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Tuberculosis cases
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Tuberculosis continues to be a worldwide public health problem. Despite the noted gradual decline in tuberculosis case rates in the UK, clinicians should still be aware of these unusual presentations.
4p
vilazada
31-01-2024
4
2
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Primary myelofibrosis is a rare myeloproliferative disorder in middle-aged and old adults and should be distinguished from secondary and reactive causes of bone marrow fibrosis because, in reactive fibrosis, treatment approaches depend on the underlying etiology.
4p
vilazada
31-01-2024
9
2
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Pott disease is rare and responsible for only 1%–2% of all tuberculosis cases. It poses diagnostic challenges in resource-limited settings due to unusual presentation and limited investigative capacity, resulting in debilitating sequelae if diagnosed late.
5p
vitiki
30-01-2024
2
2
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Takayasu arteritis is a rare and chronic granulomatous vasculitis that affects the large vessels. Takayasu arteritis targets the aorta and its branches and is still of unknown etiology. It often affects female patients under 50 years of age. A relationship between Takayasu arteritis and tuberculosis has been suggested for a long time.
4p
vitiki
30-01-2024
5
2
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Chest X-ray offers high sensitivity and acceptable specificity as a tuberculosis screening tool, but in areas with a high burden of tuberculosis, there is often a lack of radiological expertise to interpret chest X-ray.
7p
vitiki
30-01-2024
7
2
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Several studies have compared the diagnostic value of sputum induction (SI) with flexible fiberoptic bronchoscopy (FOB) in diagnosing pulmonary tuberculosis; however, these investigations yield an inconsistent conclusion. This study aims to evaluate the role of acid-fast bacilli (AFB) testing of SI and bronchoalveolar lavage (BAL) samples in suspected pulmonary tuberculosis cases.
7p
vikissinger
21-12-2023
3
2
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The article would like to introduce a psoriatic arthritis (PsA) patient in the Department of Rheumatology of 108 Military Central Hospital. This case of PsA had the secondary tuberculosis infection after Tumor necrotic factor inhibitor (TNFi) treatment, nevertheless the articular destruction caused by PsA still went on.
6p
vishekhar
01-11-2023
2
0
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Tuberculosis (TB) is caused by Mycobacterium tuberculosis and most commonly occurs in the lung. Only 10-15% of all cases of tuberculosis occur outside the respiratory system. Whereas secondary tuberculosis of the tonsil, where there is sputum-positive pulmonary TB, has been well documented, primary tuberculosis of the tonsil without pulmonary TB is rare, and only a few cases have been reported up to now.
3p
viintuit
26-09-2023
1
0
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Although intestinal tuberculosis (ITB) typically affects ileocecal segments, the complication of tubercular enterocutaneous fistula is very rare. As an isolated phenomenon, primary intestinal manifestation without extraintestinal tuberculosis (TB) is exceptional and rarely reported.
4p
viintuit
26-09-2023
1
0
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Therapeutic blockade of tumour necrosis factor alpha (anti-TNF-α) is the mainstay treatment of several rheumatologic diseases. They are unfrequently associated with opportunistic infections and latent tuberculosis (TB) screening is paramount before immunosuppression. A 62-year-old man with psoriatic arthritis was under treatment with adalimumab for over 5 years.
4p
viintuit
26-09-2023
2
0
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This case highlights the significance of considering tuberculosis in the differential diagnosis of pericardial effusion and underscores the role of imaging and laboratory investigations in diagnosis. Management of tuberculous pericarditis involves a combination of antituberculous chemotherapy, pericardiocentesis, and corticosteroids.
6p
viintuit
26-09-2023
7
0
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Part 2 book "Antiparasitic and antibacterial drug discovery - From molecular targets to drug candidates" includes content: In search of trypanocidal drugs, trypanosomatid protein kinases as potential drug targets, chemotherapeutic development strategies for schistosomiasis, searching new antiparasitics in virtual space, chemical optimization of anthelmintic compounds – a case study,.... and other contents.
255p
oursky04
14-09-2023
5
4
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Develop a tool to disseminate integrated laboratory, clinical, and demographic case data necessary for improved contact tracing and outbreak detection of tuberculosis (TB).
7p
visteverogers
24-06-2023
3
2
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There is ample evidence indicating that immunosuppressive therapy or immune dysregulation in systemic lupus erythematosus increases the risk for tuberculosis. Interestingly, a few case reports suggest that tuberculosis could also be a risk factor for systemic lupus erythematosus and other autoimmune diseases.
6p
vigamora
23-05-2023
5
2
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Opportunistic infections are frequent in people living with the human immunodeficiency virus who either do not have access to antiretroviral therapy (ART) or use it irregularly. Tuberculosis is the most frequent infectious disease in PLHIV and can predispose patients to severe fungal infections with dire consequences.
4p
vigamora
23-05-2023
8
2
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Urinary tract tuberculosis (UTTB) is a common form of extrapulmonary tuberculosis (TB) which can infrequently present as renal carcinoma, leading to serious errors in the diagnosis and treatment of UTTB.
4p
vigamora
23-05-2023
6
2
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Primary psoas tuberculosis is the presence of “Koch’s bacillus’’ within the iliopsoas muscle caused by hematogenous or lymphatic seeding from a distant site. Muscular tuberculosis has relatively low prevalence in comparison with other cases of extrapulmonary tuberculosis, which explains the difficulties in establishing the diagnosis.
6p
vigamora
23-05-2023
8
3
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Human immunodeficiency virus/tuberculosis coinfections have amplified the multidrug-resistant tuberculosis pandemic in many countries in Sub-Saharan Africa, and multidrug-resistant tuberculosis has become a major public health threat.
8p
vigamora
23-05-2023
6
2
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Toll-like receptors play a key role in innate immunity by recognizing pathogens and activating appropriate responses. Pathogens express several signal molecules (pathogen-associated molecular patterns, PAMPs) essential for survival and pathogenicity. Recognition of PAMPs triggers an array of anti-microbial immune responses through the induction of various inflammatory cytokines.
8p
vinarcissa
21-03-2023
4
1
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The increase in new cases of drug resistance to first-line drugs such as ethambutol (ETB) makes it necessary to develop improvements for antituberculosis drugs. A new method for improving the bioavailability of active pharmaceutical ingredient (API) was investigated for preventing drug resistance and side-effects of antituberculosis drugs. In this study, an antituberculosis drug delivery system using β-cyclodextrin (β-CD) as the supramolecular carrier of ETB was prepared using the kneading method.
10p
lyhuyenthu
31-01-2023
3
1
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