Karyotype evolution
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Liquid biopsies and the dynamic tracking of somatic mutations within circulating tumour DNA (ctDNA) can provide insight into the dynamics of cancer evolution and the intra-tumour heterogeneity that fuels treatment resistance. However, identifying and tracking dynamic changes in somatic copy number alterations (SCNAs), which have been associated with poor outcome and metastasis, using ctDNA is challenging.
15p vicwell 29-02-2024 6 1 Download
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Part2 book "Equine genomics" includes content: Genomics of skin disorders, genomics of muscle disorders, genomics of skeletal disorders, genomics of reproduction and fertility, genetics of equine neurologic disease, molecular genetic testing and karyotyping in the horse, genomics of laminitis, genomics of performance, genomics of the circadian clock, mitochondrial genome - Clues about the evolution of extant equids and genomic diversity of horse breeds.
178p oursky04 14-09-2023 4 2 Download
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Pronghorn (Antilocapridae, 2n = 58) and saola (Bovidae, 2n = 50) are members of Pecora, a highly diversified group of even-toed hoofed mammals. Karyotypes of these species were not involved in chromosome painting studies despite their intriguing phylogenetic positions in Pecora.
8p vinarcissa 21-03-2023 2 1 Download
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Reconstruction of ancestral karyotypes is critical for our understanding of genome evolution, allowing for the identification of the gross changes that shaped extant genomes. The identification of such changes and their time of occurrence can shed light on the biology of each species, clade and their evolutionary history.
16p vigalileogalilei 27-02-2022 17 1 Download
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Brassicaceae is a family of green plants of high scientific and economic interest, including thale cress (Arabidopsis thaliana), cruciferous vegetables (cabbages) and rapeseed. Results: We reconstruct an evolutionary framework of Brassicaceae composed of high-resolution ancestral karyotypes using the genomes of modern A. thaliana, Arabidopsis lyrata, Capsella rubella, Brassica rapa and Thellungiella parvula.
17p viaristotle 29-01-2022 16 0 Download
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Chromosomal data can provide very valuable information about karyotypic phylogeny and speciation. This is the first study on karyotype phylogeny and polyploidy variations of the genus Paronychia.
10p tudichquannguyet 29-11-2021 18 2 Download
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Chromosomal data are valuable and very useful for revealing evolution and speciation processes. Due to its wide distribution throughout the world, morphological differences, and chromosomal alterations, Erodium L’Hér. is an important genus for investigating the relationship between chromosomal alterations and karyotype evolution. In the present study, the chromosome records of 15 taxa are provided; three are reported here for the first time (E. birandianum, E. gaillardotii, and E. hendrikii), seven present new chromosome numbers, and five are in agreement with previous reports.
14p tudichquannguyet 29-11-2021 14 1 Download
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Malaria mosquitoes have had a remarkable stability in the number of chromosomes in their karyotype (2n = 6) during 100 million years of evolution. Moreover, autosomal arms were assumed to maintain their integrity even if their associations with each other changed via whole-arm translocations. Here we use high-coverage comparative physical genome mapping of three Anopheles species to test the extent of evolutionary conservation of chromosomal arms in malaria mosquitoes.
14p vibeauty 23-10-2021 20 2 Download
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Solea senegalensis (Kaup, 1858) is a commercially important flatfish species, belonging to the Pleuronectiformes order. The taxonomy of this group has long been controversial, and the karyotype of the order presents a high degree of variability in diploid number, derived from chromosomal rearrangements such as Robertsonian fusions. Previously it has been proposed that the large metacentric chromosome of S. senegalensis arises from this kind of chromosome rearrangement and that this is a proto-sex chromosome.
11p vitzuyu2711 29-09-2021 7 1 Download
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Arachis contains 80 species that carry many beneficial genes that can be utilized in the genetic improvement of peanut (Arachis hypogaea L. 2n = 4x = 40, genome AABB). Chromosome engineering is a powerful technique by which these genes can be transferred and utilized in cultivated peanut.
14p vishikamaru2711 29-04-2020 10 2 Download
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Chapter 13 - Chromosomal rearrangements and changes in chromosome number. This chapter presents the following content: Rearrangements of DNA sequences, transposable genetic elements, rearrangements and evolution: a speculative comprehensive example, changes in chromosome number, emergent technologies: beyond the karyotype.
89p tangtuy04 12-03-2016 51 5 Download