Their genetic variety

An experiment was conducted to generate a broad genetic variability through induced mutation using physical and chemical mutagens. Three doses each of gamma rays (20, 40 and 60kR), ethyl methane sulphonate (0.2, 0.4 and 0.6%), nitrosoguanidine (0.005, 0.010, and 0.015%), maleic hydrazide (0.01, 0.02 and 0.03%) and their combinations were administered to the seed of two greengram varieties, Sujata and OBGG-52.

13p angicungduoc6 22-07-2020 21 3   Download

Strong increase in the production of genetically modified organisms (GMOs) observed over the years has led to a consolidation of transgenic seed industries worldwide. The dichotomy between the evaluated risk and the perceived risk of transgenic use has defined their level of acceptability among different global societies. GMOs have been widely applied to agricultural commodities, among them the Roundup Ready™ (RR™) soybean line GTS 40-3-2 has become the most prevalent transgenic crop in the world.

9p zingzing09 24-04-2013 47 4   Download

4-Hydroxy-2-trans-nonenal (4-HNE), one of the major end products of lipid peroxidation, has been shown to induce apoptosis in a variety of cell lines. It appears to modulate signalingprocesses inmore thanonewaybecause it has been suggested to have a role in signaling for differentiation and proliferation. We showfor the first time that incorporation of 4-HNE-metabolizing glutathioneS-transferase (GST) isozyme, hGSTA4-4, into adherent cell lines HLE B-3 and CCL-75, by either cDNA transfection or microinjection of active enzyme, leads to their transformation. ...

12p dell39 03-04-2013 46 3   Download

Cyclic nucleotide specific phosphodiesterases (PDEs) are important components of all cAMP signalling networks. In humans, 11 different PDE families have been identified to date, all of which belong to the class I PDEs. Pharmaco-logically, theyhavebecome of great interest as targets for the development of drugs for a large variety of clinical condi-tions. PDEs in parasitic protozoa have not yet been exten-sively investigated, despite their potential as antiparasitic drug targets.

11p dell39 03-04-2013 40 4   Download

The cuticles of most insect larvae have a variety of melanin patterns that function in the insects’ interactions with their biotic and abiotic environ-ments. Larvae of the armywormPseudaletia separatahave black and white stripes running longitudinally along the body axis. This pattern is empha-sized after the last larval molt by an increase in the contrast between the lines.

10p galaxyss3 21-03-2013 48 3   Download

Whereas significant knowledge is accumulating on the antibacterial and antifungal properties of host defense peptides (HDPs) and their synthetic mimics, much less is known of their activities against parasites. A variety ofin vitro andin vivo antiparasitic assays suggest that these notorious anti-microbial compounds could represent a powerful tool for the development of novel drugs to fight parasites in the vertebrate host or to complement current therapeutic strategies

9p viettel02 20-02-2013 40 3   Download

The ATP-binding cassette (ABC) transporters are a superfamily of mem-brane proteins that are best known for their ability to transport a wide variety of exogenous and endogenous substances across membranes against a concentration gradient via ATP hydrolysis.

20p cosis54 09-12-2012 62 3   Download

Abstract Resistance to conventional anticancer therapies in patients with advanced solid tumors has prompted the need of alternative cancer therapies. Moreover, the success of novel cancer therapies depends on their selectivity for cancer cells with limited toxicity to normal tissues. Several decades after Coley's work a variety of natural and genetically modified non-pathogenic bacterial species are being explored as potential antitumor agents, either to provide direct tumoricidal effects or to deliver tumoricidal molecules.

9p toshiba23 18-11-2011 59 2   Download

Eukaryotic genomes are full of long terminal repeat (LTR) retrotransposons. Although most LTR retrotransposons have common structural features and encode similar genes, there is nonetheless considerable diversity in their genomic organization, reflecting the different strategies they use to proliferate within the genomes of their hosts. reports deposited research Transposons are mobile genetic elements that can multiply in the genome using a variety of mechanisms. Retrotransposons replicate through...

0p thulanh21 15-11-2011 43 1   Download