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Membrane channels
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In ebook "Caveolins and caveolae: Roles in signaling and disease mechanisms" caveolae are 50-100 nm flask-shaped invaginations of the plasma membrane that are primarily composed of cholesterol and sphingolipids. Using modern electron microscopy techniques, caveolae can be observed as omega-shaped invaginations of the plasma membrane, fully-invaginated caveolae, grape-like clusters of interconnected caveolae (caveosome), or as transcellular channels as a consequence of the fusion of individual caveolae.
199p
ladongphongthanh1008
22-04-2024
5
2
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Part 1 book "Neuroscience" includes content: Electrical signals of nerve cells; voltage dependent membrane permeability; channels and transporters; synaptic transmission; neurotransmitters and their receptors; molecular signaling within neurons; synaptic plasticity; the somatic sensory system - touch and proprioception; pain, vision - the eye; central visual pathways.
338p
muasambanhan03
02-01-2024
4
2
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Ebook "Potassium channels: Methods and protocols" provides readers with the latest techniques and approaches used to study K+ channels. There are a wide range of topics covered in the book, such as channel structure; K+ channels and their roles in physiology and disease; single-molecule FRET; proteins expression levels in vivo; real-time correlation of channel activity; gating; pharmacology; physiological functions; and channelopathies.
346p
lucchinguyen
28-12-2023
3
2
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Ebook "Structure and dynamics of confined polymers" provide insight on biological processes involving confinement and form a basis for new biotechnological applications using polymers. In his paper Edmund DiMarzio asks: What is so special about polymers? Why are polymers so prevalent in living things? The chemist says the reason is that a protein made of N amino acids can have any of 20 different kinds at each position along the chain, resulting in 20 N different polymers, and that the complexity of life lies in this variety.
393p
loivantrinh
29-10-2023
8
4
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Part 1 book "Biochemistry" includes content: Biochemistry - an evolving science, protein composition and structure, exploring proteins and proteomes, DNA, RNA and the flow of genetic information, exploring genes and genomes, exploring evolution and bioinformatics, hemoglobin - portrait of a protein in action, enzymes - basic concepts and kinetics, catalytic strategies, regulatory strategies, carbohydrates, lipids and cell membranes, membrane channels and pumps, signal transduction pathways.
455p
oursky07
24-10-2023
10
4
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Calcium channel blocker overdose is usually very fatal and challenging to manage. The patients are usually asymptomatic on admission, but deteriorate very rapidly. Currently, there is no specific antidote, and the treatment is supportive requiring high level of critical care, and may necessitate extracorporeal membrane oxygenation. The use of high-dose insulin is reported to help stabilize the blood pressure and wean off inotropes.
4p
viintuit
26-09-2023
2
0
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Part 1 book "Pellock’s pediatric epilepsy" includes content: Pathophysiology of seizures in the developing brain; ion channels, membranes, and molecules in epilepsy and neuronal excitability; mutations in epilepsy - a network and neurodevelopmental perspective; metabolic and pharmacologic consequences of seizures; neuropathologic substrates of epilepsy.... and other contents.
580p
oursky03
28-08-2023
2
1
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The thesis is structured as follows: In Chapter 1, the scientific literature is summarized within the scope of this study. Chapter 2 provides a comprehensive overview of the principles of the applied computational approaches in this study. Chapter 3 identifies the important residues of the LsIA/α7 nAChR complex that affect the interactions between the toxin and the membrane protein due to C-terminal carboxylation of LsIA. The effects of C-terminal modification of LsIA on interactions with α3β2 nAChR, involved in cardiovascular diseases, were also investigated in Chapter 4.
234p
runthenight04
02-02-2023
6
2
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(BQ) Ebook Microfluidic devices in nanotechnology applications: Part 2 presents the following content: Microchip and capillary electrophoresis using nanoparticles; pillars and pillar arrays integrated in microfluidic channels: fabrication methods and applications in molecular and cell biology; nanocatalysis in microreactor for fuels; microfluidic synthesis of iron oxide and oxyhydroxide nanoparticles; metal nanoparticle synthesis in microreactors.
221p
runordie7
30-08-2022
9
3
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Epinephrine is a first-line drug for cardiopulmonary resuscitation, but its efficacy in the treatment of bupivacaine-induced cardiac toxicity is still in question. We hypothesized that epinephrine can reverse cardiac inhibition of bupivacaine by modulating ion flows through the ventricular myocyte membrane channels of rats.
8p
viisaacnewton
25-04-2022
10
1
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A new ciliate species Colpodidium zelihayildizae n. sp., which was discovered in a dry irrigation channel in Van (Turkey), was investigated morphologically using standard live and silver impregnation methods, and its SSU rRNA gene phylogeny was provided.
10p
dolomite36
30-12-2021
11
0
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Bioelectric phenomena have been found to exert influence on various developmental and regenerative processes. Little is known about their possible functions and the cellular mechanisms by which they might act during Drosophila oogenesis.
13p
vimariana2711
22-12-2020
17
0
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During Drosophila oogenesis, the follicular epithelium differentiates into several morphologically distinct follicle-cell populations. Characteristic bioelectrical properties make this tissue a suitable model system for studying connections between electrochemical signals and the organisation of the cytoskeleton.
17p
viwyoming2711
16-12-2020
15
1
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Membrane androgen receptors (mAR) are functionally expressed in a variety of tumor-cells including the breast tumor-cell line MCF-7. They are specifically activated by testosterone albumin conjugates (TAC). The mAR sensitive signaling includes activation of Ras-related C3 botulinum toxin substrate 1 (Rac1) and reorganization of the actin filament network.
10p
vimoscow2711
29-08-2020
14
1
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Human triple-negative breast cancer has limited therapeutic choices. Breast tumor cells have depolarized plasma membrane potential. Using this unique electrical property, we aim to develop an effective selective killing of triple-negative breast cancer.
12p
vimale2711
21-08-2020
11
2
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Unlike other breast cancer subtypes that may be treated with a variety of hormonal or targeted therapies, there is a need to identify new, effective targets for triple-negative breast cancer (TNBC). It has recently been recognized that membrane potential is depolarized in breast cancer cells.
14p
vivientiane2711
30-06-2020
11
0
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The endoplasmic reticulum (ER) Ca2+ sensor, stromal interaction molecule1 (STIM1) activates the plasma membrane (PM) channel Orai1 in order to mediate store-operated Ca2+ entry (SOCE) in response to ER store depletion.
10p
vikuala271
13-06-2020
6
0
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Metabolite, ion and protein translocation into chloroplasts occurs across two membranes, the inner and the outer envelope. Solute and metabolite channels fulfill very important functions in integrating the organelles into the metabolic network of the cell.
10p
viminato2711
22-05-2020
14
1
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Arachidonic acid (AA 20:4n-6) is an essential component of cell membranes and modulates cell membrane fluidity. AA is metabolized by cyclo-oxygenase (COX), lipoxygenase (LOX) and cytochrome P450 enzymes to form several metabolites that have important biological actions. Of all the actions, role of AA in the regulation of blood pressure and its ability to prevent both type 1 and type 2 diabetes mellitus seems to be interesting.
13p
trinhthamhodang1
14-11-2019
19
3
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It is time to shift the arachidonic acid (ARA) paradigm from a harm-generating molecule to its status of polyunsaturated fatty acid essential for normal health. ARA is an integral constituent of biological cell membrane, conferring it with fluidity and flexibility, so necessary for the function of all cells, especially in nervous system, skeletal muscle, and immune system. Arachidonic acid is obtained from food or by desaturation and chain elongation of the plant-rich essential fatty acid, linoleic acid.
9p
trinhthamhodang1
14-11-2019
22
0
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