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Single nucleotide polymorphism microarray
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The recommended genomic DNA input requirements for whole genome single nucleotide polymorphism microarrays can limit the scope of molecular epidemiological studies. We performed a large-scale evaluation of whole genome amplified DNA as input into high-density, whole-genome Illumina® Infinium® SNP microarray.
10p
vibeauty
23-10-2021
9
1
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By definition, effect of synonymous single-nucleotide variants (SNVs) on protein folding and function are neutral, as they alter the codon and not the encoded amino acid. Recent examples indicate tissue-specific and transfer RNA (tRNA)-dependent effects of some genetic variations arguing against neutrality of synonymous SNVs for protein biogenesis.
12p
visilicon2711
20-08-2021
10
1
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Genomic information allows population relatedness to be inferred and selected genes to be identified. Single nucleotide polymorphism microarray (SNP-chip) data, a proxy for genome composition, contains patterns in allele order and proportion.
21p
vikentucky2711
26-11-2020
9
0
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Gene expression microarrays measure the levels of messenger ribonucleic acid (mRNA) in a sample using probe sequences that hybridize with transcribed regions. These probe sequences are designed using a reference genome for the relevant species.
8p
vikentucky2711
24-11-2020
8
1
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One aspect in which RNA sequencing is more valuable than microarray-based methods is the ability to examine the allelic imbalance of the expression of a gene. This process is often a complex task that entails quality control, alignment, and the counting of reads over heterozygous single-nucleotide polymorphisms.
6p
vikentucky2711
24-11-2020
13
1
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Our study was aimed to explore the clinical implication of chromosome microarray analysis (CMA) in genetically etiological diagnosis of children with congenital heart disease (CHD).
9p
videshiki2711
19-02-2020
7
0
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To meet the emerging needs of genomics, proteomics, and the other omics, microarrays have become unique and important tools for high-throughput analysis of biomolecules. Microarray technology provides a highly sensitive and precise technique for obtaining information from biological samples. It can simultaneously handle a large number of analytes that may be processed rapidly.
469p
bachduong1311
10-12-2012
40
3
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