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Regulatory element
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Genomic structural variants (SVs) can affect many genes and regulatory elements. Therefore, the molecular mechanisms driving the phenotypes of patients carrying de novo SVs are frequently unknown.
15p
vibransone
28-03-2024
5
2
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Ebook "Roadmap to sustainable textiles and clothing: Regulatory aspects and sustainability standards of textiles and the clothing supply chain" covers the elements involved in achieving sustainability in textiles and clothing sector. The chapters covered in three volumes of this series title cover all the distinctive areas earmarked for achieving sustainable development in textiles and clothing industry. This third volume highlights the areas pertaining to the regulatory aspects and sustainability standards applicable to textiles and clothing supply chain.
200p
tudohanhtau1006
29-03-2024
2
1
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Genes with multiple co-active promoters appear common in brain, yet little is known about functional requirements for these potentially redundant genomic regulatory elements. SCN1A, which encodes the NaV1.1 sodium channel alpha subunit, is one such gene with two co-active promoters.
22p
vibransone
28-03-2024
5
2
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Enhancers are distal cis-regulatory elements required for cell-specific gene expression and cell fate determination. In cancer, enhancer variation has been proposed as a major cause of inter-patient heterogeneity— however, most predicted enhancer regions remain to be functionally tested.
25p
vibransone
28-03-2024
5
2
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Non-coding regulatory elements (NCREs), such as enhancers, play a crucial role in gene regulation, and genetic aberrations in NCREs can lead to human disease, including brain disorders. The human brain is a complex organ that is susceptible to numerous disorders.
27p
vibransone
28-03-2024
7
2
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Neuropsychiatric disorders afflict a large portion of the global population and constitute a significant source of disability worldwide. Although Genome-wide Association Studies (GWAS) have identified many disorderassociated variants, the underlying regulatory mechanisms linking them to disorders remain elusive, especially those involving distant genomic elements.
15p
viellison
28-03-2024
5
2
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his was a very exciting and, at the same time, very surprising discovery. It was exciting because if true, it would have marked the detection of the first planet outside of our solar system. It was surprising because the planet-hosting star is the primary of a binary system with a separation less than 19 AU, a distance comparable to the planetary distances in our solar system.
334p
duongthandue0501
28-02-2024
2
1
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Prioritizing genes that underlie complex brain disorders poses a considerable challenge. Despite previous studies have found that they shared symptoms and heterogeneity, it remained difficult to systematically identify the risk genes associated with them.
20p
vicwell
29-02-2024
1
1
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Ebook "Untranslated gene regions and other non-coding elements: Regulation of eukaryotic gene expression" pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.
63p
manmanthanhla0201
26-02-2024
5
1
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Part 2 book "Advanced nutrition and human metabolism" includes content: The water soluble vitamins, the fat soluble vitamins, macrominerals, microminerals, ultratrace elements, experimental design and critical interpretation of research.
292p
muasambanhan08
23-02-2024
7
1
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Part 2 book "Introduction to human nutrition" includes content: Minerals and trace elements, measuring food intake, food composition, food and nutrition - policy and regulatory issues, nutrition research methodology, food safety - a public health issue of growing importance, food and nutrition related diseases - the global challenge.
184p
muasambanhan08
23-02-2024
4
2
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Ebook "Sulfur assimilation and abiotic stress in plants" discusses the aspects of sustainable crop production with sulfur, the importance of sulfur metabolites and sulfur metabolizing enzymes in abiotic stress management in plants. Sulfur is one of the four major essential elements necessary for the plant life cycle. Its assimilation in higher plants and its reduction in metabolically important sulfur compounds are crucial factors determining plant growth and vigor and resistance to stresses.
373p
tachieuhoa
28-01-2024
3
2
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Part 2 book "Avian embryology" includes content: Time lapse imaging of the early avian embryo, gain and loss of function approaches in the chick embryo, manipulation and electroporation of the avian segmental plate and somites in vitro, generating transgenic quail using lentiviruses, dissection of chick genomic regulatory regions, computational approaches to finding and analyzing cis regulatory elements.... and other contents.
199p
oursky05
20-09-2023
3
2
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Given the abundance of new genomic projects and gene annotations, researchers trying to pinpoint causal genetic variants are faced with a challenging task of how to efficiently integrate all current genomic information.
13p
vinarcissa
21-03-2023
7
1
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This thesis presents a pro–active research work motivated by the prospect of the imminent implementation of the regulatory requirement for pedestrian protection, Global Technical Regulation–9 (GTR–9) (United Nations Economic Commission for Europe 1998) in the near future. To meet the performance criteria for pedestrian protection head impact, it is vital to incorporate the required design parameters into the hood design process at an early stage. These main design parameters are architectural and changing them late in the vehicle design process is very expensive and difficult to implement.
244p
runthenight05
01-03-2023
4
3
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The purpose of this paper is to explore a best practice framework for the regulation of payment services. It will discuss and assess some models as potential law reform concepts to be further developed. This paper will consider some possible models for the regulation of payment services involving the key elements of disclosure, minimum standards, prudential regulation and conduct licensing. It will also discuss supervision of the inter-bank payment system and a basic fair play regime. A possible regulatory model will be suggested as a contribution to future debate.
63p
runthenight04
02-02-2023
3
1
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The expression of genes involved in regulating adipogenesis and lipid metabolism may affect economically important fatness traits in pigs. Allele-specific expression (ASE) reflects imbalance between allelic transcript levels and can be used to identify underlying cis-regulatory elements.
9p
vihagrid
30-01-2023
6
3
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Both classes of transposable elements (DNA and RNA) are tightly regulated at the transcriptional level leading to the inactivation of transposition via epigenetic mechanisms. Due to the high copies number of these elements, the hypothesis has emerged that their regulation can coordinate a regulatory network of genes.
12p
vihagrid
30-01-2023
7
3
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Auxins play an important role in plant growth and development; the auxins responsive gene; auxin/ indole-3-acetic acid (Aux/IAA), small auxin-up RNAs (SAUR) and Gretchen Hagen3 (GH3) control their mechanisms. The GH3 genes function in homeostasis by the catalytic activities in auxin conjugation and bounding free indole-3- acetic acid (IAA) to amino acids.
17p
vihagrid
30-01-2023
8
3
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We develop a method called open chromatin enrichment and network Hi-C (OCEAN-C) for antibody-independent mapping of global open chromatin interactions. By integrating FAIRE-seq and Hi-C, OCEAN-C detects open chromatin interactions enriched by active cis-regulatory elements.
14p
vimichaelfaraday
25-03-2022
10
3
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