![](images/graphics/blank.gif)
MicroRNA regulation
-
Epigenetic alterations contribute greatly to the development and progression of colorectal cancer, and effect of aberrant miR-622 expression is still controversial. This study aimed to discover miR-622 regulation in CRC proliferation.
12p
vishanshan
27-06-2024
1
1
Download
-
Circular RNA (circRNAs) have been found to play major roles in the progression of colorectal cancer (CRC). However, the functions of circ_0008345 (transcribed by PTK2) in regulating CRC development remain undefined. In this study, we aimed to explore the roles and underlying mechanisms of circ_0008345 in CRC.
13p
vikoch
27-06-2024
1
1
Download
-
Colorectal cancer (CRC) is a common malignancy worldwide. MicroRNAs (miRNAs) are important epigenetic alterations that notably impact various physiological and pathological processes by acting as negative regulators of gene expression. Furthermore, they have a vital function in different types of cancers, including CRC.
7p
vikoch
27-06-2024
1
1
Download
-
Ebook "Frontiers in computational and systems biology" consists of 19 chapters and covers a wide spectrum of topics. Described applications of an RNA structure sampling algorithm to the rational design of short interfering RNAs for gene silencing by RNA interference and to target identification for microRNAs that play important roles in posttranscriptional gene regulation.
411p
ladongphongthanh1008
22-04-2024
5
2
Download
-
Ebook "The long and short noncoding RNAs in cancer biology" conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance).
455p
tracanhphuonghoa1007
22-04-2024
4
2
Download
-
IL-4-driven alternative macrophage activation and proliferation are characteristic features of both antihelminthic immune responses and wound healing in contrast to classical macrophage activation, which primarily occurs during inflammatory responses.
22p
vioraclene
31-03-2024
4
2
Download
-
Abnormal DNA methylation is observed as an early event in breast carcinogenesis. However, how such alterations arise is still poorly understood. microRNAs (miRNAs) regulate gene expression at the posttranscriptional level and play key roles in various biological processes.
21p
vibransone
28-03-2024
4
2
Download
-
Ebook "Root genomics" examines how various new genomic technologies are rapidly being applied to the study of roots, including high-throughput sequencing and genotyping, TILLING, transcription factor analysis, comparative genomics, gene discovery and transcriptional profiling, post-transcriptional events regulating microRNAs, proteome profiling and the use of molecular markers such as SSRs, DArTs, and SNPs for QTL analyses and the identification of superior genes/alleles.
328p
tachieuhoa
28-01-2024
5
2
Download
-
Ebook "Bioinformatics in microRNA research" provides an in-depth introduction to and discussion of microRNAs (miRs) and their targets, miR functions, and computational techniques applied in miR research, thus serving the need for a comprehensive book focusing on miR target genes, miR regulation mechanisms, miR functions performed in various human diseases, and miR databases/knowledgebases.
283p
lucchinguyen
28-12-2023
7
3
Download
-
Ebook "MicroRNA protocols (Third edition)" focuses on the analysis of miRNA and its many components such as targets and expression profiling, regulation of gene expression, miRNA detection in biofluids, and its application in cancer and wound healing. The chapters in this book explore topics that’s cover biogenesis, isolation and profiling of miRNA, exosomal miRNAs, and the study of the functional significance of miRNAs.
314p
lucchinguyen
28-12-2023
5
2
Download
-
Cancer stem cells form a rare cell population in tumors that contributes to metastasis, recurrence and chemoresistance in cancer patients. Circular RNAs (circRNAs) are post-transcriptional regulators of gene expres‑ sion that sponge targeted microRNA (miRNAs) to affect a multitude of downstream cellular processes.
15p
vialfrednobel
23-12-2023
3
2
Download
-
MicroRNAs (miRNAs) are small non-coding RNAs that play a crucial role in regulating gene expression post-transcriptionally. These molecules have been implicated in various diseases, including cancer, viral infections, cardiovascular disorders, and neurodegenerative conditions. This study introduces a novel approach for predicting miRNA-disease associations by leveraging heterogeneous graph representation learning.
10p
visharma
20-10-2023
4
2
Download
-
MicroRNAs (miRNAs) have been reported to serve as potential biomarkers in bladder cancer and play important roles in cancer progression. This study aimed to investigate the biological role of miR-205-3p in bladder cancer. We showed that miR-205-3p was significantly down-regulated in bladder cancer tissues and cells.
13p
visharma
20-10-2023
2
2
Download
-
There is considerable evidence that microRNAs (miRNAs) regulate several key tumor-associated genes/ pathways and may themselves have a dual regulatory function either as tumor suppressors or oncogenic miRNA, depending on the tumor type.
13p
visharma
20-10-2023
4
2
Download
-
Part 1 book "Oocyte physiology and development in domestic animals" includes content: Regulation of oocyte meiotic resumption by somatic cells; oocyte development before and during folliculogenesi; the in vitro culture of ovarian follicles - a brief history and current considerations; oocyte secreted factors in domestic animals, MicroRNAs in oocyte physiology and development,.... and other contents.
129p
oursky06
17-10-2023
3
3
Download
-
Studies have shown that microRNA-191 (miR-191) is involved in the development and progression of a variety of tumors. However, the function and mechanism of miR-191 in oral squamous cell carcinoma (OSCC) have not been clarified.
15p
vioracle
29-09-2023
4
2
Download
-
Researchers have been exploring the molecular mechanisms underlying the control of periodontal ligament stem cell (PDLSC) osteogenic differentiation. Recently, long noncoding RNAs (lncRNAs) and circular RNAs (circRNAs) were shown to function as competitive endogenous RNAs (ceRNAs) to regulate the effect of microRNAs (miRNAs) on their target genes during cell differentiation.
13p
vinarcissa
21-03-2023
2
1
Download
-
MicroRNAs (miRNAs) are a novel class of endogenous, non-coding, single-stranded RNAs capable of regulating gene expression by suppressing translation or degrading mRNAs. Single nucleotide polymorphisms (SNP) can alter miRNA expression, resulting in diverse functional consequences.
10p
vinarcissa
21-03-2023
3
1
Download
-
The 3’ untranslated region (3’UTR) of mRNA is the binding target of microRNA and RNA binding proteins. Their interactions regulate mRNA level in specific subcellular regions and determine the intensity of gene repression. The mutations in the coding region of voltage-gated sodium channel alpha 1 subunit gene, SCN1A, were identified in epileptic patients and confirmed as causative factors of epilepsy.
12p
vinarcissa
21-03-2023
4
1
Download
-
Retinal function is ordered by interactions between transcriptional and posttranscriptional regulators at the molecular level. These regulators include transcription factors (TFs) and posttranscriptional factors such as microRNAs (miRs).
15p
vinarcissa
21-03-2023
4
1
Download
CHỦ ĐỀ BẠN MUỐN TÌM
![](images/graphics/blank.gif)