Mechanical wounding
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Wounds cause structural and functional discontinuity of an organ. Wound healing, therefore, seeks to re-establish the normal morphology and functionality through intertwined stages of hemostasis, inflammation, proliferation, and tissue remodelling. Ivermectin, a macrolide, has been used as an endectoparasiticide in human and veterinary medicine practice for decades.
12p vigandhi 23-02-2022 10 1 Download
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In this study, nanofiber structures were obtained with convenient polymers (PVA [polyvinyl alcohol] and PCL [poly º-caprolactone]) derived from the herbal extracts of olive leaves, fumitory, and terebinth plants. Optimum nanofiber structures were identified by measuring viscosity and conductivity values and performing morphological analysis, characterization, and mechanical tests of the prepared solutions. The potential use for wound healing at the most efficient level was determined as a result of antibacterial analysis of the structures obtained.
15p tudichquannguyet 29-11-2021 7 1 Download
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The study of the mechanisms controlling wound healing is an attractive area within the field of biology, with it having a potentially significant impact on the health sector given the current medical burden associated with healing in the elderly population.
21p viansan2711 30-07-2021 10 1 Download
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Osteomyelitis is the infection and inflammation of the bone. Inappropriate use of antibiotics and multidrug resistance has raised the morbidity and mortality rate in chronic osteomyelitis. This study aims to determine the bacterial profile and antimicrobial susceptibility patterns of chronic osteomyelitis with special mention to various resistant mechanisms. Samples from osteomyelitis cases were aerobically cultured and isolates from culture positives were identified by standard procedures. Antimicrobial susceptibility testing was done by Kirby Bauer disk diffusion method.
9p chauchaungayxua12 29-07-2021 13 2 Download
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Mechanical damage is an unavoidable threat to the growth and survival of plants. Although a wound to senescing (lower) leaves improves plant vitality, a wound to younger (upper) leaves often causes damage to or death of the whole plant. Source-sink models are often used to explain how plants respond to biotic or abiotic stresses.
14p vijichea2711 28-05-2021 6 1 Download
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Alterations of bioelectrical properties of cells and tissues are known to function as wide-ranging signals during development, regeneration and wound-healing in several species. The Drosophila follicle-cell epithelium provides an appropriate model system for studying the potential role of electrochemical signals, like intracellular pH (pHi ) and membrane potential (Vmem), during development.
17p viwyoming2711 16-12-2020 9 1 Download
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Electrospinning is now being widely used as a potential tool for tissue engineering to manufacturing tissue grafts, wound dressings, medical fabrics, and drug delivery systems. Regarding biomaterials, polyurethane (PU) and polycaprolactone (PCL) and their combination are prospective candidates for the fabrication of electrospun membranes used in tissue engineering due to their suitable biocompatibility, biodegradability, and mechanical properties. Thus, this study investigates how to manipulate the electrospinning process of PU/PCL to obtain nanofibers with desired features.
5p trinhthamhodang9 04-12-2020 15 1 Download
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Evolvulus nummularius, is ethnomedicinally used as a medicine for hysteria, to cure burns, cuts, wounds and scropion stings. This plant has antihelminthic activity, wound healing activity, poor sedative and anticonvulsant properties. In this study, the antibacterial activity of crude methanol extract of E. nummularius was studied against three gram negative multidrug resistant strains E. aerogenes, P. aeruginosa and K. pneumoniae. This plant extract showed both bacteriostatic and bactericidal activity against all these bacterial strains. The extract was most active against E. aerogenes.
8p nguaconbaynhay6 23-06-2020 8 1 Download
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Plants respond differently to mechanical wounding and herbivore attack, using distinct pathways for defense. The versatile sweet potato sporamin possesses multiple biological functions in response to stress.
21p viminato2711 22-05-2020 8 0 Download
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Mechanical wounding can cause morphological and developmental changes in plants, which may affect the responses to abiotic stresses. However, the mechano-stimulation triggered regulation network remains elusive.
13p vihashirama2711 21-05-2020 12 1 Download
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Although the wound response of plants has been extensively studied, little is known of the rapid occlusion of wounded cell itself. The laticifer in rubber tree is a specific type of tissue for natural rubber biosynthesis and storage.
13p viharuno2711 24-04-2020 10 1 Download
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Secondary metabolites play an important role in the plant defensive response. They are produced as a defence mechanism against biotic stress by providing plants with antimicrobial and antioxidant weapons. In higher plants, the majority of secondary metabolites accumulate as glycoconjugates.
17p viharuno2711 21-04-2020 13 2 Download
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R2R3-MYB transcription factors (TFs) play important roles in plant growth and development, and response to biotic and abiotic stresses. However, their regulatory mechanisms in wound-induced anthocyanin biosynthesis in woody plants are largely unknown.
14p viuchiha2711 21-04-2020 7 1 Download
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The mechanism of graft incompatibility is not yet fully understood and many reports focus on this problem in order to understand the mechanisms of graft development. Graft incompatibility is reported due to the Structural or Anatomical reasons, physiological and biochemical reasons, nutritional deficiency and presence of viruses at an early phase in response to grafting, as well as the consequences of these events on the future graft response.
16p quenchua4 16-04-2020 15 2 Download
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Increase in animal population has resulted in rise in animal bite cases and thus increase the potential for transmission of zoonotic diseases. That is why it is very important to consider some factors while considering the likelihood of disease transmission which includes species of animal, type of injury, severity of injury, vaccination status, interval between incident and treatment, and various attributes of the injured person (age, underlying health, etc.). It is also important to have knowledge about the natural oral flora of the animal.
17p cothumenhmong3 22-02-2020 12 0 Download
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Treatment of castration-resistant prostate cancer (CRPC) patients with androgen deprivation therapy puts prostate cancer in remission while treatment with already available drugs in market including abirater one help in controlling advanced prostate cancers for sometime though fail to respond, evolve resistance mechanisms, and undergo genetic deregulations later on with poor patient survival rate and no cure.
24p nguathienthan2 26-12-2019 16 1 Download
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Diabetic foot ulcer is a major complication of diabetes mellitus, and probably the major component of the diabetic foot. Wound healing is an innate mechanism of action that works reliably most of the time. The present study was carried out in Department of Microbiology, in a tertiary care hospital, over a period of one year from June 2016 – May 2017. 50 diabetic patients with foot ulcer attending the Surgery Out Patient Department were included in the study. These patients were diabetic or detected to be diabetic by blood glucose estimation at the time of their visit to the hospital.
5p quenchua2 16-12-2019 28 0 Download
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Acinetobacter baumannii has emerged as an extensively-drug-resistant pathogen implicated in healthcare associated infections (HCAIs) such as ventilator associated pneumonia, urinary tract infection, bacteremia, septicemia, secondary meningitis, wound infection etc. In the recent past carbapenems had been drugs of choice for serious infections with Acinetobacter baumannii, but carbapenem resistant strains are rapidly emerging. This study assesses the prevalence and mechanisms of resistance for Meropenem, Imipenem among Acinetobacter species isolated from a tertiary care center.
7p kequaidan2 13-12-2019 23 0 Download
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The electrospinning process is highlighted with the ability of fabricating fibers with diameters on the nanometer scale, small inter-fibrous pore size and high porosity, vast possibilities for functionalization with high surface area to volume or mass ratio, ease of use and instrument setup, and adaptability. It attracted a great deal of attention due to its unique properties. Different polymers have been successfully electrospun into ultrafine fibers using this technique including synthetic polymers such as polyurethane (PU).
6p nguathienthan1 24-11-2019 13 1 Download
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This review presents the past and current efforts with a brief description on the featured properties of hydrogel membranes fabricated from biopolymers and synthetic ones for wound dressing applications. Many endeavors have been exerted during past ten years for developing new artificial polymeric membranes, which fulfill the demanded conditions for the treatment of skin wounds. This review mainly focuses on representing specifications of ideal polymeric wound dressing membranes, such as crosslinked hydrogels compatible with wound dressing purposes.
17p kequaidan1 16-11-2019 16 2 Download