![](images/graphics/blank.gif)
NHC ligands
-
Ebook "Anti-cancer N-heterocyclic carbene complexes of Gold(III), Gold(I) and Platinum(II): Thiol “switch-on” fluorescent probes, thioredoxin reductase inhibitors and endoplasmic reticulum targeting agents" focuses on the development of gold- and non-classical platinum-based anti-cancer agents that display distinctively different anti-cancer mechanisms compared to the commonly used cisplatin.
175p
lamquandat
28-12-2023
10
3
Download
-
The new complexes (1–3) were characterized by elemental analysis and spectroscopic methods and the molecular structure of 1a was determined by X-ray diffraction studies. These complexes were applied in the Suzuki–Miyaura cross-coupling reaction of phenylboronic acid with aryl halides in neat water. The activities of catalysts were monitored by gas chromatography–flame ionization detector and nuclear magnetic resonance.
10p
langthannam
29-12-2021
12
0
Download
-
NHC–Pd(II) complexes bearing a chiral oxazoline ligand (IIIa–f) were synthesized by cleavage of dimeric palladium complexes with the oxazoline ligand. They were fully characterized by 1 H and 13 C NMR and elemental analyses. The catalytic activity of the complexes (IIIa–f) in allylic alkylation reactions was evaluated. The complex IIIa was found to be the most active catalyst. Very low ee values indicate that the oxazoline is dissociated from the active catalytic species.
7p
langthannam
29-12-2021
7
0
Download
-
In this account the authors’ latest results in C–C coupling catalysis are reviewed. First, an efficient catalytic system for the Kumada–Tamao–Corriu coupling reaction based on NHC-phosphine (NHC = N-heterocyclic carbene) nickel complexes is presented. Then the use of palladium complexes of chiral ferrocenyl NHC-phosphines in the asymmetric Suzuki–Miyaura coupling reaction is reported. High catalytic activities and moderate enantioselectivities (ee up to 46%) were obtained.
13p
langthannam
29-12-2021
9
0
Download
-
Two N -heterocyclic carbene (NHC) palladium complexes of formula [PdBr2(NHC)(pyridine)] in which the carbenic ring is flanked by sterically crowded cavitand substituents were prepared from appropriate imidazolium salts bearing either two resorcinarene or a combination of resorcinarene and calixarene fragments. Both complexes displayed high stability and good activities in the cross-coupling of aryl bromides with phenyl boronic acid. One of the imidazolium salts was characterised by an X-ray diffraction study.
9p
langthannam
29-12-2021
6
0
Download
-
Resorcinarene-mono-benzimidazolium salts as NHC ligands for Suzuki–Miyaura cross-couplings catalysts
Two mono-benzimidazolium salts of resorcinarene have been prepared and used as ligands in Suzuki–Miyaura cross-coupling reactions. They have been fully characterized by 1H and 13C NMR, MALDI, and FT-IR spectroscopic methods, and their structures were confirmed by X-ray diffraction analysis. These two new resorcinarene-based monobenzimidazolium salts showed good catalytic activity for coupling reactions in DMF. The highest conversion was achieved for arylation of 4-bromotoluene using the resorcinarenyl mono-dimethylbenzimidazolium salt.
11p
langthannam
29-12-2021
9
0
Download
-
Novel five-membered (κ2−C,N) -palladacyclic complexes were prepared from the reaction of the corresponding acetate-bridged palladacycle dimer with N-heterocyclic carbene (NHC) ligands in high yields. Palladacyclic complexes (3) were fully characterized by elemental analysis and 1H and 13C NMR spectroscopy. Palladacyclic complexes were tested as catalyst for the C–C bond forming reaction. These complexes were found to be efficient catalysts for the Suzuki–Miyaura reaction of aryl bromides.
7p
langthannam
29-12-2021
15
0
Download
-
The novel ruthenium(II) complexes [RuCl2(NHC)(p-cymene)], 3a–e, containing 1-alkyl-3-benzylimidazol2-ylidene ligands were prepared. All synthesized compounds were characterized by NMR spectroscopy and elemental analyses. Ru(II)-NHC complexes were tested as catalysts for the transfer hydrogenation of acetophenone, showing modest to high activity in this reaction. The results revealed that efficiencies depend on the substituents of the benzene ring of the benzyl on the N atom of the NHC ring.
9p
langthannam
29-12-2021
10
0
Download
-
The compounds were characterized by spectroscopic and elemental analyses. The synthesized NHC–Ag(I) complexes (3a–c) were tested as catalysts for the catalytic threecomponent coupling reaction of aldehyde, alkyne, and amine to propargylamines in various solvents. All complexes were active catalysts for catalytic three-component coupling reactions with good yields under neat and mild conditions (after 4 h, yields of up to 94%).
7p
langthannam
29-12-2021
6
0
Download
-
New furanoside-based NHC precursor salts (2) were synthesized using amino alcohols from the chloralose derivatives of glucose (a), galactose (b), and mannose (c). The novel compounds were fully characterized by 1H NMR, 13C NMR, and elemental analyses. The catalytic activities of these salts were tested in the arylation of aldehydes as catalysts that were generated in situ from [RhCl(COD)]2. In addition, 2a was converted to the rhodium complex 3a in order to compare the results obtained in situ.
9p
langthannam
29-12-2021
4
0
Download
CHỦ ĐỀ BẠN MUỐN TÌM
![](images/graphics/blank.gif)