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SCID mice
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The tumorigenesis of infused umbilical cord mesenchymal stem cells (UC-MSCs) is being preclinically evaluated. Injected hUC-MSCs were not tumorigenic and did not significantly promote or inhibit solid or hemato‑ logical tumor growth or metastasis in NOD SCID mice.
13p
viangelamerkel
27-07-2022
4
1
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Hepatocellular carcinoma (HCC) is one of the leading causes of cancer mortality in the world. Therefore, more and more studies are developing novel therapies to treat this disease. The pre-clinical trials on animals are a vital step to evaluate the efficacy as well as side effects of these novel therapies. Hence, this study aimed to develop the murine model of HCC using 3 kinds of mice: NOD/SCID, nude and Balb/c mice.
7p
larachdumlanat127
02-01-2021
12
2
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The Wnt/β-catenin signaling pathway is an evolutionary conserved pathway, which has important functions in vertebrate early development, axis formation, cellular proliferation and morphogenesis.
10p
vibaku2711
22-07-2020
10
1
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Pharmacokinetics of meloxicam was studied following its single dose intraperitoneal administration alone and administered with erlotinib and/or metformin in SCID mice.
9p
quenchua4
06-04-2020
28
1
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The third section of this book is ‘Adeno-associated-virus Vector’. Chapter nine by Sun et al. introduces the adeno-associated virus (AAV) mediated β-thalassemia gene therapy. Human hematopoietic stem cells (HSCs) were obtained from β-thalassemia patients, transfected with the recombinant AAV containing β-globin gene. The transfected cells were then transplanted into Nude/SCID mice, and the long term expression of β-globin in vivo was examined. In the tenth chapter, Korecka et al. compare AAV serotypes for gene delivery to dopaminergic neurons in the substantia nigra (SN)....
356p
kmkmkmkmkm
08-09-2012
58
4
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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Human cytomegalovirus UL27 is not required for viral replication in human tissue implanted in SCID mice
3p
dauphong7
13-01-2012
41
3
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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " Cigarette smoke-induced pulmonary emphysema in scid-mice. Is the acquired immune system required?...
13p
toshiba13
22-10-2011
53
2
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New Concepts in the Development of Cancer Therapeutics Cancer Stem Cells It has long been recognized that only a small proportion of the cells within a tumor are capable of initiating colonies in vitro or of forming tumors at high efficiency when injected into immunocompromised NOD/SCID mice. Current work indicates that human acute and chronic myeloid leukemias (AML and CML) have a small population of cells (
5p
konheokonmummim
03-12-2010
80
4
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