Progression pattern
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Pyroptosis is a type of programmed cell death mediated by the gasdermin family. Gasdermin B (GSDMB), as a member of gasdermin family, can promote the occurrence of cell pyroptosis. However, the correlations of the GSDMB expression in colorectal cancer with clinicopathological predictors, immune microenvironment, and prognosis are unclear.
13p vishanshan 27-06-2024 1 1 Download
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Part 1 of ebook "Progress in activity-based analysis" provides readers with contents including: contributions to understanding joint relationships among activity and travel variables; a dynamic programming approach for the activity generation and scheduling problem; simulation of daily activity patterns; simulation daily activity patterns through the identification of sequential dependencies; adjustments of activity timing and duration in an agent-based traffic flow simulation;...
249p dongmelo 21-05-2024 2 2 Download
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We aimed to identify the T790M mutation rate and clinical factors predicting the occurrence of acquired T790M mutations in advanced non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations after first- and secondgeneration tyrosine kinase inhibitor (TKI) treatment.
9p vicarlos 16-05-2024 1 0 Download
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Exosomes are promising tools for improving cancer care, but conversely may also contribute to tumor progression. Here, we highlight recently discovered roles of exosomes in modulating immune responses in cancer, with emphasis on exosomal surface proteins and on RNA and DNA content. We also discuss how exosomes could be exploited as biomarkers and delivery vehicles in cancer therapy.
4p vibransone 28-03-2024 2 2 Download
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In cancer, normal epigenetic patterns are disturbed and contribute to gene expression changes, disease onset, and progression. The cancer epigenome is composed of the epigenetic patterns present in the tumor-initiating cell at the time of transformation, and the tumor-specific epigenetic alterations that are acquired during tumor initiation and progression.
19p vibransone 28-03-2024 4 2 Download
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Ebook "Species diversity and community structure: Novel patterns and processes in plants, insects, and fungi" introduces recent progress in the study of species diversity and community structures in terrestrial organisms conducted by three groups at Kyoto University. First, it explains species diversity and the functioning of fungi in Asian regions as outlined by metagenomic approaches using next-generation sequencing technology. The advances in high-throughput sequencing technologies accelerate the speed of species inventorying, especially for microorganisms.
70p manmanthanhla0201 26-02-2024 2 1 Download
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The relatively isolated atrophy of the temporal lobes leads to a clinical radiological pattern, referred to as the temporal variant of frontotemporal dementia. While semantic dementia and behavioral variant frontotemporal dementia are classically related to this syndrome, the logopenic variant of primary progressive aphasia has been less commonly reported.
8p vigojek 02-02-2024 2 1 Download
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Nonalcoholic fatty liver disease affects about 24% of the world’s population and may progress to nonalcoholic steatohepatitis (NASH), cirrhosis, and hepatocellular carcinoma (HCC). While more common in those that are obese, NASH-HCC can develop in lean individuals. The mechanisms by which HCC develops and the role of epigenetic changes in the context of obesity and normal weight are not well understood.
13p vileonardodavinci 23-12-2023 4 2 Download
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Excision repair cross-complementation group 6 like (ERCC6L), a polo-like kinase 1 (PLK1)-interacting checkpoint helicase, confers a high risk of cancer and enhances the progression of a variety of cancers. The present investigation aimed to elucidate the pan-cancer expression patterns of ERCC6L and to examine the possibility of using this gene for patient diagnosis and prognosis.
16p vileonardodavinci 23-12-2023 4 2 Download
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To review our long-term clinical experience, analyze the failure patterns, and give suggestions for target volume delineation of carcinoma showing thymus-like differentiation (CASTLE) treated with intensity-modulated radiotherapy (IMRT).
8p vileonardodavinci 23-12-2023 4 3 Download
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Continued part 1, part 2 of ebook "Material design implementation with AngularJS: UI component framework" provides readers with contents including: Chapter 7 - Forms; Chapter 8 - Lists and alerts; Chapter 9 - Mobile-friendly elements; Chapter 10 - Miscellaneous—icons and ARIA; Chapter 11 - Miscellaneous; Chapter 12 - Responsive design patterns;...
99p dangsovu 20-10-2023 6 5 Download
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We aimed to examine whether patients with de novo and relapsed/progressed stage IIIB–IV non-small cell lung cancer (NSCLC) without epidermal growth factor receptor (EGFR) or anaplastic lymphoma kinase (ALK) mutations have different prognoses.
12p visharma 20-10-2023 6 2 Download
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Liver metastasis is a poor prognostic factor for treatment of advanced cutaneous melanoma with either immunotherapy or targeted therapies. In this study we focused on NRAS mutated melanoma, a cohort with high unmet clinical need.
16p visharma 20-10-2023 6 2 Download
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Over past decades, epidemiological patterns of liver cancer (LC) have changed dramatically. The Global Burden of Disease (GBD) study provides an opportunity for tracking the progress in cancer control with its annual updated reports at national, regional and global level, which can facilitate the health decision-making and the allocation of health resources.
18p vioracle 29-09-2023 6 2 Download
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English Pronunciation in use elementary progresses from individual sounds, through sequences of sounds, and stress in words, to intonation patterns in phrases and sentences. Of course, as soon as learners begin to speak English, they need to begin to develop control of all these features in parallel, but the step-by-step, incremental approach adopted here is designed to facilitate a clear progression and a clear focus on one thing at a time.
94p haojiubujain05 09-08-2023 10 7 Download
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Lafora disease is a rare genetic disorder involving glycogen metabolism disorder. It is inherited by autosomal recessive pattern presenting as a progressive myoclonus epilepsy and neurologic deterioration beginning in adolescence. It is characterized by Lafora bodies in tissues such as brain, skin, muscle, and liver.
5p vigamora 23-05-2023 4 2 Download
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Pancreatitis is an infammatory disorder resulting from the autoactivation of trypsinogen in the pancreas. The genetic basis of the disease is an old phenomenon, and evidence is accumulating for the involvement of synonymous/non-synonymous codon variants in disease initiation and progression.
19p vihagrid 30-01-2023 6 3 Download
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This study found out the patterns of urban heat islands in Hanoi: the heat islands are concentrated as large zones in the high construction density urbans, which are also developed of economy and urbanization; Line forms in suburban areas with medium construction density - where planning is in progress and scatters in the low construction density areas - the slower economic development and urbanization.
12p viwmotors 13-12-2022 8 2 Download
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Reportedly, circular RNA (circRNA) is a key modulator in the development of human malignancies. This work is aimed to probe the expression pattern, biological effects and mechanism of circ_0064288 on hepatocellular carcinoma (HCC) progression.
11p vikolindagrabar 27-07-2022 3 1 Download
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Long non-coding RNAs (lncRNAs) are widely involved in the pathogenesis of cancers. However, biological roles of lncRNAs in occurrence and progression of colorectal cancer (CRC) remain unclear. The current study aimed to evaluate the expression pattern of lncRNAs and messenger RNAs (mRNAs).
11p vikolindagrabar 27-07-2022 4 1 Download