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Metabolic alterations
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Emerging evidence suggests that the gut microbiota is associated with various intracranial neoplastic diseases. It has been observed that alterations in the gut microbiota are present in gliomas, meningiomas, and pituitary neuroendocrine tumors (Pit-NETs).
12p
vishanshan
27-06-2024
4
1
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Clear cell renal cell carcinoma (ccRCC) is the prevailing histological subtype of renal cell carcinoma and has unique metabolic reprogramming during its occurrence and development. Cell senescence is one of the newly identified tumor characteristics. However, there is a dearth of methodical and all-encompassing investigations regarding the correlation between the broad-ranging alterations in metabolic processes associated with aging and ccRCC.
23p
vishanshan
27-06-2024
2
1
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Ebook "Mitochondria and cancer" presents thorough analyses of mitochondrial dysfunction as one of the hallmarks of cancer, discusses the clinical implications of mitochondrial defects in cancer, and as unique cellular targets for novel and selective anti-cancer therapy. These include differences in mitochondrial metabolic activity, molecular composition of mitochondria and mtDNA sequence, as well as in alteration of nuclear genes encoding mitochondrial proteins.
294p
ladongphongthanh1008
22-04-2024
4
1
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Part 2 book "Textbook of oral medicine, oral diagnosis and oral radiology" includes content: Dental caries, pulp and periapical lesions; gingival and periodontal diseases; regressive alterations of teeth; systemic disorders and their clinical implications; bone diseases and fibro osseous lesions; autoimmune disorders; granulomatous diseases; sexually transmitted diseases; nutritional and metabolic disorders;.... and other contents.
495p
muasambanhan10
06-04-2024
6
2
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Human pancreatic islets are a central focus of research in metabolic studies. Transcriptomics is frequently used to interrogate alterations in cultured human islet cells using single-cell RNA-sequencing (scRNAseq). We introduce single-nucleus RNA-sequencing (snRNA-seq) as an alternative approach for investigating transplanted human islets.
17p
vibransone
28-03-2024
4
2
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Dyslipidemia is a major risk factor for cardiovascular disease, and diabetes impacts the lipid metabolism through multiple pathways. In addition to the standard lipid measurements, apolipoprotein concentrations provide added awareness of the burden of circulating lipoproteins.
18p
viellison
28-03-2024
6
2
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Ebook "Metabolism in cancer" presents concise chapters written by internationally respected experts on various important aspects of cancer-associated metabolism, offering a comprehensive overview of the central features of this exciting research field.
272p
cotieubac1004
15-03-2024
2
0
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Interactions between the gut microbiota, diet, and host metabolism contribute to the development of cardiovascular disease, but a firm link between disease-specific gut microbiota alterations and circulating metabolites is lacking.
12p
vicwell
29-02-2024
9
1
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Ebook "Sphingolipids as signaling and regulatory molecules" attempts to analyze the latest discoveries in sphingolipid biology and how the alteration of their metabolism leads to altered signaling events and to the development of pathobiological disorders, such as cancer, cardiovascular diseases, asthma, diabetes, inflammation and infectious diseases.
311p
tachieuhoa
28-01-2024
6
2
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Part 2 book "Heart failure - A companion to Braunwald's heart disease" includes content: Alterations in cardiac metabolism, alterations in nutrition and body mass in heart failure, epidemiology of heart failure, heart failure as a consequence of ischemic heart disease, heart failure as a consequence of restrictive cardiomyopathy, the prognosis of heart failure,... and other contents.
322p
muasambanhan03
02-01-2024
3
2
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Ebook "Proteases and cancer: Methods and protocols" explores the role of proteases in various catalytic classes and cellular processes associated with cancer. The chapters in this book cover topics such as encoding proteolytic enzymes, cleavage sites of proteases, functional catalytic domains of MMPs, zymography, angiogenesis and lymphangiogenesis, genetic and epigenetic alterations of metallopeptidases, and methods to target metalloproteinases.
355p
lucchinguyen
28-12-2023
3
2
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Metabolic reprogramming is a hallmark of cancer, alteration of nucleotide metabolism of hepatocellular carcinoma (HCC) is not well-understood. MYBL2 regulates cell cycle progression and hepatocarcinogenesis, its role in metabolic regulation remains elusive.
13p
vileonardodavinci
23-12-2023
3
2
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The incidence of colorectal cancer (CRC) is considered to be the third-highest malignant tumor among all carcinomas. The alterations in cellular bioenergetics (metabolic reprogramming) are associated with several malignant phenotypes in CRC, such as tumor cell proliferation, invasion, metastasis, chemotherapy resistance, as well as promotes its immune escape.
12p
vialfrednobel
23-12-2023
5
3
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Breast cancer survivors face long-term sequelae compared to the general population, suggesting altered metabolic profiles after breast cancer. We used metabolomics approaches to investigate the metabolic differences between breast cancer patients and women in the general population, aiming to elaborate metabolic changes among breast cancer patients and identify potential targets for clinical interventions to mitigate long-term sequelae.
11p
vischultz
20-10-2023
1
1
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Breast cancer is associated with alterations in lipid metabolism. The treatment of breast cancer can also affect serum lipid composition. The purpose of this study was the examination of serum fatty acids (FAs) profiles in breast cancer survivors to assess if the FA levels normalize.
14p
visharma
20-10-2023
3
2
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Ovarian cancer (OC) is a highly lethal gynecological malignancy. Extensive research has shown that OC cells undergo signifcant metabolic alterations during tumorigenesis. In this study, we aim to leverage these metabolic changes as potential biomarkers for assessing ovarian cancer.
15p
vioracle
29-09-2023
7
2
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Part 3 book "Essentials of pathophysiology concepts of altered health states" includes content: Structure and function of the skeletal system; disorders of the skeletal system - trauma, infections, neoplasms, and childhood disorders; disorders of the skeletal system - metabolic and rheumatic disorders; structure and function of the integumentum; disorders of skin integrity and function.
672p
oursky04
05-09-2023
4
1
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Undernutrition is an increasingly common problem. Insufficient calorie intake and nutrient deficiencies during pregnancy may have an impact not only on the mother, but may also alter metabolism in the infant. In this study, we have applied a calorie-restricted diet during gestation and examined its effect on hepatic Fasn mRNA and DNA methylation profiles in rats and their female progeny.
8p
vinarcissa
21-03-2023
1
1
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Preeclampsia reduces placental expression and activity of 11β-hydroxysteroid dehydrogenase type 2 (HSD11B2), leading to an increase in fetal glucocordicoids. The latter has been proposed to be associated with low birth weight and high risk of metabolic diseases in later life of the offspring.
6p
vinarcissa
21-03-2023
2
1
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The most important types of abiotic stress that affect agricultural crops throughout the world are drought and salinity. These stresses will continue to worsen as the current climate crisis progresses. Plants have evolved a complex set of mechanisms in order to protect themselves from salt and drought. At the macrobiological level, these include alterations in growth rate, water balance, antioxidant defenses, and photosynthesis.
20p
lyhuyenthu
31-01-2023
6
2
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