Single cell

The process of neural stem cell (NSC) differentiation into neurons is crucial for the development of potential cell-centered treatments for central nervous system disorders. However, predicting, identifying, and anticipating this differentiation is complex. In this study, we propose the implementation of a convolutional neural network model for the predictable recognition of NSC fate, utilizing single-cell brightfield images.

7p viengfa 28-10-2024 1 1   Download

To evaluate the effectiveness of radiotherapy on overall survival (OS) and identify factors affecting survival outcomes in patients with stage III non-small cell lung cancer (NSCLC) where surgery is not feasible.

11p viavatis 29-08-2024 4 1   Download

Pembolizumabis an immune check-point inhibitor to be targeted for Programmed cell death 1 (PD-1). It has been shown promising efficacy to various types of cancer. In Vietnam, pembrolizumab has been available since early of 2018. We has performed to treat certain types of cancer with pembrolizumabby now, herein we report the early experience with pembrolizumabin single institute in Vietnam.

4p vinatisu 29-08-2024 5 1   Download

The methanol extracts as well as some compounds from this plant exhibited anti-inflammatory, antimicrobial activity, antioxidant, hepatoprotective and anti-cancer effect, and antiosteoporotic. On going to search for bioactive components from the Vietnamese plant, this paper reported the isolation of seven phenolic compounds including one new from the aerial parts of A. ilicifolius. The cytotoxic activity of the isolates against two cancer cell lines (HepG2 and SK-LU1) were also screened and reported herein.

5p dianmotminh02 03-05-2024 8 2   Download

The overall aim of this research project is thus to study the concept of integrating a solid-state metal hydride electrode and a unitised regenerative fuel cell into a single system, and investigate its performance as a reversible store for electrical energy.

148p runthenight07 01-03-2023 10 3   Download

Organogenesis is crucial for proper organ formation during mammalian embryonic development. However, the similarities and shared features between different organs and the cellular heterogeneity during this process at single-cell resolution remain elusive.

20p vimichaelfaraday 25-03-2022 19 1   Download

Human pluripotent stem cells (hPSCs) provide powerful models for studying cellular differentiations and unlimited sources of cells for regenerative medicine. However, a comprehensive single-cell level differentiation roadmap for hPSCs has not been achieved.

19p vimichaelfaraday 25-03-2022 14 1   Download

Single-cell analysis is a powerful tool for dissecting the cellular composition within a tissue or organ. However, it remains difficult to detect rare and common cell types at the same time. Here, we present a new computational method, GiniClust2, to overcome this challenge.

13p vimichaelfaraday 25-03-2022 12 1   Download

There is no unified treatment standard for patients with extranodal NK/T-cell lymphoma (ENKTL). Cancer neoantigens are the result of somatic mutations and cancer-specific. Increased number of somatic mutations are associated with anti-cancer effects.

12p vielonmusk 21-01-2022 11 0   Download

Overcoming drug resistance is critical for increasing the survival rate of prostate cancer (PCa). Doc‑ etaxel is the first cytotoxic chemotherapeutical approved for treatment of PCa. However, 99% of PCa patients will develop resistance to docetaxel within 3 years. Understanding how resistance arises is important to increasing PCa survival.

14p vielonmusk 21-01-2022 11 1   Download

This paper investigates how PbS coating layers influence the characteristics of GaAs single junction solar cells through I-V characteristic measurements, optical reflectance spectra, and quantum efficiencies.

6p tamynhan6 14-09-2020 14 2   Download

Influence of substitution of 3d metals for Mn on properties of La0.67Ca0.33Mn0.9 TM0.1O3 (TM = Fe, Co, Ni) compounds was studied. Ferromagnetic – paramagnetic and metals – insulator transitions were significantly affected by Mn-site substitution. However, no observable difference was found in their crystal structure from X-ray diffraction analysis. At room temperature the structure characterization of these compounds gave the single phase and structure is the distortion orthorhombic cell with space group symmetry Pnma.

12p 12120609 01-06-2020 13 2   Download

Bài 8 phân tích, tổ chức và chia sẻ Workbooks thuộc bộ bài giảng Microsoft office excel 2010 trình bày nội dung về: sắp xếp dữ liệu single-level; sắp xếp dữ liệu multi-level; lọc thông tin; tạo phạm vị được đặt tên; sửa đổi và xóa named ranges; chèn siêu liên kết... Mời các bạn tham khảo.

0p tranhanh9196 12-10-2018 64 5   Download

The result showed that only 6% single cancer cells developed into tumorspheres during culture process. Then, flow cytometry and immunofluorescence analysis was carried out to evaluate the expression of CSC markers CD44 and ALDH in samples taken from tumorspheres which arose from gastric CSCs. The results showed that gastric CSCs formed tumorspheres in 3D culture condition with a high expression of 92% and 40,1% for markers CD44 and ALDH, respectively.

8p cumeo4000 01-08-2018 25 0   Download

This paper presents new carrier-based PWM modulations to control this dual topology for optimum operation. In terms of power sources, this cascaded inverter is operated either from isolated dc sources (series power cells) or from a single dc source. Computational simulation and experimental validation are given to verify the proposed techniques.

11p binhminhmuatrenngondoithonggio 09-06-2017 44 2   Download

This paper discussed the influence of goblet cell in co-infected host on elimination of Nippostrongylus brasiliensis. For this purpose, Nippostrongylus brasiliensis and Eimeria vermiformis were infected to ICR mice, expulsion of the worm were delayed in co-infected group compare to single infected group and associated with the changes of goblet cell number.

10p nganga_06 29-09-2015 29 3   Download

Người ta có thể tiến hành xử lý và chọn lọc tế bào thực vật ở ba mức độ cấu trúc chính: callus, tế bào đơn (single cell) và tế bào trần. Trong phạm vi công nghệ (nuôi cấy) tế bào thực vật, người ta thường tập trung các nghiên cứu cho mục đích chọn dòng tế bào sản xuất dư thừa (over production) các loại sản phẩm chủ yếu là các amino acid và các hợp chất tự nhiên.

9p butmaulam 23-09-2013 290 18   Download

Các loại đột biến đơn gene (single - gene mutation) .Đột biến gene (gene mutation) xảy ra khi có sự thay đổi trong trình tự của các nucleotide trên DNA. Chúng có thể xảy ra ở các tế bào dòng sinh dục (germline cell) hoặc các tế bào sinh dưỡng (somatic cell).

6p butmauvang 29-08-2013 78 3   Download

In the course of trying to understand the pathogenesis of leishmaniasis in relation to extracellular matrix (ECM) elements, laminin, a major ECM protein, has been found to bind saturably and with high affinity to a 67-kDa cell surface protein of Leishmania donovani. This interaction involves a single class of binding sites, which are ionic in nature, conformation-dependent and possibly involves sulfhydryls. Binding activity was significantly enhanced by Zn2+, an effect possibly mediated through Cys-rich zinc finger-like sequences on laminin....

8p system191 01-06-2013 41 4   Download

To establish stable cell lines that produce recombinant multisubunit proteins, it is usually necessary to cotransfect cells with several independent gene constructs. Here, we show that a stepwise fusion of individually transfected cells, results in a fused cell-line that secretes a complete multisubunit protein. Functional expression of recombinant multisubunit proteins may require a defined expression ratio between each protein subunit. The cell-fusion technology described allows a predefined expression level of each subunit.

6p system191 01-06-2013 34 3   Download