![](images/graphics/blank.gif)
Investigate clinical outcomes
-
The study was conducted to investigate the clinical outcomes and mortality risk factors related to Staphylococcus aureus pneumonia in patients with and without diabetes mellitus (DM). This was a case-control study on 118 patients with S. aureus pneumonia hospitalized between April 2021 and May 2023.
8p
vikoch
27-06-2024
1
1
Download
-
Multiple studies have indicated that patients with high body mass index (BMI) may have favourable survival outcomes following treatment with an immune checkpoint inhibitor (ICI). However, this evidence is limited by several factors, notably the minimal evidence from randomised controlled trials (RCTs), the use of categorised BMI with inconsistent cut point definitions, and minimal investigation of contemporary combination ICI therapy.
8p
vishanshan
27-06-2024
1
1
Download
-
This study aimed to investigate the characteristics and clinical outcomes in a series of patients with extremity soft tissue sarcoma (STS) who underwent amputation at a large East Asian referral center.
9p
vishanshan
27-06-2024
1
1
Download
-
The impact of tumor-infiltrating neutrophils (TINs) on clinical outcomes has been reported in various cancer types, but their role in hepatocellular carcinoma (HCC) has not been fully evaluated. The aim of this study was to investigate the prognostic values for TINs in HCC patients undergoing curative resection.
8p
vishanshan
27-06-2024
1
1
Download
-
This study aimed to identify new pyroptosis-associated tumor antigens for use in mRNA vaccines and the screening of sensitive LUAD populations suitable for vaccination. The association between tumor immune infiltrating cell abundance and potential tumor antigens was investigated and visualized using the analysis modules of gene expression, clinical outcomes, and somatic copy number variation.
15p
vishanshan
27-06-2024
2
1
Download
-
In the context of breast cancer (BC), the correlation between lymphocytes and clinical outcomes, along with treatment response, has garnered attention. Despite this, few investigations have delved into the interplay among distinct peripheral blood lymphocyte (PBL) types, immune attributes, and their clinical implications within the BC landscape.
10p
vikoch
27-06-2024
1
1
Download
-
This clinical report investigates the role of D-dimer in young ischemic stroke patients and its association with stroke severity assessed by the National Institutes of Health Stroke Scale (NIHSS) and functional outcomes evaluated using the modified Rankin Scale (mRS).
6p
vilarry
12-03-2024
3
1
Download
-
To investigate the expression of programmed death ligand-1 (PD-L1) and the levels of CD8+ tumor-infiltrating lymphocytes (TILs) in meningioma as well as determine the association between their levels and the clinical outcomes.
11p
vileonardodavinci
23-12-2023
3
2
Download
-
The aim of the study is to investigate the clinical features and surgical outcomes of ureteral reconstruction during primary, interval and secondary cytoreductive surgery for ovarian cancer.
9p
vileonardodavinci
23-12-2023
2
2
Download
-
Recent studies have shown a lower likelihood of locoregional recurrences in patients with a low 21-gene recurrence score (RS). In this single-institution study, we investigated whether there are any associations between different cutoff values of 21-gene RS, histopathological factors, and outcomes in patients with long-term follow-up.
9p
vileonardodavinci
23-12-2023
5
2
Download
-
The KMT2A gene, formerly named the MLL gene, is rearranged (KMT2Ar) in 70–75% of infants, 5–6% of children and 10–15% of adult patients with B cell acute lymphoblastic leukemia (B-ALL). The outcome after chemotherapy of pediatric cases remains poor, and only a few studies have investigated the clinical and laboratory features, treatment response and prognosis in Chinese populations.
11p
vileonardodavinci
23-12-2023
6
3
Download
-
The aim of this study was to investigate the influence of serum iron levels in advanced gastric cancer (GC) patients treated with programmed cell death protein-1 (PD-1) inhibitors. We retrospectively reviewed 149 GC patients who were treated with PD-1 inhibitors at our center. Clinicopathological characteristics, laboratory data, and clinical outcomes were analyzed.
10p
vileonardodavinci
23-12-2023
6
2
Download
-
The influence factors associated with mechanical thrombectomy for patients with acute large vessel occlusion stroke remain to be elucidated. This study aimed to investigate clinical and procedural factors influence on good outcome and mortality after mechanical thrombectomy in a cohort of patients stroke.
8p
visoros
01-11-2023
3
1
Download
-
To investigate whether a combination of 0.5mg avodart plus 4mg doxazosin is more effective than 4mg doxazosin alone in treatment‐naïve men with moderately to severe symptomatic benign prostatic hyperplasia (BPH) at risk of progression.
8p
visoros
01-11-2023
2
1
Download
-
Nanoliposomal irinotecan plus fluorouracil/leucovorin (5-FU/LV) is a standard second-line therapy for patients with pancreatic cancer. Identification of biomarkers is important to determine appropriate treatment strategies. We investigated the clinical practice outcomes and biomarkers associated with the nanoliposomal irinotecan plus 5-FU/LV regimen.
8p
vischultz
20-10-2023
3
1
Download
-
As a consequence of effective treatment procedures, the number of long-term survivors of colorectal cancer is ever increasing. Adopting the method of a previous study on breast cancer patients, the goal of the present research was to investigate colorectal cancer patients’ recollections of their illness and treatment experiences up to seven years after they have been enrolled in a randomised controlled clinical trial on the direct improvement of quality of life (RCT DIQOL).
13p
vischultz
20-10-2023
3
2
Download
-
In this study, we aimed to investigate the effects of hyperlipidemia treatment at the time of breast cancer diagnosis and to examine its correlation with metastasis to axillary lymph nodes among patients with so-called cT1 breast cancer whose primary lesion was 2 cm or less and was pathologically evaluated by sentinel lymph node biopsy or axillary lymph node dissection.
14p
vischultz
20-10-2023
3
1
Download
-
Cuproptosis is a regulated cell death form associated with tumor progression, clinical outcomes, and immune response. However, the role of cuproptosis in pancreatic adenocarcinoma (PAAD) remains unclear. This study aims to investigate the implications of cuproptosis-related genes (CRGs) in PAAD by integrated bioinformatic methods and clinical validation.
18p
visharma
20-10-2023
5
3
Download
-
Uterine sarcoma is an uncommon aggressive malignancy. Optimal management and prognostic factors have yet to be well recognized due to their rarity and various histological subtypes. This study aims to investigate these patients’ prognostic factors, treatment modalities, and oncological outcomes.
13p
visharma
20-10-2023
4
2
Download
-
High leukocyte mitochondrial DNA copy number contributes to poor prognosis in breast cancer patients
Compelling evidence has indicated a significant association between leukocyte mitochondrial DNA copy number (mtDNAcn) and prognosis of several malignancies in a cancer-specific manner. However, whether leukocyte mtDNAcn can predict the clinical outcome of breast cancer (BC) patients has not been well investigated
10p
visharma
20-10-2023
4
2
Download
CHỦ ĐỀ BẠN MUỐN TÌM
![](images/graphics/blank.gif)