Macrocyclic derivatives

Comparison between the calculated and experimental results covering molecular structures, assignment of fundamental vibrational modes, and thermodynamic properties were investigated. The optimized molecular geometries were compared with the experimental data obtained from X-ray data of a similar complex, which indicated that the theoretical results agree with the corresponding experimental values. The UV-Vis spectrum of the compound was also recorded and some properties, such as HOMO and LUMO energies and λmax , were determined using DFT (PW91) method.

12p langthannam 29-12-2021 18 0   Download

New phthalocyanine compounds containing mixed-donor substituted macrocyclic groups were synthesized. The complexes of metal phthalocyanines 3–5 were prepared by the reaction of 2 to get dinitrile derivative complexes by means of the corresponding anhydrous metal salts. Structures of the new compounds were characterized by IR, 1H NMR, 13C NMR, elemental analysis, and MS spectral data.

11p langthannam 29-12-2021 8 0   Download

Metal-free phthalocyanine 3 and its metallophthalocyanine derivatives 4, 5, and 6 (M = Zn, Co, and Ni) substituted with four 21-membered pentathiadiaza macrocycles were synthesized and their structures identified by elemental analysis, IR, 1 H NMR, mass, and UV-Vis spectroscopy techniques. The aggregation properties of phthalocyanines 4, 5, and 6 were investigated in different solvents and at different concentrations of dimethylformamide.

10p langthannam 29-12-2021 5 0   Download

Cyclodextrins (CDs) are natural, nontoxic, and biodegradable macrocyclic oligosaccharides. As supramolecular hosts, CDs have numerous applications in many aspects. However, nonsubstituted CDs have the disadvantages of solubility, unspecific recognition sites, and weak interactions with guest molecules. Therefore, new CD-based derivatives are successfully designed, synthesized, and widely used in various fields. This contribution outlines the research progress in CD derivatives.

18p tudichquannguyet 29-11-2021 9 0   Download

Identification of new drugs against paediatric sarcomas represents an urgent clinical need that mainly relies on public investments due to the rarity of these diseases. In this paper we evaluated the in vitro and in vivo efficacy of a new maltol derived molecule (maltonis), belonging to the family of molecules named hydroxypyrones.

14p virose2711 25-09-2020 19 1   Download