Actin

The Wiskott–Aldrich syndrome protein (WASp) family of actin-nucleating factors are present in the cytoplasm and in the nucleus. The role of nuclear WASp for T cell development remains incompletely defined. Methods: We performed WASp chromatin immunoprecipitation and deep sequencing (ChIP-seq) in thymocytes and spleen CD4+ T cells.

18p vioraclene 31-03-2024 1 1   Download

Ebook "Actin-monomer-bindingproteins (Molecular biology intelligence unit series)" summarizes the current knowledge on actin dynamics and presents examples of how actin monomer binding proteins regulate actin filament assembly and contribute to various cellular processes. It is important to note that many actin monomer binding proteins also display other activities besides interaction with unpolymerized actin.

127p duongthandue0501 28-02-2024 4 1   Download

Ebook "Sexual reproduction in animals and plants" contains the proceedings of the International Symposium on the Mechanisms of Sexual Reproduction in Animals and Plants, where many plant and animal reproductive biologists gathered to discuss their recent progress in investigating the shared mechanisms and factors involved in sexual reproduction. This now is the first book that reviews recent progress in almost all fields of plant and animal fertilization.

463p manmanthanhla0201 26-02-2024 1 1   Download

Ebook "Neurobiology of actin: From neurulation to synaptic function" is an introduction to the interface between the actin cytoskeleton and the myriad of issues fundamental to the understanding of the nervous system. It covers the neurobiology of actin ranging from basic cellular organization and function to the roles of actin in the health and disease states of the nervous system.

288p tachieuhoa 28-01-2024 5 2   Download

Gliomas are the most common malignant brain tumors, with powerful invasiveness and an undesirable prognosis. Actin-related protein 2/3 complex subunit 5 (ARPC5) encodes a component of the Arp2/3 protein complex, which plays a significant role in regulating the actin cytoskeleton.

14p visharma 20-10-2023 2 2   Download

Breast cancer brain metastasis (BCBM) is a growing therapeutic challenge and clinical concern. Stromal cancer-associated fibroblasts (CAFs) are crucial factors in the modulation of tumorigeneses and metastases.

12p visharma 20-10-2023 3 2   Download

The extracellular matrix (ECM) has a complicated nano- and macro-architecture. We prepared poly-Llactic acid (PLLA)-ECM substrates derived from mesenchymal stem cells (MSCs) by culturing cells on PLLA electro-spun fiber membranes of three different diameters.

10p viberbers 09-08-2023 4 2   Download

Bài viết Bước đầu nghiên cứu sự hiện diện của Sri Lankan Cassava Mosaic Virus (SLCMV) trên sắn (Manihot esculenta Crantz 1766) phân tích các yếu tố có thể gia tăng hiệu suất tách chiết ssDNA và hướng đến chuẩn hoá một số yếu tố trong quy trình thu mẫu, tách chiết cho phép phát hiện sự hiện diện SLCMV trong vật liệu.

16p vinebula 02-06-2023 4 2   Download

Caudata species such as salamanders are easily affected by environmental changes, which can drastically reduce their population. The effects of acute X-rays and chronic γ-irradiation on Hynobius lichenatus, the Japanese Tohoku hynobiid salamander, are known.

14p vihagrid 30-01-2023 6 3   Download

Invadopodia, actin-rich structures that release metallo-proteases at the interface with extra-cellular matrix, in a punctate manner are thought to be important drivers of tumour invasion. Invadopodia formation has been observed in-vitro and in-vivo in numerous metastatic cell lines derived from multiple tumour types.

9p vikolindagrabar 27-07-2022 6 2   Download

Đề tài ngiên cứu nhằm mô tả các hình thái lâm sàng và giải phẫu bệnh của ung thư ống tiêu hóa không thuộc biểu mô; mô tả các phương pháp phẫu thuật và đánh giá kết quả điều trị phẫu thuật của ung thư ống tiêu hóa không thuộc biểu mô. Mời các bạn cùng tham khảo nội dung chi tiết.

197p badbuddy10 21-04-2022 12 4   Download

Mục tiêu của đề tài là mô tả các hình thái lâm sàng và giải phẫu bệnh của ung thư ống tiêu hóa không thuộc biểu mô; mô tả các phương pháp phẫu thuật và đánh giá kết quả điều trị phẫu thuật của ung thư ống tiêu hóa không thuộc biểu mô. Mời các bạn cùng tham khảo nội dung chi tiết.

27p badbuddy10 21-04-2022 15 1   Download

The calcium sensitizer levosimendan is increasingly used to improve hemodynamics in patients with acutely decompensated heart failure. By binding to cardiac troponin C the conformation of the calcium-troponin C complex is stabilized, which leads to acceleration of actin-myosin crossbrigde formation and increased force generating capacity of muscle fibers.

5p vampires36 30-12-2021 14 0   Download

The differential diagnosis of endometrial stromal tumor (EST) and uterine cellular leiomyoma (CL) remains a challenge in clinical practice, especially low grade endometrial stromal sarcoma (ESS) and CL, suggesting the need for novel immunomarkers panels for differential diagnosis.

9p vimahuateng 26-11-2021 7 0   Download

Cutaneous squamous cell carcinoma (cSCC) often follows actinic keratosis (AK) and is the second most common skin cancer worldwide. To reduce metastasis risk, it is important to diagnose and treat cSCC early. This study aimed to identify hub genes associated with cSCC and AK.

12p vimahuateng 26-11-2021 11 1   Download

Caenorhabditis elegans can endure long periods of environmental stress by altering their development to execute a quiescent state called “dauer”. Previous work has implicated LKB1 - the causative gene in the autosomal dominant, cancer pre-disposing disease called Peutz-Jeghers Syndrome (PJS), and its downstream target AMPK, in the establishment of germline stem cell (GSC) quiescence during the dauer stage.

19p vibeauty 23-10-2021 11 1   Download

High hydrostatic pressure and low temperatures make the deep sea a harsh environment for life forms. Actin organization and microtubules assembly, which are essential for intracellular transport and cell motility, can be disrupted by high hydrostatic pressure. High hydrostatic pressure can also damage DNA. Nucleic acids exposed to low temperatures can form secondary structures that hinder genetic information processing.

9p vibeauty 23-10-2021 13 1   Download

To unveil the mechanisms underlying the rubber yield, transcript levels of nine major latex metabolism-related genes, i.e., HMG-CoA synthase (HMGS), HMG-CoA reductase (HMGR), diphosphomevalonate decarboxylase (PMD), farnesyl diphosphate synthase (FPS), cis-prenyltransferase (CPT), rubber elongation factor (REF), small rubber particle protein (SRPP), dihydroxyacid dehydratase (DHAD) and actin depolymerizing factor (ADF), were dertermined, and the relationship between rubber yield with their expression levels was analysed.

18p viseulgi2711 31-08-2021 8 1   Download

Considering the main function of GMFG in actin remodeling, which is vital for immune response, angiogenesis, cell division and motility, GMFG is supposed to have important roles in tumor development, while up to now, only two studies described the role of GMFG in cancers.

10p vianrose2711 27-04-2021 11 1   Download

The breakdown of alveolar barrier dysfunction contributes to Lipopolysaccharide stimulated pulmonary edema and acute lung injury. Actin cytoskeleton has been implicated to be critical in regulation of epithelial barrier.

10p vimontana2711 05-04-2021 6 0   Download