Treatment integrity
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For patients with locally advanced rectal cancer (LARC), total neoadjuvant therapy (TNT), namely, intensifying preoperative treatment through the integration of radiotherapy and systemic chemotherapy before surgery, was commonly recommended as the standard treatment.
10p vishanshan 27-06-2024 1 1 Download
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Chemoradiotherapy is a critical treatment for patients with locally advanced and unresectable nonsmall cell lung cancer (NSCLC), and it is essential to identify high-risk patients as early as possible owing to the high incidence of radiation pneumonitis (RP). This study aimed to investigate the value of computed tomography (CT)-based radiomics combined with genomics in analyzing the risk of grade≥2 RP in unresectable stage III NSCLC.
10p vishanshan 27-06-2024 1 1 Download
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A significant proportion of patients and informal caregivers favor an active role in decisions concerning their health. Simultaneously, governments aim to shift treatment from a professional care setting to a community setting, in light of an ageing population, a decreasing number of health workers and allocation of scarce resources.
12p vishanshan 27-06-2024 1 1 Download
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The rapid evolution, complexity, and specialization of oncology treatment makes it challenging for physicians to provide care based on the latest and best evidence. We hypothesized that physicians would use evidencebased trusted care pathways if they were easy to use and integrated into clinical workfow at the point of care.
8p vishanshan 27-06-2024 2 1 Download
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This study aims to develop a nomogram integrating inflammation (NLR), Prognostic Nutritional Index (PNI), and EBV DNA (tumor burden) to achieve personalized treatment and prediction for stage IVA NPC. Furthermore, it endeavors to pinpoint specific subgroups that may derive significant benefits from S-1 adjuvant chemotherapy.
16p vishanshan 27-06-2024 1 1 Download
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Multicenter non-small cell lung cancer (NSCLC) patient data is information-rich. However, its direct integration becomes exceptionally challenging due to constraints involving different healthcare organizations and regulations.
11p vikoch 27-06-2024 2 1 Download
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Gastric cancer is one of the most common tumors worldwide, and most patients are deprived of treatment options when diagnosed at advanced stages. PRDM14 has carcinogenic potential in breast and non-small cell lung cancer. however, its role in gastric cancer has not been elucidated.
13p vikoch 27-06-2024 1 1 Download
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To evaluate the feasibility, safety and efficacy of concurrent simultaneous integrated boost intensitymodulated radiotherapy (SIB-IMRT) combined with nimotuzumab in the treatment of locally advanced esophageal squamous cell cancer (ESCC).
9p vikoch 27-06-2024 1 1 Download
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Glioblastoma (GBM) is an aggressive brain tumor that exhibits resistance to current treatment, making the identification of novel therapeutic targets essential. In this context, cellular prion protein (PrPC ) stands out as a potential candidate for new therapies.
17p vikoch 27-06-2024 3 1 Download
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Recently, propolis has shown potential cardioprotective effects against myocardial infarction. However, challenges in its clinical application have arisen, primarily due to concerns regarding dosage and potential adverse effects. To address this, we suggest integrating propolis into polyvinyl alcohol (PVA)/gelatin hydrogel to regulate the localized release of propolis at infarcted sites.
7p visergeyne 18-06-2024 0 0 Download
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This new edition of John Hannigan's well-known and respected text has been thoroughly revised to reflect recent conceptual and empirical advances in environmental sociology. The book offers a distinctive and even-handed treatment of environmental issues and debates, integrating European theoretical contributions such as risk society and ecological modernization with North American empirical insights and findings.
209p vimeyers 29-05-2024 2 2 Download
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Non-steroidal anti-inflammatory drug (NSAID) usage should be carefully considered based on gastrointestinal (GI) and cardiovascular (CV) risks. In light of restricted evidence, this study aims to assess the prescription of NSAIDs concerning the GI and CV risks in the integrated treatment of Traditional medicine (TM) and Western medicine (WM).
10p vicarlos 16-05-2024 2 0 Download
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The main aim of the current study is to investigate the relationship between the supply chain management practices and the Indonesian public healthcare organizational performance. Furthermore, the mediating role of alliance integrated network in the relationship between service supply chain management practices and the Indonesian public healthcare organizational performance is also examined. The study aims to overall assess the organizational performance of healthcare sector.
11p longtimenosee10 26-04-2024 2 1 Download
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Ebook "A clinical guide to the treatment of the human stress response (Third edition)" emphasizes the unique contribution of this longstanding text in the integration of mind/body relationships. The concept of stress, as defined and elaborated in Chapter 1, the primary efferent biological mechanisms of the human stress response, as described in Chapter 2, and the link from stress arousal to disease, as defined in Chapter 3, essentially remains the same. However, updates in microanatomy, biochemistry and tomography are added to these chapters.
489p tracanhphuonghoa1007 22-04-2024 4 2 Download
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Targeted therapies specifically act by blocking the activity of proteins that are encoded by genes critical for tumorigenesis. However, most cancers acquire resistance and long-term disease remission is rarely observed. Understanding the time course of molecular changes responsible for the development of acquired resistance could enable optimization of patients’ treatment options.
22p vibransone 28-03-2024 3 2 Download
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Although large-scale, next-generation sequencing (NGS) studies of cancers hold promise for enabling precision oncology, challenges remain in integrating NGS with clinically validated biomarkers. To overcome such challenges, we utilized the Database of Evidence for Precision Oncology (DEPO) to link druggability to genomic, transcriptomic, and proteomic biomarkers.
20p vibransone 28-03-2024 3 2 Download
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Ebook "Environmental and food safety and security for South-East Europe and Ukraine" covers important aspects of the field of food security and safety, ranging from fundamental production, through advanced water treatment technologies and detection of novel pollutants, to management and policy making. The discussion strives to develop an integrated approach to solving the associated problems by simultaneously considering sociological, ecological and economic aspects.
277p coduathanh1122 27-03-2024 5 1 Download
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Ebook "Male infertility: Contemporary clinical approaches, andrology, ART & antioxidants" offers a comprehensive review of well-established, current diagnostic and treatment techniques for male infertility. This state-of-the-art, evidence-based resource incorporates new multidisciplinary and complementary medicine approaches to create a first-of-its-kind guide to treatment strategies involving antioxidants for male infertility.
511p cotieubac1004 15-03-2024 7 0 Download
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Ebook "Biointensive integrated pest management in horticultural ecosystems" deals with the most recent biointensive integrated approaches for pest management utilizing components such as bioagents [predators, parasitoids and pathogens (bacteria, fungi, viruses)], botanicals (biofumigation, oil cakes, FYM, compost, crop residues, green manuring and other organic amendments), arbuscular mycorrhizal fungi, physical methods (hot water treatment of planting material, soil solarization), cultural methods (crop rotation, summer ploughing, fallowing, intercropping, pruning, mulching, spacing, plant...
278p manmanthanhla0201 26-02-2024 3 1 Download
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Ebook "Urea-SCR technology for deNOx after treatment of diesel exhausts" provides a complete overview of the selective catalytic reduction of NOx by ammonia/urea (urea-SCR), drawing from the know-how of many leading experts in the field.
715p nhanphanguyet 28-01-2024 4 2 Download