Neutrophil extracellular traps

As circulating DNA (cirDNA) is mainly detected as mononucleosome-associated circulating DNA (mono-N cirDNA) in blood, apoptosis has until now been considered as the main source of cirDNA.

24p vicwell 29-02-2024 1 1   Download

There is little knowledge, whether in patients with sepsis neutrophil extracellular trap (NET) formation and NET degrading nuclease activity are altered. Thus, we tested the hypotheses that 1) NET formation from neutrophils of septic patients is increased compared to healthy volunteers, both without stimulation and following incubation with mitochondrial DNA (mtDNA), a damage-associated molecular pattern, or phorbol 12-myristate 13-acetate (PMA; positive control) and 2) that serum nuclease activities are increased as well.

9p vizhangzhidong 29-12-2021 10 0   Download

The hypercoagulable state associated with pancreatic adenocarcinoma (PDA) results in increased risk of venous thromboembolism, leading to substantial morbidity and mortality.

12p vibaku2711 22-07-2020 10 2   Download

(bq) part 2 book “inflammation fundamental mechanisms” has contents: leukocyte adhesion, neutrophil extracellular traps, sepsis, granulomatous inflammation, immune-related, idiopathic granulomatous inflammation.

186p dien_vi09 21-10-2018 16 1   Download