Mouse model of autism

The aims of the study "Characterising microbial and neuroimmune interactions in a mouse model of autism" are threefold: i) To characterize the influence of the R451C mutation on caecal enteric neuron organization; ii) To characterize the influence of the R451C mutation on caecal patch macrophage density and morphology; iii) To assess for alterations in gut microbes in different regions of the GI tract in the NL3R451C mouse model of autism.

83p runthenight04 02-02-2023 10 2   Download

"Master's thesis of Science: Intestinal permeability and functional properties of duodenal enteric neurons in a mouse model of autism" is structured as follows: Chapter 1: Introduction; Chapter 2: Measuring intestinal permeability in the Neuroligin-3R451C mouse model of autism; Chapter 3: Optimisation of the patch-clamp recording technique in the enteric nervous system to examine action potential characteristics in mouse duodenal myenteric neurons.

147p runthenight04 02-02-2023 11 4   Download