Primary disease
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Knowledge, attitude, and practice of hand-washing with soap among students at 4 primary schools in Hanoi in 2022. Research subjects and methods: A cross-sectional descriptive study was conducted at Khuong Thuong Primary School, Tam Khuong Primary School, Ha Hoi Primary School, and Khanh Ha Primary School, choosing 50 fourth graders and 50 fifth graders.
5p viwalton 02-07-2024 3 1 Download
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Pleuropulmonary blastoma (PPB) is a rare malignant tumor in childhood cancer. This type of tumor is difficult to identify and can easily be misdiagnosed. The International PPB protocol is a complicated and aggressive protocol
10p viwalton 29-06-2024 2 1 Download
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Primary central nervous system lymphoma (PCNSL) are rare mature B-cell lymphoproliferative diseases characterized by a high incidence of MYD88 L265P and CD79B Y196 hotspot mutations. The aim of the study was to analyze the detection rate of the MYD88 L265P and CD79B Y196 mutation in cell free DNA (cfDNA) in plasma of patients with PCNSL.
6p vishanshan 27-06-2024 1 1 Download
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The late presentation and diagnosis of OSCC account for the large number of patients with the advanced form of the disease. In The present study aims to investigate the survival of oral squamous cell carcinoma patients with a wide field of cancerization.
10p vishanshan 27-06-2024 2 1 Download
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Bone tumors account for approximately 6% of all cancers in children. Malignant bone tumors, commonly occurring in children and adolescents, are associated with high mortality and morbidity. The overall survival of children with primary malignant bone tumors is affected by the stage of disease, time of diagnosis, and treatment response.
10p vishanshan 27-06-2024 1 1 Download
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Government-led, population-wide initiatives are crucial for advancing the management of hypertension−a leading cause of cardiovascular disease (CVD) morbidity and mortality. An urban population health initiative was conducted against this backdrop, focussing on hypertension in the primary health system in São Paulo, Brazil. Within the frame of the initiative and under the supervision and leadership of the municipal health authorities, a situational analysis was conducted on the needs in hypertension management, marking the first phase of a Design Thinking process.
12p vishanshan 27-06-2024 2 1 Download
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The primary healthcare system in Pakistan focuses on providing episodic, disease-based care. Health care for low-middle income communities is largely through a fee-for-service model that ignores preventive and health-promotive services. The growing burden of cardiovascular illnesses requires restructuring of the primary health care system allowing a community-to-clinic model of care to improve patient- and community-level health indicators.
10p vishanshan 27-06-2024 1 1 Download
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Part 2 book "Small animal cardiovascular medicine" includes content: The approach to the patient with cardiac disease; patent ductus arteriosus; septal defects; tetralogy of fallot; pulmonic stenosis; aortic stenosis; congenital abnormalities of the atrioventricular valves; other congenital cardiovascular abnormalities; myxomatous atrioventricular valvular degeneration; primary myocardial disease; hypertrophic cardiomyopathy.
583p dianmotminh03 17-06-2024 1 0 Download
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The aims of primary level are promoting health and preventing occurrence of disease. The aims of secondary level are preventing recurrence and reducing consequences of disease. The aims of tertiary level are reducing progress and limiting impairment of disease.
9p vicarlos 11-06-2024 0 0 Download
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The primary aim of Cerebral Signal Transduction: From First to Fourth Messengers, therefore, is to offer a comprehensive picture of the recent advances made in the signaling field as it relates to neuronal and cere bral function. The current state of progress provides an exciting opportunity for such a comprehensive focus because molecular tools have become available to selectively remove, reduce, or enhance spe cific components in the signaling pathways, e. g. , by interfering with the genes encoding key proteins.
441p vimeyers 29-05-2024 3 2 Download
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This study addresses the elevated prevalence of skin and soft tissue infections (SSTIs) within the pediatric demographic, necessitating a comprehensive inquiry into their varied clinical manifestations. The primary objectives involve the assessment of clinical and laboratory characteristics of SSTIs in children and an exploration of their correlation with treatment efficacy.
5p viambani 21-05-2024 5 1 Download
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Ebook "A clinical guide to the treatment of the human stress response (Third edition)" emphasizes the unique contribution of this longstanding text in the integration of mind/body relationships. The concept of stress, as defined and elaborated in Chapter 1, the primary efferent biological mechanisms of the human stress response, as described in Chapter 2, and the link from stress arousal to disease, as defined in Chapter 3, essentially remains the same. However, updates in microanatomy, biochemistry and tomography are added to these chapters.
489p tracanhphuonghoa1007 22-04-2024 4 2 Download
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This comprehensive review evaluates the advancements, potential, and ethical implications of nanotechnology in medical diagnostics within the U.S. healthcare system. The primary objective was to assess how nano-tools are revolutionizing early disease detection and management. The methodology involved a systematic review of peer-reviewed literature, focusing on studies published between 2000 and 2023.
10p visergey 02-04-2024 3 0 Download
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Recent work has reported that the activation of the p53 pathway in primary cells hampers the efficiency of genome editing by CRISPR/Cas9 via induction of apoptosis or cell cycle arrest. These findings highlight the importance of wholly comprehending cellular responses to programmable nucleases in therapeutically relevant cell types to fulfill the promise of genome editing for therapeutic applications for human diseases.
4p vibransone 28-03-2024 5 2 Download
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Patients diagnosed with high-grade serous ovarian cancer (HGSOC) who received initial debulking surgery followed by platinum-based chemotherapy can experience highly variable clinical responses. A small percentage of women experience exceptional long-term survival (long term (LT), 10+ years), while others develop primary resistance to therapy and succumb to disease in less than 2 years (short term (ST)).
17p vibransone 28-03-2024 2 1 Download
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Diagnosis of primary immunodeficiencies (PIDs) is complex and cumbersome yet important for the clinical management of the disease. Exome sequencing may provide a genetic diagnosis in a significant number of patients in a single genetic test.
15p vibransone 28-03-2024 2 2 Download
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DNA originating from degenerate tumour cells can be detected in the circulation in many tumour types, where it can be used as a marker of disease burden as well as to monitor treatment response. Although circulating tumour DNA (ctDNA) measurement has prognostic/predictive value in metastatic prostate cancer, its utility in localised disease is unknown.
11p vibransone 28-03-2024 3 2 Download
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Solid tumors such as pancreatic ductal adenocarcinoma (PDAC) comprise not just tumor cells but also a microenvironment with which the tumor cells constantly interact. Detailed characterization of the cellular composition of the tumor microenvironment is critical to the understanding of the disease and treatment of the patient.
14p vibransone 28-03-2024 4 2 Download
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Skeletal muscle is one of the primary tissues involved in the development of type 2 diabetes (T2D). The close association between obesity and T2D makes it difficult to isolate specific effects attributed to the disease alone. Therefore, here we set out to identify and characterize intrinsic properties of myocytes, associated independently with T2D or obesity.
12p vioraclene 31-03-2024 2 1 Download
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Hepatic fibrosis is the underlying cause of cirrhosis and liver failure in nearly every form of chronic liver disease, and hepatic stellate cells (HSCs) are the primary cell type responsible for fibrosis. Long noncoding RNAs (lncRNAs) are increasingly recognized as regulators of development and disease; however, little is known about their expression in human HSCs and their function in hepatic fibrosis.
20p vioraclene 31-03-2024 7 2 Download