Pharmacokinetic-pharmacodynamic
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: In adolescents limited data are available on the pharmacokinetics (PK) and pharmacodynamics (PD) of propofol. In this study we derived a PK-PD model for propofol in adolescents undergoing idiopathic scoliosis surgery with an intraoperative wake-up test with reinduction of anesthesia using both Bispectral Index (BIS) and composite A-line ARX index (cAAI) as endpoints.
12p vampires36 30-12-2021 12 0 Download
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Mitiglinide is a widely used agent for diabetic treatment. We established a pharmacokineticpharmacodynamic (PK-PD) model to illustrate the relationship between mitiglinide plasma concentration and its glucose lowering effects in healthy volunteers.
8p vimax2711 30-03-2020 8 1 Download