Steroid resistance in children
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objectives: To describe the epidemiologically clinical and biological characteristics of steroid - dependent and steroid - resistant INS in children at the Hai Phong Children’s Hospital. To evaluate the efficacy of the combination of intravenous cyclophosphamide and prednisolone in treatment of steroid - dependent and steroid - resistant INS in children. To describe changes in several immune parameters before and after treatment in these patients.
29p extraenglish 24-05-2021 7 2 Download
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The aim of this study is to compare the levels of TNF-α in children with nephrotic syndrome and healthy control children and the correlation of TNF-α with clinical feature of NS. Fifty children with NS were divided into four groups: 14 steroid sensitive infrequent relapse (SSIFR), 12 steroid sensitive frequent relapse (SSFR), 9 steroid resistance (SR) and 15 newly diagnosis (ND) compared to twenty-five unrelated healthy children. The serum IL-13 levels for NS patients and healthy control children were measured by R&D quantitative ELISA kit.
7p kethamoi5 03-06-2020 24 2 Download
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Idiopathic nephrotic syndrome (INS) is a major manifestation of chronic idiopathic glomerulonephritis and a common disease in children. The cause and pathogenesis of the disease have not been clarified so far. The treatment is usually a longterm process, from a few months to several years, even decades, including the period of hospitalisation, outpatient treatment period and follow-up period after treatment. The INS patients are negatively affected by the disease and its treatment process.
4p caygaocaolon1 13-11-2019 35 1 Download