Trained immunity

Ebook "Hot topics in infection and immunity in children V" e was scheduled for 23–25 June 2008 with another exciting programme and renowned speakers and we expect to produce a sixth edition of this book based on that course. Paediatric infectious diseases continue to grow and flourish in Europe with centres now being accredited for training by the European Society for Paediatric Infectious Diseases on behalf of the European Academy of Paediatrics.

267p tracanhphuonghoa1007 22-04-2024 4 2   Download

Major histocompatibility complex class II (MHC-II) molecules present peptide fragments to T cells for immune recognition. Current predictors for peptide to MHC-II binding are trained on binding affinity data, generated in vitro and therefore lacking information about antigen processing.

15p vibransone 28-03-2024 4 1   Download

Immune checkpoint inhibitors have revolutionized therapy of advanced and metastatic cancers. However, a significant proportion of patients do not respond to immune checkpoint inhibitors or develop resist‑ ance. Therefore, novel therapies or combinations of therapies that may act synergistically are needed.

7p vitiki 30-01-2024 5 2   Download

To accurately screen potential immune cells that can predict the survival of colorectal cancer (CRC) patients and identify related prognostic predictors. The sample data of CRC patients were downloaded from the GEO database as a training set to establish a prognosis-scoring model and screen prognosis-related immune cells. The sample data of CRC patients from the TCGA database were used as the validation set.

10p vischultz 20-10-2023 2 1   Download

The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored. We performed a randomized, controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees.

7p phuong10693 20-06-2023 7 1   Download

Tissues are complex milieus consisting of numerous cell types. Several recent methods have attempted to enumerate cell subsets from transcriptomes. However, the available methods have used limited sources for training and give only a partial portrayal of the full cellular landscape. Here we present xCell, a novel gene signature-based method, and use it to infer 64 immune and stromal cell types.

14p vialfrednobel 29-01-2022 11 0   Download

The bacillus Calmette-Guérin (BCG) vaccine protects against tuberculosis and heterologous infections but elicits high inter-individual variation in specific and nonspecific, or trained, immune responses. While the gut microbiome is increasingly recognized as an important modulator of vaccine responses and immunity in general, its potential role in BCG-induced protection is largely unknown.

22p viarchimedes 26-01-2022 12 0   Download

Since data representation is one of the factors that affect the training and testing time, a compact and complete detector generation algorithm is investigated; the thesis investigates optimal algorithms to generate detector set in AIS; they help to reduce both training time and detecting time of AIS-based IDSs.

103p larachdumlanat129 20-01-2021 15 3   Download

Cardiovascular disease (CVD) remains the largest cause of death in breast cancer survivors. The aim of this study was to explore the impact of exercise intensity on aerobic fitness and autonomic cardiac regulation (heart rate variability (HRV)) and salivary biomarkers of the stress systems (HPA-axis, cortisol; sympathetic nervous system, α-amylase) and mucosal immunity (secretory(s)-IgA), markers of increased risk of CVD in breast cancer survivors.

11p vimale2711 25-08-2020 36 3   Download

Aerobic exercise has been shown to slow tumor progression in rodents and humans, but the mechanisms behind this effect are still unclear. Here we show that aerobic exercise in the form of chronic endurance training suppresses tumor recruitment of FoxP3+ Treg cells thus enhancing antitumor immune efficiency.

10p vikuala271 13-06-2020 11 0   Download

Most rubberwood sawmills in present day Thailand are of the band saw type. Only the oldest ones still utilize circular saws despite the small diameter or the raw material. A typical sawmill consists of two production lines of one break- up saw and some four additional saws for resawing. The disadvantage of the bandsaw is the high level of maintenance required. The saw blades need sharpening every six hours by specially trained personnel using special equipment (Status of… 2000).

76p thieubaotrang 23-04-2013 58 3   Download

The Land Resources Development Centre, one of the scientific units of the Overseas Development Administration, assists developing countries in mapping, investigating and assessing land resources, and makes recommendations on the use of these resources for the development of agriculture, livestock husbandry and forestry; it also gives advice on related subjects to overseas governments and organisations, makes scientific personnel available for appointment abroad and provides lectures and training courses in the basic techniques of resource appraisal and development.

123p thieubaotrang 23-04-2013 46 5   Download

Education and training are particularly important in the current crisis. In times of recession, budget constraints (in government, households and businesses) tend to reduce expenditure on education and training. On the other hand, due to rising unemployment, demand for training increases. Support for education and training during the current crisis can help displaced workers find new job opportunities and can thus support the restructuring process.

139p trinhcaidat 19-04-2013 50 8   Download

Achieving your 10km goals is not just about completing the key sessions. There are other important aspects of performance. Remember to follow a sensible nutritional plan, from day to day, and pre and post training. Stretching is also an essential aspect of training. Stretching should be completed after each training session, as well as during designated stretching sessions 2-3 times per week. Improved flexibility will reduce the chance of injury, reduce fatigue, and improve running efficiency. Recovery is another crucial part of your training program that is often overlooked.

28p nhacsihuytuan 06-04-2013 48 5   Download

A sole-source contract is appropriate if your project is very small, if you already have experience in finding and working with conservation professionals, or if the project is so complex that bid specifications could be inconclusive. Be aware, however, that this option may not automatically be available when working with a government agency’s contracting office; you may have to seek an exception. Always make the case against a sealed bid process, in which cost is the sole determining factor.

8p yasuyidol 01-04-2013 50 4   Download

The primary purpose of this guideline is to improve diag- nostic accuracy for adult rhinosinusitis, reduce inappropri- ate antibiotic use, reduce inappropriate use of radiographic imaging, and promote appropriate use of ancillary tests that include nasal endoscopy, computed tomography, and testing for allergy and immune function. Secondary goals include creating a guideline suitable for deriving a performance measure on rhinosinusitis and training participants in guide- line methodology to facilitate future development efforts.

0p nhacnenzingme 28-03-2013 49 4   Download

Fostering Immunization Uptake in Argentina The pneumococcal vaccine was incorporated into the Argentinian national immunization scheme in April 2011, providing a way for infants to receive the vaccine for free beginning in 2012.

156p nhamnhiqa 01-03-2013 56 3   Download

It may be noted in this connection, on the one hand, that a population which is in no degree habituated to the modern industrial process is unable to adapt its mode of life to the requirements of this method of supplying human wants, and so can derive but little benefit, and possibly great discomfort, from a forcible intrusion of the machine industry; as, for instance, many of the outlying barbarian peoples with whom the Western industrial culture is now enforcing a close contact.

30p bi_ve_sau 05-02-2013 45 4   Download

School-related gender-based violence remains an obstacle to girls’ education. Efforts to address school safety are needed at all levels, including teacher training, community intervention and ministerial policy and practice. Ministries of Education can send a clear message that gender- based school violence will not be tolerated by firmly and quickly prosecuting perpetra- tors. Teacher training should include strong messages about professional and ethical conduct.

232p chiecxedien 02-01-2013 65 4   Download

Ian and Jane also became involved in processing and marketing their own products about five years ago. They found that there is a lot to learn about running a paddock- to-plate supply chain, including hiring staff and building strategic partnerships. Employment problems, particularly recruiting and training the right people, proved to be a significant issue for the business.

0p cao_can 02-01-2013 107 9   Download