Magic pipeline

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MaGIC: A machine learning tool set and web application for monoallelic gene inference from chromatin

A large fraction of human and mouse autosomal genes are subject to random monoallelic expression (MAE), an epigenetic mechanism characterized by allele-specific gene expression that varies between clonal cell lineages. MAE is highly cell-type specific and mapping it in a large number of cell and tissue types can provide insight into its biological function. Its detection, however, remains challenging.

5p vicoachella2711 27-10-2020 8 0 Download

Magic-BLAST, an accurate RNA-seq aligner for long and short reads

Next-generation sequencing technologies can produce tens of millions of reads, often paired-end, from transcripts or genomes. But few programs can align RNA on the genome and accurately discover introns, especially with long reads. We introduce Magic-BLAST, a new aligner based on ideas from the Magic pipeline.

19p vicolorado2711 23-10-2020 14 0 Download