Therapeutic methods
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Clear cell renal cell carcinoma (ccRCC) is the prevailing histological subtype of renal cell carcinoma and has unique metabolic reprogramming during its occurrence and development. Cell senescence is one of the newly identified tumor characteristics. However, there is a dearth of methodical and all-encompassing investigations regarding the correlation between the broad-ranging alterations in metabolic processes associated with aging and ccRCC.
23p vishanshan 27-06-2024 2 1 Download
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Ebook "Biomedical nanotechnology: Methods and protocols" is to provide an overview of biomedical nanotechnology, from the conception of novel materials in the laboratory to the application of such structures in the clinic. After a brief introductory chapter, the first section consists of protocol chapters which provide practical information on the synthesis of a variety of solution-phase and surface-bound nanomaterials and their application in sensing, imaging, and/or therapeutics; most chapters provide step-by-step instructions and insight into overcoming possible pitfalls and challenges.
447p dongmelo 27-05-2024 3 2 Download
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Ebook "Small molecule therapeutics for schizophrenia" covers all relevant aspects of drug research, e.g.
327p tracanhphuonghoa1007 22-04-2024 3 3 Download
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To evaluate the treatment results of combined blue light (415 nm wavelength) and red light (633 nm wavelength) therapy for patients with severe acne vulgaris. Subjects and methods: A pre-post comparative interventional study on 30 patients with severe acne vulgaris, examined and treated at the National Hospital of Dermatology and Venereology from July 2022 to June, 2023.
5p viohoyo 02-04-2024 4 1 Download
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Angiosarcoma is an aggressive tumor. Recent case series describe exceptional responses to checkpoint blockade in this disease. Methods: Herein, we explored the genomic correlates of 48 angiosarcomas from the Angiosarcoma Project (12,499 variants analyzed in 6603 genes; whole-exome sequencing) versus 10,106 pan-cancer tumors in The Cancer Genome Atlas including 235 sarcomas but no angiosarcoma.
6p vibransone 28-03-2024 4 2 Download
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Next-generation sequencing (NGS) of cancer gene panels are widely applied to enable personalized cancer therapy and to identify novel oncogenic mutations. Methods: We performed targeted NGS on 932 clinical cases of non-small-cell lung cancers (NSCLCs) using the Ion AmpliSeq™ Cancer Hotspot panel v2 assay.
11p vioraclene 31-03-2024 3 2 Download
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Identifying the complete repertoire of genes that drive cancer in individual patients is crucial for precision oncology. Most established methods identify driver genes that are recurrently altered across patient cohorts. However, mapping these genes back to patients leaves a sizeable fraction with few or no drivers, hindering our understanding of cancer mechanisms and limiting the choice of therapeutic interventions.
14p vibransone 28-03-2024 3 2 Download
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We present Beyondcell, a computational methodology for identifying tumour cell subpopulations with distinct drug responses in single-cell RNA-seq data and proposing cancer-specific treatments. Our method calculates an enrichment score in a collection of drug signatures, delineating therapeutic clusters (TCs) within cellular populations.
15p vibransone 28-03-2024 2 1 Download
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For patients with heart failure combined with complete left bundle branch block, cardiac resynchro‑ nization therapy is an important therapeutic method. If these patients also have atrial tachycardia, how to choose a treatment strategy deserves discussion.
6p vitiki 30-01-2024 3 2 Download
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Part 2 book "Cryptosporidium - Methods and protocols" includes content: Use of mirnas to study host cell–parasite interactions; genetic manipulation of cryptosporidium parvum with crispr cas9; mouse models for use in cryptosporidium infection studies and quantification of parasite burden using flow cytometry, QPCR, and histopathology; calf clinical model of cryptosporidiosis for efficacy evaluation of therapeutics,... and other contents.
201p muasambanhan05 16-01-2024 1 0 Download
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Ebook "Biomedical nanotechnology: Methods and protocols (Second edition)" provides an overview of some of the types of nanostructures commonly used in nanobiomedicine. The chapters in this book discuss practical information on the synthesis and characterization of a variety of solution-phase and surface-bound nanomaterials, with examples of how they can be used in sensing, imaging, and therapeutics.
342p lucchinguyen 28-12-2023 2 2 Download
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Ebook "Human T-lymphotropic viruses: Methods and protocols" detailed volume draws attention to other members of the Retrovirus family, namely the Human T-lymphotropic Viruses (HTLVs), featuring the most updated technical information about HTLV determination and the methods to investigate their interaction with the host immune system and interfering pathogens.
221p lucchinguyen 28-12-2023 6 2 Download
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Ebook "Argonaute proteins: Methods and protocols" aids researchers in examining these versatile proteins in a wide variety of cell types; features practical, step-by-step protocols which open the door to future progress in the field of molecular therapeutics; contains expert tips and vital implementation advice to ensure success;...
262p lucchinguyen 28-12-2023 6 2 Download
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Osteosarcoma is the most common primary bone cancer that affects mostly children and young adults. Despite the advances in osteosarcoma treatment, the long-term survival rate of metastatic patients has not significantly improved in the past few decades, thus demonstrating the need for novel therapeutic targets or methods to improve metastatic osteosarcoma treatment.
16p vialfrednobel 23-12-2023 4 4 Download
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Primary thyroid lymphoma (PTL) and papillary thyroid carcinoma (PTC) are both thyroid malignancies, but their therapeutic methods and prognosis are different. This study aims to explore their sonographic and computed tomography(CT)features, and to improve the early diagnosis rate.
9p vialfrednobel 23-12-2023 4 3 Download
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Part 1 book "Equine-Assisted therapy and learning with at risk young people" includes content: Background to equine assisted therapy and learning; young people considered "at risk", and overview of "the yard" and methods used; development of self confidence and self efficacy, and the opening up of "positive experiences" and "positive opportunities" through therapeutic horsemanship.
119p oursky10 04-12-2023 7 3 Download
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Part 2 book "Small animal clinical diagnosis by laboratory methods" includes content: Respiratory and cardiac disorders; immunologic and plasma protein disorders; reproductive disorders; neurologic disorders; microbiology and infectious disease; cytology of inflammatory or neoplastic masses; laboratory diagnostic toxicology; therapeutic drug monitoring.
159p oursky09 12-11-2023 9 3 Download
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To evaluate clinical and imaging characteristics, TNM staging of papillary thyroid carcinoma patients with cervical lymph node metastases at Can Tho Oncology Hospital between 2021 and 2023. Materials and methods: This was a descriptive cross-sectional study, including 52 patients who underwent total thyroidectomy and therapeutic neck dissection.
6p vispacex 16-11-2023 2 2 Download
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Burns, especially heat-related ones, are one of the most common injuries in work and daily life. To describe the clinical characteristics right at the time thermal burn patients were admitted to hospital and initial results of treating them by hyperbaric oxygen therapy.
7p vispacex 16-11-2023 6 2 Download
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Circulating tumor DNA (ctDNA) has been becoming a novel convenient and noninvasive method for dynamically monitoring landscape of genomic information to guild personalized cancer treatment. In this study we comprehensively evaluated the additional value of plasma ctDNA to routine tissue next generation sequencing (NGS) of therapeutically targetable mutations in lung cancers.
10p vischultz 20-10-2023 1 1 Download