Sequencing instruments

Genome-wide association studies have shown unequivocally that common complex disorders have a polygenic genetic architecture and have enabled researchers to identify genetic variants associated with diseases. These variants can be combined into a polygenic risk score that captures part of an individual’s susceptibility to diseases.

11p vibransone 28-03-2024 7 1   Download

Part 1 of ebook "Asymptotic theory for econometricians (Revised edition)" provide readers with content including: Chapter 1 - The linear model and instrumental variables estimators; Chapter 2 - Consistency; Chapter 3 - Laws of large numbers; Chapter 4 - Asymptotic normality;...

121p dieptieuung 19-07-2023 7 2   Download

Nanopore sequencing is a rapidly maturing technology delivering long reads in real time on a portable instrument at low cost. Not surprisingly, the community has rapidly taken up this new way of sequencing and has used it successfully for a variety of research applications.

11p vigalileogalilei 27-02-2022 10 1   Download

RNA sequencing using the latest single-molecule sequencing instruments produces reads that are thousands of nucleotides long. The ability to assemble these long reads can greatly improve the sensitivity of long-read analyses. Here we present StringTie2, a reference-guided transcriptome assembler that works with both short and long reads.

13p vielonmusk 30-01-2022 9 0   Download

The present study focused on isolation, identification, and evaluation of glass biodeterioration properties such as organic acid and exopolysaccharide production of fungal strain Chaetomium globosum TTHF1-3 isolated from lens of optical instrument collected at Thai Hoa, Nghe An province.

9p meyerowitz 25-12-2021 10 0   Download

Next-generation sequencing (NGS) has revolutionized almost all fields of biology, agriculture and medicine, and is widely utilized to analyse genetic variation. Over the past decade, the NGS pipeline has been steadily improved, and the entire process is currently relatively straightforward. However, NGS instrumentation still requires upfront library preparation, which can be a laborious process, requiring significant hands-on time.

6p vibeauty 23-10-2021 11 0   Download

The use of light of different wavelengths has grown popular in the poultry industry. An optimum wavelength is believed to improve pigeon egg production, but little is known about the role of microRNAs (miRNAs) in the effects of monochromatic light on ovarian pigeon function. Herein, we harvested ovaries from pigeons reared under monochromatic light of different wavelength and performed deep sequencing on various tissues using an Illumina Solexa high-throughput instrument.

9p vibeauty 23-10-2021 8 0   Download

Oxford Nanopore Technologies’ instruments can sequence reads of great length. Long reads improve sequence assemblies by unambiguously spanning repetitive elements of the genome.

12p vilichoo2711 23-06-2021 15 1   Download

The development of next-generation sequencing instruments has led to the generation of millions of short sequences in a single run. The process of aligning these reads to a reference genome is time consuming and demands the development of fast and accurate alignment tools.

25p viwyoming2711 16-12-2020 10 1   Download

Arguably the most basic step in the analysis of next generation sequencing data (NGS) involves the extraction of mappable reads from the raw reads produced by sequencing instruments. The presence of barcodes, adaptors and artifacts subject to sequencing errors makes this step non-trivial.

8p vikentucky2711 26-11-2020 8 0   Download

RNA-Seq technology is routinely used to characterize the transcriptome, and to detect gene expression differences among cell types, genotypes and conditions. Advances in short-read sequencing instruments such as Illumina Next-Seq have yielded easy-to-operate machines, with high throughput, at a lower price per base.

7p vijisoo2711 27-10-2020 14 0   Download

Next generation sequencing instruments are providing new opportunities for comprehensive analyses of cancer genomes. The increasing availability of tumor data allows to research the complexity of cancer disease with machine learning methods.

10p vicolorado2711 23-10-2020 9 1   Download

Typical experimental design advice for expression analyses using RNAseq generally assumes that single-end reads provide robust gene-level expression estimates in a cost-effective manner, and that the additional benefits obtained from paired-end sequencing are not worth the additional cost.

11p vicolorado2711 22-10-2020 12 1   Download

: Fragmentation at random nucleotide locations is an essential process for preparation of DNA libraries to be used on massively parallel short-read DNA sequencing platforms. Although instruments for physical shearing, such as the Covaris S2 focused-ultrasonicator system.

13p viuchiha2711 21-04-2020 6 0   Download

The rapid emergence of multiresistant microbial pathogens is a serious threat to human health. Extended spectrum beta lactamase (ESBL)-producing Escherichia coli is a superbug causing worldwide outbreaks, CTX-M has become the most commonly detected ESBL genotype; these enzymes have become predominant worldwide, the most common type of CTX-M reported in various geographic regions is CTX-M15. A total of 80 Escherichia coli (E. coli) isolates were recovered from different clinical samples of intensive care units (ICUs) patients.

13p nguathienthan2 26-12-2019 17 1   Download

Biosystems and Biomaterials Division. The primary objective is to collaborate with or conduct research consistent with division projects in standards, measurement methods, and theoretical models that improve understanding and prediction of complex biological processes associated with environmental health, human health, and cell-based manufacturing.

130p thamgiacongdong 02-05-2013 38 5   Download

Spreadsheets provide one of the most easily learned routes to scientific computing. This book uses Excel®, the most powerful spreadsheet available, to explore and solve problems in general and chemical data analysis. It follows the usual sequence of college textbooks in analytical chemistry: statistics, chemical equilibria, pH calculations, titrations, and instrumental methods such as chromatography, spectrometry, and

501p mylan23 15-04-2013 143 33   Download

Data is increasingly generated by instruments that monitor the environment – telescopes looking at the heavens, DNA sequenc- ers decoding molecules, bar-code readers watching passing freight-cars, patient monitors watching the life-signs of a person in the emergency room, cell-phone and credit-card systems look- ing for fraud, RFID scanners watching products flow through the supply chain, and smart-dust sensing its environment. In each of these cases, one wants to compare...

15p yasuyidol 02-04-2013 64 4   Download

Banking sector reforms have been sequenced to correspond with changing regulations of the foreign exchange market. The government has allowed the exchange rate to gradually float (as opposed to a “crawling” peg), and full current account convertibility has been introduced, with de facto capital account convertibility for nonresidents, and calibrated liberalization for residents.

46p enter1cai 16-01-2013 64 4   Download

The LabVIEW Tutorial contains the information you need to get started with the Laboratory Virtual Instrument Engineering Workbench (LabVIEW) software package. LabVIEW simplifies scientific computation, process control, and test and measurement applications, and you can also use it for a wide variety of other programming applications. This manual gives you an overview of the fundamental concepts of LabVIEW, and includes lessons to teach you what you need to know to build your own virtual instruments (VIs) as quickly as possible. This manual does not explain every LabVIEW feature.

0p vinhtk7ce 06-07-2012 148 29   Download