The by resolution of local

The structure of CLIC4, a member of the CLIC family of putative intracel-lular chloride ion channel proteins, has been determined at 1.8 A ˚ resolution by X-ray crystallography. The protein is monomeric and it is structurally similar to CLIC1, belonging to the GST fold class. Differences between the structures of CLIC1 and CLIC4 are localized to helix 2 in the glutaredoxin-like N-terminal domain, which has previously been shown to undergo a dra-matic structural change in CLIC1 upon oxidation.

12p fptmusic 12-04-2013 35 3   Download

A rat liver nuclear insoluble protein fraction was analyzed to investigate candidate proteins participating in nuclear architecture formation. Proteins were subjected to two-dimensional separation by reversed-phase HPLC in 60% formic acid and SDS⁄PAGE. The method produced good resolution of insoluble proteins. One hundred and thirty-eight proteins were separ-ated, and 28 of these were identified.

12p fptmusic 11-04-2013 62 2   Download

We give a proof of the Nirenberg-Treves conjecture: that local solvability of principal-type pseudo-differential operators is equivalent to condition (Ψ). This condition rules out sign changes from − to + of the imaginary part of the principal symbol along the oriented bicharacteristics of the real part. We obtain local solvability by proving a localizable a priori estimate for the adjoint operator with a loss of two derivatives (compared with the elliptic case).

41p noel_noel 17-01-2013 44 7   Download