Non-parametric statistical analyse

Table 62-8 Genetic Approaches for Identifying Disease Genes Method Indications Advantages and Limitations Linkage Studies Classical linkage analysis Analysis of Difficult to collect (parametric monogenic traits large informative pedigrees methods) Suitable for genome scan Difficult to obtain sufficient statistical power for complex traits Control not required population Useful for multifactorial disorders in isolated populations Allele-sharing Suitable for Difficult to collect methods (nonparametric identification methods) susceptibility genes of sufficient nu...

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