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Oral growth
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Acromegaly can be diagnosed by a growth hormone value≥1 µg/L following an oral glucose tolerance test. However, normal growth hormone suppression following oral glucose tolerance test may not exclude acromegaly.
6p
vitiki
30-01-2024
4
2
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Aberrant fibroblast growth factor receptor (FGFR) signaling can substantially influence oncogenicity. Despite that FGFR gene abnormality is often detected by cancer genome profiling tests, there is no tumor-agnostic approval yet for these aberrations. E7090 (tasurgratinib) is an orally available selective tyrosine kinase inhibitor of FGFR1-3.
7p
vialfrednobel
23-12-2023
4
3
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Part 2 book "Handbook of laboratory animal science (Vol 2)" includes content: Animal models of lung physiology during anesthesia; animal models of female reproduction and fetal growth and development; animal models in vaccinology; animal models in aids research; animal models for the study of helicobacter infection; animal models in mycology; animal models in biodefense research; animal models in oral health sciences; animal models of hearing loss and tinnitus.
249p
oursky10
07-12-2023
3
3
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Studies have shown that microRNA-191 (miR-191) is involved in the development and progression of a variety of tumors. However, the function and mechanism of miR-191 in oral squamous cell carcinoma (OSCC) have not been clarified.
15p
vioracle
29-09-2023
4
2
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3D culture is increasingly used in cancer research, as it allows the growth of cells in an environment that mimics in vivo conditions. Metastases are the primary cause of morbidity and mortality in cancer patients, and solid tumour metastases are mostly located in lymph nodes.
12p
vioracle
29-09-2023
3
2
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Retinoblastoma is an intraocular cancer of infancy and childhood, which has been treated with radia‑ tion therapy and chemotherapy. Radiation on growing patients can cause deterioration in maxillofacial growth and development that leads to severe skeletal discrepancies between the maxilla and mandible, and dental problems such as crossbite, openbite, and hypodontia.
9p
videadpool
05-05-2023
3
2
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The epidermal growth factor receptors participate in the physiological processes such as regulation of morphogenesis, proliferation and cell migration, but when overexpressed or overactivated they may play an important role in neoplastic progression.
11p
vigalileogalilei
28-02-2022
9
1
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The prognosis of oral squamous cell carcinoma (OSCC) patients is difficult to predict or describe due to its high-level heterogeneity and complex aetiologic factors. Ferroptosis is a novel form of iron-dependent cell death that is closely related to tumour growth and progression. This study aims to clarify the predictive value of ferroptosis-related genes (FRGs) on the overall survival(OS) of OSCC patients.
16p
vimahuateng
26-11-2021
16
1
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Streptococcus salivarius is an abundant isolate of the human oral microbiota. Since both pH and glucose availability fluctuate frequently in the oral cavity, the goal of this study was to investigate regulation by CodY, a conserved pleiotropic regulator of Gram positive bacteria, in response to these two signals. The chemostat culture system was employed to precisely control the growth parameters, and the transcriptomes of wild-type S. salivarius 57.I and its CodY-null derivative (ΔcodY) grown at pH 7 and 5.5, with limited and excessive glucose supply were determined.
16p
vibeauty
23-10-2021
6
1
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School age period is a critical period of growth and development. In this period the activities, diet and nutrition of children influence their physical and cognitive development. The present study aimed to assess the nutritional status of school going children of 7-9 years old children on the basis of their food habits. The study was conducted among the government primary schools of rural areas of Kanpur Dehat, Uttar Pradesh. The data was collected by the pre-design oral questionnaires.
9p
chauchaungayxua12
29-07-2021
8
1
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Glutamine (Gln) supplementation during concurrent chemoradiotherapy (C-CRT) effectively reduces the incidence and severity of acute radiation-induced esophagitis (RIE). However, there are concerns that Gln might stimulate tumor growth, and therefore negatively impact the outcomes of anticancer treatment.
10p
viirene2711
03-10-2020
87
1
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Oral diseases are among the major public health problems and the most common of chronic diseases that affect mankind. Essential oils could serve as an important natural alternative to prevent microbial growth in oral infection diseases. This study was undertaken to determine the in vitro anticariogenic activities of 11 essential oils against dental pathogenic bacteria (Staphylococcus aureus, Streptococcus mutans and Streptococcus pyogenes) and fungi (Candida albicans and Candida parapsilosis) using agar well diffusion method, followed by determination of MIC.
14p
trinhthamhodang1215
23-09-2020
11
1
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Cancer cells may undergo metabolic adaptations that support their growth as well as drug resistance properties. The purpose of this study is to test if oral cancer cells can overcome the metabolic defects introduced by using small interfering RNA (siRNA) to knock down their expression of important metabolic enzymes.
10p
virose2711
25-09-2020
13
0
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Oral squamous cell carcinoma is an aggressive neoplasm with serious morbidity and mortality, which typically spreads through local invasive growth. Lysophosphatidic acid (LPA) is involved in a number of biological processes, and may have a role in cancer cell migration and invasiveness. LPA is present in most tissues and can activate cells through six different LPA receptors (LPAR1-6).
16p
virose2711
22-09-2020
12
2
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Axitinib is an orally active and potent tyrosine kinase inhibitor of vascular endothelial growth factor receptors 1, 2 and 3. This phase II study assessed the efficacy and safety of axitinib combined with cisplatin/gemcitabine in chemotherapy-naïve patients with advanced/metastatic (stage IIIB/IV) squamous non–small-cell lung cancer (NSCLC).
10p
vialabama2711
21-09-2020
7
0
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Tumor-associated macrophages (TAMs) are implicated in the growth, invasion and metastasis of various solid tumors. However, the phenotype of TAMs in premalignant lesions of solid tumors has not been clarified.
11p
viamsterdam
18-09-2020
11
0
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The Streptococci are Gram-positive spherical bacteria (cocci) that characteristically form pairs and chains during growth. They are widely distributed in nature. Some are members of the normal human flora for e.g. commensal Streptococci of the oral cavity, are common causes of sub-acute bacterial endocarditis, others are associated with important human disease attributable in part to injection by Streptococci, in part to sensitization to them. Streptococcus species is uniformly susceptible to penicillin. But macrolides remains drug of choice for patient allergic to penicillin.
13p
trinhthamhodang7
31-08-2020
8
2
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Eliminating cancer stem cells (CSCs) has been suggested for prevention of tumor recurrence and metastasis. Honokiol, an active compound of Magnolia officinalis, had been proposed to be a potential candidate drug for cancer treatment. We explored its effects on the elimination of oral CSCs both in vitro and in vivo.
13p
vinaypyidaw2711
26-08-2020
11
2
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Sorafenib is an orally active multikinase tyrosine kinase inhibitor (TKI) that targets B-type Raf kinase (BRAF), vascular endothelial growth factor receptors (VEGFR) 1 and 2, and rearranged during transfection (RET), inducing anti-angiogenic and pro-apoptotic actions in a wide range of solid tumors.
6p
vinaypyidaw2711
26-08-2020
14
2
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Iron is essential for cell replication, metabolism and growth. Because neoplastic cells have high iron requirements due to their rapid proliferation, iron depletion may be a novel therapeutic strategy for cancer. Deferasirox (DFX), a novel oral iron chelator, has been successful in clinical trials in iron-overload patients and has been expected to become an anticancer agent.
11p
vimale2711
25-08-2020
20
2
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