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Reproducible research
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The research approaches the research object by synthesizing, analysing and comparing different input data sources: maps, text documents, survey results, photographic data. Then, the graphics of urban architectural space of ancient cities are reproduced in different steps, from simple to detailed.
7p
viplato
02-01-2024
4
2
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Ebook "Circular RNAs: Methods and protocols" provides established approaches for identifying, characterizing, and manipulating circRNAs in vitro, in vivo, and in silico. Chapters highlight the breakthroughs and the challenges in this new field of research. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
223p
lucchinguyen
28-12-2023
3
2
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Despite their heterogeneity, the current standard preoperative radiotherapy regimen for localized highgrade soft tissue sarcoma (STS) follows a one fits all approach for all STS subtypes. Sarcoma patient-derived threedimensional cell culture models represent an innovative tool to overcome challenges in clinical research enabling reproducible subtype-specific research on STS.
10p
visharma
20-10-2023
4
2
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Electronic health records (EHRs) are a rich source of information on human diseases, but the information is variably structured, fragmented, curated using different coding systems, and collected for purposes other than medical research. We describe an approach for developing, validating, and sharing reproducible phenotypes from national structured EHR in the United Kingdom with applications for translational research.
15p
visteverogers
24-06-2023
4
2
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Lack of reproducibility in medical studies is a barrier to the generation of a robust knowledge base to support clinical decision-making. In this paper we outline the Medical Information Mart for Intensive Care (MIMIC) Code Repository, a centralized code base for generating reproducible studies on an openly available critical care dataset.
8p
visteverogers
24-06-2023
7
2
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Bioinformatics publications typically include complex software workflows that are difficult to describe in a manuscript. We describe and demonstrate the use of interactive software notebooks to document and distribute bioinformatics research.
9p
visteverogers
24-06-2023
8
2
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Geocoding and characterizing geographic, community, and environmental characteristics of study participants is frequently done in epidemiological studies. However, participant addresses are identifiable protected health information (PHI) and geocoding must be conducted in a Health Insurance Portability and Accountability Act–compliant manner.
6p
visteverogers
24-06-2023
5
2
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Many research fields, including psychology and basic medical sciences, struggle with poor reproducibility of reported studies. Biomedical and health informatics is unlikely to be immune to these challenges. This paper explores replication in informatics and the unique challenges the discipline faces.
6p
visteverogers
24-06-2023
3
2
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Diane Forsythe and other feminist scholars have long shown how system builders’ tacit assumptions lead to the systematic erasure of certain users from the design process. In spite of this phenomena being known in the health informatics literature for decades, recent research shows how patient portals and electronic patients health records continue to reproduce health inequalities in Western societies.
8p
vighostrider
25-05-2023
7
2
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In several fish species homozygous and heterozygous clonal lines have been produced using gynogenetic and androgenetic techniques. These lines are standardized and can be reproduced over generations. In rainbow trout such lines have existed for decades and has become important research tools in genome studies as well as in studies of commercially important traits.
10p
vihagrid
30-01-2023
7
3
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The accompanying redistribution of resources could be an opportunity for society to overcome existing unjust power relations, such as gender inequalities, instead of reproducing these structures. To achieve this, there must be a better understanding of the effects of transformation dynamics on inequalities.
14p
huangminghao_1902
27-02-2022
25
2
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Skin marker-based three-dimensional kinematic gait analysis were commonly used to assess the functional performance and movement biomechanics of the pelvic limb in dogs. Unfortunately, soft tissue artefact would compromise the accuracy of the reproduced pelvic limb kinematics.
9p
vigalileogalilei
28-02-2022
14
1
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The aims of the study were to assess the feasibility, repeatability, and reproducibility of SE for imaging the distal attachment of the joint capsule (DJC) of metacarpophalangeal joints in sound horses (Group S) and in horses with metacarpophalangeal OA (Group P) and to evaluate differences in the elastosonographic patterns of these horses.
10p
vidarwin
23-02-2022
9
1
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There is a growing interest in the scientific community to use computer-based software programs for the quantification of cells during physiological and pathophysiological processes. Drawbacks of computer-based methods currently used to quantify immunohistochemical staining are the complexity of use, expense of software and overly-simplified descriptions of protocol thereby limiting reproducibility.
8p
vigandhi
23-02-2022
9
1
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Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve the reporting of animal research. They consist of a checklist of information to include in publications describing in vivo experiments to enable others to scrutinise the work adequately, evaluate its methodological rigour, and reproduce the methods and results.
7p
vigandhi
23-02-2022
13
1
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Microbiome research has grown exponentially over the past several years, but studies have been difficult to reproduce across investigations. Relevant variation in measurements between laboratories, from a variety of sources, has not been systematically assessed.
6p
viaristotle
29-01-2022
11
0
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Rats have been widely used as experimental animals when performing fundamental research because they are economical, rapidly reproducing, and heal quickly. While the rat interbody fusion model has been applied in basic studies, existing rat models generally have shortcomings, such as insufficiently simulating clinical surgery.
9p
vimackenziebezos
30-11-2021
6
1
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In contrast with traditional nuclear gene transformation, transplastomic technology has opened a new horizon for the transgenic plant research that offers several beneficial aspects including the convenient use of transgene stacking and the generation of high expression levels of foreign proteins. However, this technology has been well adopted and established in tobacco, the introduction and adoption of cost-effective, swift, and reproducible protocol for in vitro regeneration of transplastomic potato is challenging and laborious.
11p
hanthienngao
30-11-2021
9
1
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Research objects: The thesis focused on economic research in Nam Dan District, Nghe An Province under the Nguyen Dynasty in the period 1802 - 1884. However, to reproduce the economic situation of Nam Dan in a systematic and comprehensive manner, ensuring objectivity, in terms of both chronology and synchronicity, we have reserved a part of the summary of factors affecting Nam Dan's economy as well as the economic situation in the area before 1802.
27p
prisonbreak123
21-05-2021
29
4
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Peripheral quantitative computed tomography (pQCT) is an established technology that allows for the measurement of the material properties of bone. Alterations to bone architecture are associated with an increased risk of fracture. Further pQCT research is necessary to identify regions of interest that are prone to fracture risk in people with chronic diseases.
6p
viannito2711
20-04-2021
10
2
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