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Mammalian embryos
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Ebook "Nuclear reprogramming and stem cells" provides a timely glimpse into the methods that have been developed to instigate, and the mechanisms that have been identified to drive, the process of nuclear reprogramming, chronicling how the field has developed over the last 50-60 years. Nuclear Reprogramming and Stem Cells will serve as a valuable resource for all researchers in the field of stem cell biology, including those just setting out on their career path as well as those already established in the field.
340p
ladongphongthanh1008
22-04-2024
3
2
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Ebook "Zygotic genome activation: Methods and protocols" provides an overview of zygotic genome activation (ZGA) and the use of recent tools to elucidate the events that occur during ZGA. The chapters in this book cover topics such as: clearance of maternal RNAs, detection of miRNA in mammalian oocytes and embryos, RNA FISH to study ZGA in early mouse embryos, and CRISPR/Cas9-mediated gene targeting during embryogenesis in the mouse and pig.
271p
lucchinguyen
28-12-2023
5
2
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Part 1 book "Cell death in mammalian ovary" includes content: Brief description of the histological, cytological and functional aspects of the ovary; embryonic development of the ovary, sexual reproduction and meiosis; development of the ovary in the embryo, infancy, childhood, pre puberty and puberty; apoptosis, autophagy, oncosis, necrosis.
125p
muasambanhan01
11-12-2023
4
2
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X chromosome inactivation (XCI) is that one of two chromosomes in mammalian females is silenced during early development of embryos. There has been a statistical measure for the degree of the skewness of XCI for qualitative traits. However, no method is available for such task at quantitative trait loci.
17p
vihagrid
30-01-2023
7
3
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Transposable elements (TEs) are notable drivers of genetic innovation. Over evolutionary time, TE insertions can supply new promoter, enhancer, and insulator elements to protein-coding genes and establish novel, species-specific gene regulatory networks.
17p
viaristotle
29-01-2022
8
0
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During mammalian early embryogenesis, expression and epigenetic heterogeneity emerge before the first cell fate determination, but the programs causing such determinate heterogeneity are largely unexplored.
23p
viarchimedes
26-01-2022
4
0
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Assisted reproductive technologies (ART) are widely used to treat fertility issues in humans and for the production of embryos in mammalian livestock. The use of these techniques, however, is not without consequence as they are often associated with inauspicious pre- and postnatal outcomes including premature birth, intrauterine growth restriction and increased incidence of epigenetic disorders in human and large offspring syndrome in cattle.
15p
vibeauty
23-10-2021
11
1
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MicroRNAs (miRNAs) are small noncoding RNAs that act as post-transcriptional regulators of gene targets. Accurate quantification of miRNA expression using validated internal controls should aid in the understanding of their role in epigenetic modification of genome function.
10p
viwyoming2711
16-12-2020
11
1
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Sex determination in mammals requires expression of the Y-linked gene Sry in the bipotential genital ridges of the XY embryo. Even minor delay of the onset of Sry expression can result in XY sex reversal, highlighting the need for accurate gene regulation during sex determination.
14p
viwyoming2711
16-12-2020
11
0
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Super-resolution fluorescence microscopy performed via 3D structured illumination microscopy (3D-SIM) is well established on flat, adherent cells. However, blastomeres of mammalian embryos are non-adherent, round and large. Scanning whole mount mammalian embryos with 3D-SIM is prone to failure due to the movement during scanning and the large distance to the cover glass.
15p
viwyoming2711
16-12-2020
10
1
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Wnt11 is a member of the Wnt family of secreted signals controlling the early steps in ureteric bud (UB) branching. Due to the reported lethality of Wnt11 knockout embryos in utero, its role in later mammalian kidney organogenesis remains open.
14p
viwyoming2711
16-12-2020
9
1
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Pluripotency defines the propensity of a cell to differentiate into, and generate, all somatic, as well as germ cells. The epiblast of the early mammalian embryo is the founder population of all germ layer derivatives and thus represents the bona fide in vivo pluripotent cell population.
20p
viwyoming2711
16-12-2020
8
1
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The segregation of the hypoblast and the emergence of the pluripotent epiblast mark the final stages of blastocyst formation in mammalian embryos. In bovine embryos the formation of the hypoblast has been partially studied, and evidence shows that MEK signalling plays a limited role in the segregation of this lineage.
13p
viwyoming2711
16-12-2020
7
1
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Mammalian early embryo development requires a well-orchestrated interplay of cell signaling pathways. Notch is a major regulatory pathway involved in cell-fate determination in embryonic and adult scenarios. However, the role of Notch in embryonic pre-implantation development is controversial.
16p
viwyoming2711
16-12-2020
13
1
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Embryonic diapause is a phenomenon characterized by the temporary suspension of embryo development and delayed implantation in the uterus. It is an interesting reproductive strategy that has been frequently exploited across the animal kingdom. Mammalian embryonic diapause is categorized as obligate and facultative and broadly divided into three phases: entry into diapause, maintenance and termination of diapause. Obligate diapause occurs in every gestation of some species, while facultative diapause occurs in others, associated with metabolic stress, usually lactation.
9p
caygaocaolon3
09-03-2020
11
1
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Parthenogenetically derived mammalian embryos, with no paternal genome, are not viable and die, largely from defective placental growth attributed to a lack of paternal effect, resulting in the low blastulation rate and low derivation efficiency of parthenogenetic embryonic stem cells (pESCs).
11p
nutifooddau
27-01-2019
20
2
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The male seahorse incubates its young in a manner resembling that of a mammalian pregnancy. After the female deposits her eggs into the male’s brood pouch they are fertilized and the embryos develop and grow for several weeks until they are able to withstand the external environmental conditions independently, at which point they are irreversibly released. Although the precise function of the brood pouch is not clear, it is probably related to pro-viding a suitable protective and osmotic environment for the young. ...
15p
awards
06-04-2013
27
2
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The mammalian preimplantation embryo is a critical and unique stage in embryonic development. This stage includes a series of crucial events: the transition from oocyte to embryo, the first cell divisions, and the establish-ment of cellular contacts.
11p
media19
04-03-2013
35
1
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Mitochondria isolated from embryos of the crustaceanArtemia franciscana lack the Ca 2+ -induced permeability transition pore. Although the composi-tion of the pore described in mammalian mitochondria is unknown, the impacts of several effectors of the adenine nucleotide translocase (ANT) on pore opening are firmly established.
15p
mobifone23
08-01-2013
39
3
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