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Studies on fucoidan

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  • An experiment was conducted to study the influence of dietary fucoidan from brown seaweeds viz., Padina tetrastromatica and Sargassum oligocystum on the innate immunity and disease resistance of fish Oreochromis mossambicus. Fucoidan was supplemented with fish feed at different concentrations such as 0.1, 0.2 and 0.3% to observe hematological changes and non-specific immunological properties for a period of 60 days.

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  • On the basis of chemical and spectral analyses, the fucoidan fractions obtained were found to be the sulfated fucogalactans containing sulfate ester groups and uronic acid, and composed essentially of fucose and galactose, as well as a minor amount of other sugars. The polysaccharide fractions were tested for anticancer activity. The primarily obtained results showed that all fucoidan fractions isolated from S. swartzii demonstrate bioactivity effects against cancer cells, while fraction F5 with a highest sulfate content exhibits the strongest antiinvasion activity.

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  • The comparative study of the content and structure characteristics of fucoidans from five Sargassum brown seaweed species in the south provinces of Vietnam was conducted. The yield of fucoidans was ca. 4% (w/w) based on dry seaweed. The percentage of sulfate and uronic acid content was determined by Scott method. Fucoidans were hydrolyzed with trifluoroacetic acid, acetylated and their L-fucose, D-xylose, D-rhamnose, D-mannose, D-glucose, and D-galactose contents were identified by gas chromatography. All polysaccharides isolated from Sargassum polycystum C. Agardh, S. mcclurei Setchell, S.

    pdf4p uocvong04 24-09-2015 76 8   Download

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