Several classes and the domain knowledge

This paper proposes a new multiclass approach called multi-level (hierarchical) learning architecture (MLA). It addresses the binary classification tasks within the framework of a hierarchical strategy. It does so by accounting for the interaction between several classes and the domain knowledge.

24p meriday 20-04-2019 22 1   Download

A new approach of predicting structural classes of protein domain sequences is presented in this paper. Besides the amino acid composition, the composition of several dipeptides, tripeptides, tetrapeptides, pentapeptides and hexapeptides are taken into account based on the step-wise discriminant analysis. The result of jackknife test shows that this new approach can lead to higher pre-dictive sensitivityand specificityfor reduced sequence similaritydatasets.

7p research12 23-04-2013 28 2   Download