Sequestration

Determinants for desensitization and sequestration of G protein-coupled receptors often contain serine or threonine residues located in their C-ter-mini. The sequence context, however, in which these residues have to appear, and the receptor specificity of these motifs are largely unknown.

12p awards 05-04-2013 46 3   Download

The building blocks of most signal transduction pathways are pairs of enzymes, such as kinases and phosphatases, that control the activity of pro-tein targets by covalent modification. It has previously been shown [Gold-beter A & Koshland DE (1981)Proc Natl Acad Sci USA78, 6840–6844] that these systems can be highly sensitive to changes in stimuli if their cata-lysing enzymes are saturated with their target protein substrates.

12p inspiron33 26-03-2013 51 5   Download

To elucidate the architectural principle of protein structure, we focused on sequestration from solvent, which is a common characteristic of folding and self-associative precipitation. Because protein solubility can be regarded as a basis for the potential ability to sequester from solvent, we assume that poorly soluble proteins tend not only to precipitate, but also to form solution structures.

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The role of non-B DNA in the function and stability of genomes has become generally appreciated in recent years. It is now evident that DNA also encodes for spatial structures that are involved in gene regulation, replication and recombination.

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The ability of mitochondria to sequester and retain divalent cations in the form of precipitates consisting of organic and inorganic moieties has been known for decades. Of these cations, Ca 2+ has emerged as a major player in both signal transduction and cell death mechanisms, and, as a conse-quence, the importance of mitochondria in these processes was soon recog-nized.

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Calcium is an extraordinarily versatile signaling ion, encoding cellular responses to a wide variety of external stimuli. In neurons, mitochondria can accumulate enormous amounts of calcium, with the consequence that mitochondrial calcium uptake, sequestration and release play pivotal roles in orchestrating calcium-dependent responses as diverse as gene transcrip-tion and cell death.

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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:"HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment...

16p toshiba15 24-10-2011 50 5   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " Sequestration and homing of bone marrow-derived lineage negative progenitor cells in the lung during pneumococcal pneumonia...

10p toshiba12 21-10-2011 43 2   Download

Tuyển tập các báo cáo nghiên cứu về lâm nghiệp được đăng trên tạp chí lâm nghiệp Original article đề tài: "The contribution of wood products to carbon sequestration in Portugal"

7p toshiba5 19-09-2011 47 5   Download

Tuyển tập các báo cáo nghiên cứu về lâm nghiệp được đăng trên tạp chí lâm nghiệp Original article đề tài: Integrating revenues from carbon sequestration into economic breeding objectives for Eucalyptus globulus pulpwood production...

8p toshiba5 15-09-2011 55 4   Download

Define ecological biochemistry. • Explain biochemical adaptation and the roles of secondary compounds. • Describe detoxification and the primary metabolic pathways in plants and animals. • Explain the key processes and factors involved in biotransformation & biodegradation. • Explain the concepts of sequestration, bioaccumulation, and biomagnification. • Contrast different forms of ecological biochemical interaction.

8p nguyenvanquan037 07-01-2011 70 4   Download