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Inhibition mechanism prediction
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A coagulation cascade forms through proteolytic reactions and involves different factors. There are two coagulation pathways, including intrinsic and extrinsic mechanisms, which converge by the formation of factor Xa. Factor Xa plays a crucial role in the formation of the complex with factor Va in the presence of calcium ions and phospholipids. This complex converts prothrombin to thrombin, which leads to the formation of a very strong fibrin clot.
6p
kethamoi7
15-08-2020
15
1
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Design and synthesis of pyrazole-dimedone derivatives were described by one-pot multicomponent reaction as new antimicrobial agents. These new molecular framework were synthesized in high yields with a broad substrate scope under benign conditions mediated by diethylamine (NHEt2).
13p
vijiraiya2711
27-05-2020
9
0
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The ignition delay times of methane/air mixture diluted by N2 and CO2 were experimentally measured in a chemical shock tube. The experiments were performed over the temperature range of 1300–2100 K, pressure range of 0.1–1.0 MPa, equivalence ratio range of 0.5–2.0 and for the dilution coefficients of 0%, 20% and 50%. The results suggest that a linear relationship exists between the reciprocal of temperature and the logarithm of the ignition delay times. Meanwhile, with ignition temperature and pressure increasing, the measured ignition delay times of methane/air mixture are decreasing.
13p
trinhthamhodang1
16-11-2019
24
1
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The major disadvantage of the Greacen et al. (1968) model is that it requires many laborious measurements of soil mechanical properties. A simpler approach was adopted by Romkens & Miller (1971), who equated the pressure required for void-ratio changes occurring in a cylinder of soil around a root with the pressure required for one-dimensional soil consolidation. The resulting equation was used to predict the rooting densities at which further root radial expansion would be inhibited by the expansion of neighbouring roots.
43p
loixinloi
08-05-2013
40
4
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