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Patterns of associations
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Part 2 of ebook "Principles of data mining (Third edition)" provides readers with contents including: Chapter 17 - Association rule mining II; Chapter 18 - Association rule mining III, frequent pattern trees; Chapter 19 - Clustering; Chapter 20 - Text mining; Chapter 21 - Classifying streaming data; Chapter 22 - Classifying streaming data II, time-dependent data;...
267p
daonhiennhien
03-07-2024
1
1
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Glioblastoma is a malignant and aggressive type of central nevous system malignancy characterized by many distinct biological features including extensive hypoxia. Hypoxia in glioblatoma associates with complex signaling patterns including activation of several pathways such as MAPK, PI3K-AKT/mTOR and IL-6/JAK/STAT3 with the master regulator HIF-1, which in turn drive particular tumor behaviors determining, in the end, treatment outcomes and patients fate.
12p
vishanshan
27-06-2024
2
1
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Bone tumors account for approximately 6% of all cancers in children. Malignant bone tumors, commonly occurring in children and adolescents, are associated with high mortality and morbidity. The overall survival of children with primary malignant bone tumors is affected by the stage of disease, time of diagnosis, and treatment response.
10p
vishanshan
27-06-2024
1
1
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Continued smoking after a cancer diagnosis can be associated with lower treatment tolerance, poorer outcomes, and reduced quality of life compared to non-smoking cancer patients or to those who have quit. Yet about 60% of patients continue to smoke after being diagnosed and find it difficult to quit.
14p
vishanshan
27-06-2024
2
1
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Breast cancer is a common cause for central nervous system (CNS) metastasis, resulting in a significant reduction in overall survival. Germline pathogenic variants (PVs) in BRCA1/2 are the most common genetic risk factor for breast cancer, associated with poor prognostic factors. This study sought to explore the patterns and outcome of CNS metastases in breast cancer patients with germline PVs in BRCA1/2 genes.
12p
vikoch
27-06-2024
1
1
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Childhood cancer survivors (CCS) are subject to a substantial burden of treatment-related morbidity. Engaging in health protective behaviors and eliminating risk behaviors are critical to preventing chronic diseases and premature deaths. This study is aimed to provide updated information on currently smoking, physical inactivity, binge drinking patterns and associated factors among CCS using a nationwide dataset.
18p
vikoch
27-06-2024
3
1
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Hypertension is prevalent in the elderly, affecting two-thirds of individuals aged 60 years and older. Ambulatory blood pressure measurement (ABPM) is recommended for diagnosing and managing hypertension in this population. This study aimed to characterize 24-hour ABPM profiles and their association with cardiovascular risk factors in older adults with high-risk hypertension.
10p
viambani
21-05-2024
3
2
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In the case of length weight relationship (LWR), the coefficient of determination value (r2 ) was found 0.96 and the slope was found b = 1.50 which indicated the pattern of negative allometric growth of this species as b < 3. In contrast, an increase was recorded in the fecundity associated with the rise of total length, body weight and gonad weight showed a significant linear relationship. This study would assist in the development of induced breeding techniques and provide valuable information for the sustainable management of this population in the inland open ecosystem.
11p
dianmotminh02
03-05-2024
3
1
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Spatial association and species diversity of species-rich tropical forests can be characterized by their spatial patterns. We applied the quantitative analyses based on relationships of spatial distribution of tree species. In a 2-ha plot of a tropical broadleaved forest stand in Kon Ha Nung, Gia Lai province, all tree individuals with DBH ≥ 2.5 cm were mapped and their characteristics (i.e., DBH and species) were recorded.
9p
vilarry
01-04-2024
8
0
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Exosomes are promising tools for improving cancer care, but conversely may also contribute to tumor progression. Here, we highlight recently discovered roles of exosomes in modulating immune responses in cancer, with emphasis on exosomal surface proteins and on RNA and DNA content. We also discuss how exosomes could be exploited as biomarkers and delivery vehicles in cancer therapy.
4p
vibransone
28-03-2024
2
2
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The expression of antigens that are recognized by self-reactive T cells is essential for immune-mediated tumor rejection by immune checkpoint blockade (ICB) therapy. Growing evidence suggests that mutation-associated neoantigens drive ICB responses in tumors with high mutational burden.
10p
vibransone
28-03-2024
6
2
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The aim of the study "Supply chain operational capability and supply chain operational performance: Does the supply chain management and supply chain integration matters?" is to recognize the pattern of the interactive association between SC operational capability and corporate competitive capability for improving performance. Moreover, the study is based on analyzing the influence of SC integration on the interactive relation as a strategic lever.
8p
longtimenosee07
29-03-2024
3
2
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Patterns in expression data conserved across multiple independent disease studies are likely to represent important molecular events underlying the disease. We present the INSPIRE method to infer modules of co-expressed genes and the dependencies among the modules from multiple expression datasets that may contain different sets of genes.
31p
vioraclene
31-03-2024
4
2
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Allele-specific expression (ASE) is differential expression of each of the two chromosomal alleles of an autosomal gene. We assessed ASE patterns in the human left atrium (LA, n = 62) and paired samples from the left ventricle (LV, n = 76) before and after ischemia, and tested the utility of differential ASE to identify genes associated with postoperative atrial fibrillation (poAF) and myocardial ischemia.
11p
vioraclene
31-03-2024
3
2
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DNA methylation has been shown to be associated with adiposity in adulthood. However, whether similar DNA methylation patterns are associated with childhood and adolescent body mass index (BMI) is largely unknown. More insight into this relationship at younger ages may have implications for future prevention of obesity and its related traits.
15p
vibransone
28-03-2024
8
2
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Epigenetic alterations are associated with normal biological processes such as aging or differentiation. Changes in global epigenetic signatures, together with genetic alterations, are driving events in several diseases including cancer. Comparative studies of cancer and healthy tissues found alterations in patterns of DNA methylation, histone posttranslational modifications, and changes in chromatin accessibility.
12p
vibransone
28-03-2024
7
2
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Most two-group statistical tests find broad patterns such as overall shifts in mean, median, or variance. These tests may not have enough power to detect effects in a small subset of samples, e.g., a drug that works well only on a few patients.
19p
vibransone
28-03-2024
4
1
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Recent studies have suggested that individual variants do not sufficiently explain the variable expressivity of phenotypes observed in complex disorders. For example, the 16p12.1 deletion is associated with developmental delay and neuropsychiatric features in affected individuals, but is inherited in > 90% of cases from a mildly-affected parent.
21p
vibransone
28-03-2024
8
2
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The association between microbes and cancer has been reported repeatedly; however, it is not clear if molecular tumour properties are connected to specific microbial colonisation patterns. This is due mainly to the current technical and analytical strategy limitations to characterise tumour-associated bacteria.
19p
vicwell
29-02-2024
4
1
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Normal cell BRCA1 epimutations have been associated with increased risk of triple-negative breast cancer (TNBC). However, the fraction of TNBCs that may have BRCA1 epimutations as their underlying cause is unknown. Neither are the time of occurrence and the potential inheritance patterns of BRCA1 epimutations established.
15p
vicwell
29-02-2024
6
1
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