community-associated methicillin-resistant S. aureus (MRSA)--has led to emphasis on the need for safe and effective agents to treat both systemic and localized staphylococcal infections. Clindamycin is considered to be one of the alternative agents in these infections.
10p nguathienthan2 26-12-2019 38 0 Download
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This study was completed to know the prevalence of Methicillin-Susceptible (MSSA) and Methicillin-Resistant S. aureus (MRSA) in swab samples from retail meat shops (RM) and customers (CU) in five districts of Punjab, India. An aggregate of 182 swabs samples was aseptically collected from RM shops and customers. The collected samples were processed for an isolation of S. aureus isolates. The phenotypic resistance of S. aureus isolates was most noteworthy to Penicillin (PEN, 97.83%) trailed by Ciprofloxacin (CPH, 56.52%), Tetracycline (TET, 36.96%), Trimethoprim-Sulfamethoxazole (TSH, 34.
11p quenchua2 15-12-2019 20 2 Download
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Very few therapeutic options are available from the time of emergence of MRSA. Macrolide lincosamide streptogramin B (MSLB) antibiotics can be used in such scenarios with clindamycin being the preferred agent due to its excellent pharmacokinetic properties. Staphylococcal resistance to clindamycin may be inducible (iMLSB - inducible MacrolideLincosamide Streptogramin B resistance) or constitutive. The treatment of patients harbouring iMLSB Staphylococci with clindamycin leads to the development of constitutive resistance, subsequently leading to therapeutic failure.
8p kequaidan2 13-12-2019 30 0 Download