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Phosphatase activity
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Tumor-induced osteomalacia is a rare, acquired paraneoplastic syndrome, including hypophosphatemia, high serum alkaline phosphatase, reduced active vitamin D, suboptimal bone mineral density, bone pain, fragility fractures, and muscle weakness.
5p
vilazada
31-01-2024
5
2
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Part 1 book "Encyclopedia of immunobiology (Vol 3 - Activation of the immune system)" includes content: Adapter molecules in immune receptor signaling, immunological synapses, kinase and phosphatase effector pathways in T Cells, cellular metabolism controls lymphocyte activation and differentiation, signal Transduction by the B Cell antigen receptor,...and other contents.
308p
oursky06
17-10-2023
5
3
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CANT1, as calcium-activated protein nucleotidase 1, is a kind of phosphatase. It is overexpressed in some tumors and related to poor prognosis, but few studies explore its function and carcinogenic mechanism in hepatocellular carcinoma (HCC).
13p
visharma
20-10-2023
3
3
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Psoriasis is a chronic autoimmune disease characterized by abnormal proliferation and differentiation of keratinocytes and infiltration of inflammatory cells into the site of inflammation.
7p
vimulcahy
18-09-2023
4
3
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SEM and TEM were used to evaluate the surface morphology and microstructure of the fiber membrane. Ultraviolet spectrophotometry was used to detect drug release. A LIVE/DEAD Viability/Cytotoxicity Kit and fluorescence staining were used to detect cell morphology and activity. Alkaline phosphatase and calcium mineralization deposition were used to evaluate the osteoinductive activity of the scaffold. Dynamic mechanical analysis was used to determine the Young’s modulus, maximum load, and maximum elongation of the prepared scaffold.
12p
lyhuyenthu
31-01-2023
6
2
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Mesenchymal stem cells (MSCs) are undiferentiated cells that can give rise to a mesoderm lineage. Adipose-derived MSCs are an easy and accessible source for MSCs isolation, although each source of MSC has its own advantages and disadvantages. Our study identifies a promising source for the isolation and differentiation of canines MSCs.
12p
vidarwin
22-02-2022
15
1
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Prevascularization and mechanical stimulation have been reported as effective methods for the construction of functional bone tissue. However, their combined effects on osteogenic differentiation and its mechanism remain to be explored. Here, the effects of fluid shear stress (FSS) on osteogenic differentiation of rat bone-marrow-derived mesenchymal stem cells (BMSCs) when cocultured with human umbilical vein endothelial cells (HUVECs) were investigated, and underlying signaling mechanisms were further explored.
15p
langthannam
29-12-2021
9
0
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The main aim of the current study is to determine sufficient RANKL/MCSF concentrations for differentiation of the cells to osteoclasts and to describe the repressive effect of MEL on the osteoclastogenesis of these cells. In this regard, it was found that 10 ng/mL of RANKL- and MCSF-containing medium is suitable for inducing osteoclastogenesis of the cells. In addition, melatonin at doses in the range of 100–1000 µM does not have a cytotoxic effect.
10p
thiencuuchu
27-11-2021
7
2
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RNA polymerase II plays critical roles in transcription in eukaryotic organisms. C-terminal Domain Phosphatase-like 1 (CPL1) regulates the phosphorylation state of the C-terminal domain of RNA polymerase II subunit B1, which is critical in determining RNA polymerase II activity.
9p
vitzuyu2711
29-09-2021
7
1
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The above considerations in view, the present study was conducted to assess the impacts of different management schedules of pesticides on dehydrogenase, urease and phosphatase enzymes activity in a red soil of northern transition zone of Karnataka under cabbage cropping.
13p
trinhthamhodang11
27-04-2021
12
1
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An Investigation was carried out on enzymes activity during composting of urban waste with microbial consortium and activators (cow dung slurry, diary spent wash, biodigester liquid and bovine urine). Significant variation in dehydrogenase, phosphatase and urease activity was noticed among the treatments at all the intervals during composting of urban waste with activators. Dehydrogenase activity was increased at 30th day of composting and decreased at 60th day thereafter, it gradually increased at 120th day of composting.
8p
trinhthamhodang11
27-04-2021
12
1
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The experiment was done during kharif season 2016 at farmer field in Bhadohi district near Varanasi to ascertain the validity of developed fertilizer adjustment equations based on Soil Test Crop Response for targeted yield of this crop. These equations were compared with other fertilizer use practices such as farmer’s practice and general recommendation. Fertilizer doses for different crop under STCR based fertilizers application treatment were calculated using fertilizer adjustment equations for targeted yield of different crops. The percent increase in yield ware 17.11 and 37.
9p
trinhthamhodang1218
26-02-2021
18
3
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A field study was conducted during Kharif 2016 at the research farm of ICAR Complex for NEH Region (Umiam) Barapani, Meghalaya to find out the effect of different nutrient management practices and microbial inoculants on microbial properties in soil of lowland rice in Eastern Himalayas.
5p
cothumenhmong9
04-01-2021
13
2
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Physico- chemical properties of soil have profound influence on soil enzyme acid phosphatases activity. To study the distribution of soil enzyme acid phosphatase and influence of physico- chemical properties on soil enzyme acid phosphatases activity forty soil samples were collected from different villages of Ranga Reddy district of Telangana state. These samples were analysed for the physicochemical properties like pH, EC, available nutrients, texture and organic carbon and soil enzyme activity was assayed.
8p
cothumenhmong9
04-01-2021
14
2
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This review aims to strengthen the state of knowledge of different soil enzymes responsible for transformation of carbon (βglucosidase, xylanase and cellulase), nitrogen (urease and amidohydrolases), phosphorus (phosphatases and phytase) and organic matter decomposition in soil (dehydrogenase, fluorescein diacetate, phenol oxidase and peroxidase).
8p
gaocaolon9
22-12-2020
11
1
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Soil microorganisms are supportive in the transformation of soil phosphorus (P) and are thus an important component of the soil P cycle. These are effective in releasing P both from inorganic and organic pools of total soil P through their respective solubilizing and also enhance the soil microbial and enzymatic activities.
7p
trinhthamhodang1215
23-09-2020
17
1
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The phosphatase and tensin homolog deleted on chromosome 10 (PTEN) tumor suppressor protein is a central negative regulator of the PI3K/AKT signaling cascade and suppresses cell survival as well as cell proliferation.
9p
vijennie2711
29-09-2020
8
0
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PTEN inactivation is the most frequent genetic aberration in endometrial cancer. One of the phosphatase-independent roles of PTEN is associated with homologous recombination (HR) in nucleus. Poly (ADP-ribose) polymerase (PARP) plays key roles in the repair of DNA single-strand breaks, and a PARP inhibitor induces synthetic lethality in cancer cells with HR deficiency.
10p
virose2711
25-09-2020
16
0
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Tumor-associated macrophages (TAMs) are known to promote cancer progression and metastasis through the release of a variety of cytokines. Phosphatase of regenerating liver (PRL-3) has been considered as a marker of colorectal cancer (CRC) liver metastasis.
13p
virose2711
24-09-2020
9
0
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MicroRNAs (miRNAs) are frequently dysregulated in human cancers and can act as either potent oncogenes or tumor suppressor genes. In the present study, we intend to prove that the gene PTEN (phosphatase and tensin homolog deleted on chromosome ten) is a target gene of miR-205 and to investigate the suppressive effects on PTEN transcriptional activity by enhancing miR-205 expression in endometrial cancer Ishikawa cells.
8p
virose2711
22-09-2020
13
1
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