Neurologic function

Pediatric low-grade glioma (pLGG) is essentially a single pathway disease, with most tumors driven by genomic alterations affecting the mitogen-activated protein kinase/ERK (MAPK) pathway, predominantly KIAA1549::BRAF fusions and BRAF V600E mutations. This makes pLGG an ideal candidate for MAPK pathway-targeted treatments.

11p vikoch 27-06-2024 1 1   Download

Our understanding of neurological diseases has been tremendously enhanced over the past decade by the application of new technologies. Genome-wide association studies have highlighted glial cells as important players in diseases. Single-cell profiling technologies are providing descriptions of disease states of neurons and glia at unprecedented molecular resolution.

13p viellison 28-03-2024 5 1   Download

Part 3 book "Medical-Surgical nursing critical thinking for person centred care" includes contents: Responses to altered respiratory function, responses to altered musculoskeletal function, responses to altered neurological function, responses to altered visual and auditory function, responses to altered reproductive function, special topics in medical–surgical nursing

806p muasambanhan09 16-03-2024 1 0   Download

Ebook "The sticky synapse: Cell adhesion molecules and their role in synapse formation and maintenance" are responsible for the functional differences between the various types of neuronal synapses, have become one of the central themes of modern neurobiology. It is becoming increasingly clear that a misregulation of synaptogenesis and synaptic remodeling and dysfunctional neuronal synapses are at the heart of several human diseases, both neurological disorders and psychiatric conditions.

451p manmanthanhla0201 27-02-2024 3 1   Download

Part 1 book "Practical physiotherapy for small animal practice" includes content: Introduction; anatomy structure and function of the musculoskeletal system; healing; clinical examination; modalities; manual therapies; common neurological conditions and their rehabilitation.

155p muasambanhan06 03-02-2024 3 1   Download

Transverse myelitis is a rare neurological disorder of the spinal cord, caused by inflammation and damage of the myelin sheath of the neurons of the spinal cord across one or more spinal segments. This causes a disruption in the passage of nervous signals leading to motor, sensory, and autonomic dysfunction. This affects the physical and psychological health, as well as the functional status of the patient.

9p vitiki 30-01-2024 7 2   Download

Nitrous oxide is a medical and household gas that has seen its use drift to recreational purpose among the young population in recent years. Significant neurological, hematological and psychiatric side effects, generally related to an induced functional vitamin B12 deficiency, have been described separately in the literature.

7p vitiki 30-01-2024 5 2   Download

Part 2 book "Xie's veterinary acupuncture" includes content: Canine classical acupoints, general rules of acupuncture therapy, acupuncture for treatment of musculoskeletal and neurological disorders, acupuncture for internal medicine, acupuncture for acute and miscellaneous conditions, techniques of veterinary acupuncture and moxibustion, functional neuroanatomical physiology of acupuncture.

144p muasambanhan02 18-12-2023 2 0   Download

The integrated stress response (ISR) facilitates cellular adaptation to unfavorable conditions by reprogramming the cellular response. ISR activation was reported in neurological disorders and solid tumors; however, the function of ISR and its role as a possible therapeutic target in hematological malignancies still remain largely unexplored.

17p vileonardodavinci 23-12-2023 4 3   Download

Part 1 book "Practical guide to canine and feline neurology" includes content: Signalment and history - the first considerations, performing the neurologic examination, lesion localization - functional and dysfunctional neuroanatomy, differential diagnosis, neurodiagnostics, principles and application of magnetic resonance imaging, encephalopathies - disorders of the brain, head trauma management; seizures and narcolepsy; involuntary movements and paroxysmal disorders; disorders of hearing and balance - The vestibulocochlear nerve and associated structures.

312p muasambanhan02 18-12-2023 7 3   Download

Part 2 book "Anesthesiology" includes content: Perioperative information management systems, hemodynamic monitoring, intraoperative transesophageal echocardiography - a systematic approach, monitoring respiratory function, intraoperative neurologic monitoring, monitoring and managing neuromuscular blockade,.... and other contents.

844p oursky06 13-10-2023 7 2   Download

Acute flaccid myelitis (AFM) is a neurological disorder that affects the anterior horn of the spinal cord, resulting in progressive weakness, loss of motor function, hypotonia and hyporeflexia. Given the progressive and frequently long-term neurological involvement of AFM, patients may require anesthetic care during radiological imaging or other surgical procedures, such as a tracheostomy or the placement of a gastrostomy tube.

4p viintuit 26-09-2023 3 0   Download

Part 2 book "Pathophysiology - The biologic basis for disease in adults and children" includes content: Structure and function of the neurologic system, pain, temperature regulation, sleep, and sensory function alterations in cognitive systems, cerebral hemodynamics, and motor function, disorders of the central and peripheral nervous systems and the neuromuscular junction alterations of neurologic function in children,...and other contents.

2258p oursky03 28-08-2023 2 1   Download

There are few reports of trigger wrist in the literature, as it is a rare pathology. Furthermore, various authors report that it is also hard to diagnose. It manifests with neurological symptoms at the affected wrist, which are usually induced by wrist movement, and can lead to partial or full loss of wrist function and sensitivity.

4p vigamora 23-05-2023 5 2   Download

Non-coding single nucleotide polymorphisms within the nicotinic acetylcholine receptor alpha 4 subunit gene (CHRNA4) are robustly associated with various neurological and behavioral phenotypes including schizophrenia, cognition and smoking.

7p vinarcissa 21-03-2023 1 1   Download

Over 170 post-transcriptional RNA modifications have been described and are common in all kingdoms of life. These modifications range from methylation to complex chemical structures, with methylation being the most abundant. RNA modifications play a key role in RNA folding and function and their dysregulation in humans has been linked to several diseases such as cancer, metabolic diseases or neurological disorder

10p viginny 23-12-2022 13 3   Download

Tryptophan, an essential amino acid, and its metabolites are involved in many physiological processes including neuronal functions, immune system, and gut homeostasis. Alterations to tryptophan metabolism are associated with various pathologies such as neurologic, psychiatric disorders, inflammatory bowel diseases (IBD),

10p vironald 15-12-2022 8 2   Download

The benzodiazepine midazolam is a γ-aminobutyric acid (GABA)-A receptor agonist frequently used for sedation or stress control in patients suffering from traumatic brain injury (TBI). However, experimental studies on benzodiazepines have reported divergent results, raising concerns about its widespread use in patients. Some studies indicate that benzodiazepine-mediated potentiation of GABAergic neurotransmission is detrimental in brain-injured animals.

10p viisaacnewton 26-04-2022 5 1   Download

Hypothermia has been used in cardiac surgery for many years for neuroprotection. Mild hypothermia (MH) [body temperature (BT) kept at 32–35°C] has been shown to reduce both mortality and poor neurological outcome in patients after cardiopulmonary resuscitation (CPR). T

7p viisaacnewton 26-04-2022 10 1   Download

At present, sevoflurane inhalation anesthesia used on infants is well-known. But long-time exposure to inhalation anesthetic could cause neurologic disorder, especially nerve degeneration in infant and developing brain. The central nervous system degeneration of infants could affect the memory and cognitive function. γ-Aminobutyric acid (GABA) is a known inhibitory neurotransmitter in central nervous system.

8p viisaacnewton 26-04-2022 9 1   Download