Measles virus infection

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Serological Survey of measles virus among children 0 – 12 years of age was carried out in some States in North Western Nigeria. A total of 450 blood samples were collected and analyzed for measles virus IgM and IgG using commercial Elisa kit Obtained from Diagnostic Automation/ Cortez Diagnostics, California, the results was interpreted according to the manufacturer’s instruction.

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Molecular characterization of measles virus among children in parts of north western Nigeria, out of 30 samples analysed for PCR with specific primers, 21 samples confirmed presence of measles virus infection. Genotype B3 strain was confirmed in four (4) samples selected from different location within the state in Northern Western Nigeria. Sokoto, Jigwa and Kaduna States, Ten (10) IgM positive samples from each States were randomly selected and subjected to RT PCR, out of the ten (10) IgM positive samples from each state.

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In pediatric sarcomas, outcomes of established therapies still remain poor, especially due to highgrade resistances to chemotherapeutic compounds. Taking novel biological approaches into account, virotherapy was found to be efficient in many pediatric sarcoma types.

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Measles, an acute viral illness caused by a virus belonging to the family Paramyxoviridae, is a vaccine-preventable disease. Children’s between 9 months and 12 years of age are mostly affected and presents with fever and maculopapularrash. Despite the national immunization program, measles virus infection is common in India. Objectives of the study are 1. To study the suspected cases of measles virus infection with high fever and characteristic rashes, among children. 2. To detect antibody levels against measles virus by ELISA IgM and IgG.

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Measles is a highly contagious vaccine-preventable disease caused by the Morbilivirus. Measles vaccine was introduced in India in 1985 as a part of Universal Immunization Programme (UIP) which was given at 9 completed months of age. As vaccine coverage has increased, there has been a marked reduction in measles incidence in the pediatric age group; but at the same time, the average age, at which measles infection occurs, has significantly increased.

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Measles is a recurrent health problem in both advanced and developed countries. The World Health Organization (WHO) recommends anti-measles immunoglobulin M (Ig M) as the standard method of detecting the virus; however, many areas still present the inability to perform a serology test of anti-measles IgM.

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(BQ) Continued part 1, part 2 of the document Clinical virology - Principles & practice (Sixth edition) has contents: Measles virus, rabies and other lyssavirus infections, human parvoviruses, human retroviruses, the human polyomaviruses, human immunodeficiency viruses, human prion diseases,... and other contents. Invite you to refer.

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Infections. During infancy, a number of viruses have been associated with the inception of the asthmatic phenotype. Respiratory syncytial virus (RSV) and parainfluenza virus produce a pattern of symptoms including bronchiolitis that parallel many features of childhood asthma53,54. A number of long-term prospective studies of children admitted to the hospital with documented RSV have shown that approximately 40% will continue to wheeze or have asthma into later childhood53.

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The result in table 2 showed that a total of 24,818 were vaccinated against six different disease (tuberculosis, Tetanus, cerebrospinal meningitis, poliomyelitis, measles and Diphtheria) with the vaccines against cerebrospinal meningitis (CSM) and measles being the most administered. The result in table 3 showed immunization coverage as assessed by the questionnaire method indicate that the total 65.

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Kuru was the first chronic degenerative disease of man shown to be a slow virus infection, with incubation periods measured in years and with a pro- gressive accumulative pathology always leading to death. This established that virus infections of man could, after long delay, produce chronic degenera- tive disease and disease with apparent heredofamilial patterns of occurrence, and with none of the inflammatory responses regularly associated with viral infections.

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Both measles and rubella are seen in unvaccinated young adults, and an atypical form of measles is seen in adults immunized with either killed measles vaccine or killed vaccine followed in time by live vaccine. In contrast to classic measles, the eruption of atypical measles begins on the palms, soles, wrists, and knuckles, and the lesions may become purpuric. The patient with atypical measles can have pulmonary involvement and be quite ill.

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