Surprisingly little

Although there are over 400,000 people each year in the United States alone who suffer from traumatic injury to the central nervous system (CNS), no phar­ macological treatment is currently available. Considering the enormity of the problem in terms of human tragedy as well as the economic burden to families and societies alike, it is surprising that so little effort is being made to develop treatments for these disorders.

399p vimeyers 29-05-2024 4 2   Download

Colorectal cancer is the 2nd leading cause of cancer-related deaths with few patients benefiting from biomarker-guided therapy. Mutation expression is essential for accurate interpretation of mutations as biomarkers, but surprisingly, little has been done to analyze somatic cancer mutations on the expression level. We report a large-scale analysis of allele-specific mutation expression.

18p vibransone 28-03-2024 2 2   Download

Ebook "Essentials of oceanography (Fifth edition)" was written to provide an interesting, clear, current, and reasonably comprehensive overview of the marine sciences. It was designed for students who are curious about Earth’s largest feature, but who may have little formal background in science. Oceanography is broadly interdisciplinary; students are invited to see the connections between astronomy, economics, physics, chemistry, history, meteorology, geology, and ecology—areas of study they once considered separate.

463p cotieubac1004 15-03-2024 3 0   Download

The soil environment is responsible for sustaining most terrestrial plant life, yet we know surprisingly little about the important functions carried out by diverse microbial communities in soil. Soil microbes that inhabit the channels of decaying root systems, the detritusphere, are likely to be essential for plant growth and health, as these channels are the preferred locations of new root growth.

19p viarchimedes 26-01-2022 6 1   Download

Surprisingly little is known about asthma control among asthmatics who smoke. The aim of this cross-sectional study was to investigate asthma symptom control according to the GINA guidelines among asthmatics with a clinically significant smoking history.

5p vimaine2711 26-03-2021 11 1   Download

As yet, little is known about the effects of mental health stigma on sustainable employment. This is surprising, as mental health stigma is common, and because people with severe and common mental disorders are 7 and 3 times more likely to be unemployed, respectively, than people with no disorders.

7p vigeorgia2711 30-11-2020 10 2   Download

Enzyme active sites can be connected to the exterior environment by one or more channels passing through the protein. Despite our current knowledge of enzyme structure and function, surprisingly little is known about how often channels are present or about any structural features such channels may have in common.

8p vikentucky2711 26-11-2020 7 1   Download

Induced aboveground plant defenses against pathogens can have negative effects on belowground microbial symbionts. While a considerable number of studies have utilized chemical elicitors to experimentally induce such defenses, there is surprisingly little evidence that actual aboveground pathogens affect root-associated microbes.

13p viminato2711 22-05-2020 11 0   Download

In 2002, the World Health Organization recommended that the age for starting complementary feeding should be changed from 4 to 6 months of age to 6 months. Although this change in age has generated substantial debate, surprisingly little attention has been paid to whether advice on how to introduce complementary foods should also be changed.

15p vichengna2711 25-02-2020 22 1   Download

Nevertheless, it is a widespread assumption that end-of-pipe technologies still domi- nate investment decisions in firms. This is because there has been exceptionally little empiri- cal analysis directed to the determinants of the use of specific types of abatement measures - principally because of the paucity of available data. On the basis of a unique facility-level data set based on a recent survey covering seven OECD countries (Canada, France, Germany, Hungary, Japan, Norway, and the U.S.) we find a clear dominance of cleaner production in these countries: Surprisingly, 76.

109p loixinloi 08-05-2013 65 6   Download

During thc past two decades, much work in linguistics has focused on sentences as minimal units of communication, and the project of rigorously characterizing the structure of sentences in natural language has met with some succcss. Not surprisingly, however, sentcnce grammars have contributed little to the analysis of discourse, Human discourse consists not just of words in sequences, hut of words in sequences directed by a speaker to an addressee, used to represent situations and to reveal intentions.

4p bungio_1 03-05-2013 45 4   Download

Miss Polly Harrington entered her kitchen a little hurriedly this June morning. Miss Polly did not usually make hurried movements; she specially prided herself on her repose of manner. But to-day she was hurrying—actually hurrying. Nancy, washing dishes at the sink, looked up in surprise. Nancy had been working in Miss Polly’s kitchen only two months, but already she knew that her mistress did not usually hurry. ‘Nancy!’ ‘Yes, ma’am.’ Nancy answered cheerfully, but she still continued wiping the pitcher in her hand.

243p subtraction1122 28-04-2013 34 4   Download

We arrived at Rye, a small English seaport. Here, as soon as we came on shore, we gave in our names to the notary of the place, but not till he had demanded our business; and being answered, that we had none but to see England, we were conducted to an inn, where we were very well entertained; as one generally is in this country. We took post-horses for London: it is surprising how swiftly they run; their bridles are very light, and their saddles little more than a span over. Flimwell, a village: here we returned our first horses, and mounted fresh ones. We passed through...

56p congacon88 26-04-2013 57 4   Download

Given the prevalence of the use of rhetorical relations in the generation of text (Itovy, 1989; Moore and Paris, 1988; Scott and Souza, 1990), it is surprising how little work has actually been done on the grammatical realization of these relations. Most systems, based on Mann and Thompson's formulation of Rhetorical Structure Theory (Mann and Thompson, 1988), have adopted simplified solutions to their expression. If, for example, an action, X, and a purpose for that action, Y, must be expressed, a standard form such as "Do X in order to Y" will be generated.

3p bunmoc_1 20-04-2013 39 2   Download

We investigate the effect of corpus size in combining supervised and unsupervised learning for two types of attachment decisions: relative clause attachment and prepositional phrase attachment. The supervised component is Collins’ parser, trained on the Wall Street Journal. The unsupervised component gathers lexical statistics from an unannotated corpus of newswire text. We find that the combined system only improves the performance of the parser for small training sets.

8p hongvang_1 16-04-2013 39 1   Download

While little need-based aid is offered to MBA’s, the high costs are sometimes offset by employers that are willing to pay a portion of the expenses. While we do not observe exactly how much the employer contributes toward the MBA, the survey does report whether an employer was the main source of financing (i.e., paid more the 50% of) the degree.

77p thieubaotrang 16-04-2013 48 4   Download

Very surprising it seems to assert that the Mother Country knows very little about the finest colony which she possesses--and that an enlightened people emigrate from sober, speculative England, sedate and calculating Scotland, and trusting, unreflective Ireland, absolutely and wholly ignorant of the total change of life to which they must necessarily submit in their adopted home.

97p nhokheo2 15-04-2013 48 3   Download

itle Little Sky-High; Or, the Surprising Doings of Washee-Washee-Wang (Dodo Press)Authors and contributors By (author) Hezekiah ButterworthPhysical properties Format: PaperbackNumber of pages: 76Width: 152 mmHeight: 229 mmThickness: 5 mmWeight: 122 gAudience General/tradeISBN ISBN 13: 9781409900146ISBN 10: 1409900142Classifications Nielsen BookScan Product Class: F1.1BICMainSubject: F......

75p nunongnuna 01-04-2013 55 4   Download

Taxation of financial intermediation receives surprisingly little ana- lytical attention, despite its practical importance both for national budgets and for the efficient functioning of the financial system. This volume is an attempt to provide a coherent overview of the policy issues involved.

461p layon_5 28-03-2013 70 9   Download

Consumer protection law and criminal law have both received considerable analysis from academic lawyers. The role of legal intervention with the aim of protecting the consumer has come in for scrutiny in a number of seminal works, many of which concentrate upon the role of consumer law in the marketplace. The role of criminal law has also been discussed by a large number of leading commentators, with particular attention being paid to the boundaries of criminal sanctions, and particular concern being addressed to increasing criminalisation.

269p haiduong_1 27-02-2013 71 15   Download